Trefoil Factor 3 Monoclonal Antibody (5UCLNT3), eBioscience | Invitrogen 14-4758-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Trefoil Factor 3 Monoclonal Antibody (5UCLNT3), eBioscience

catalog :

14-4758-82

quantity :

100 ug

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5UCLNT3

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 4

Reference
Belle N, Ji Y, Herbine K, Wei Y, Park J, Zullo K, et al. TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths. Nat Commun. 2019;10:4408 pubmed publisher
Ahmed A, Griffiths A, Tilby M, Westley B, May F. TFF3 is a normal breast epithelial protein and is associated with differentiated phenotype in early breast cancer but predisposes to invasion and metastasis in advanced disease. Am J Pathol. 2012;180:904-16 pubmed publisher
Yu Y, Jin H, Holder D, Ozer J, Villarreal S, Shughrue P, et al. Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury. Nat Biotechnol. 2010;28:470-7 pubmed publisher
Wong W, Poulsom R, Wright N. Trefoil peptides. Gut. 1999;44:890-5 pubmed

product information

Product Type :

Antibody

Product Name :

Trefoil Factor 3 Monoclonal Antibody (5UCLNT3), eBioscience

Catalog # :

14-4758-82

Quantity :

100 ug

Price :

US 399.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 0.5 ug/mL, Western Blot: Assay-Dependent

Species :

Mouse, Rat

Clone :

5UCLNT3

Isotype :

IgG1, kappa

Storage :

4 C

Description :

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 0.5 ug/mL, Western Blot: Assay-Dependent

Aliases :

hITF; hP1.B; Intestinal trefoil factor; ITF; mITF; P1B; Polypeptide P1.B; rITF; rP1.B; Tff3; TFI; Trefoil factor 3; trefoil factor 3 (intestinal); trefoil factor 3, intestinal