Rat IgG1 kappa Isotype Control (eBRG1), eBioscience | Invitrogen 14-4301-82 product information

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product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

other

product name :

Rat IgG1 kappa Isotype Control (eBRG1), eBioscience

catalog :

14-4301-82

quantity :

100 ug

price :

US 109.00

citations: 25

Reference
Cheng Y, Zhu X, Wang X, Zhuang Q, Huyan X, Sun X, et al. Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Front Immunol. 2018;9:1566 pubmed publisher
Napolitano A, van der Veen A, Bunyan M, Borg A, Frith D, Howell S, et al. Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection. J Immunol. 2018;201:604-614 pubmed publisher
Heuston E, Keller C, Lichtenberg J, Giardine B, Anderson S, Hardison R, et al. Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points. Epigenetics Chromatin. 2018;11:22 pubmed publisher
Friedrich C, Mamareli P, Thiemann S, Kruse F, Wang Z, Holzmann B, et al. MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. PLoS Pathog. 2017;13:e1006357 pubmed publisher
Sindhava V, Oropallo M, Moody K, Naradikian M, Higdon L, Zhou L, et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017;127:1651-1663 pubmed publisher
Nullens S, Staessens M, Peleman C, Plaeke P, Malhotra Kumar S, Francque S, et al. Beneficial Effects of Anti-Interleukin-6 Antibodies on Impaired Gastrointestinal Motility, Inflammation and Increased Colonic Permeability in a Murine Model of Sepsis Are Most Pronounced When Administered in a Preventive Setup. PLoS ONE. 2016;11:e0152914 pubmed publisher
Le Noci V, Tortoreto M, Gulino A, Storti C, Bianchi F, Zaffaroni N, et al. Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment. Oncoimmunology. 2015;4:e1040214 pubmed
Yao Y, Vent Schmidt J, McGeough M, Wong M, Hoffman H, Steiner T, et al. Tr1 Cells, but Not Foxp3+ Regulatory T Cells, Suppress NLRP3 Inflammasome Activation via an IL-10-Dependent Mechanism. J Immunol. 2015;195:488-97 pubmed publisher
Fontana M, Baccarella A, Pancholi N, Pufall M, Herbert D, Kim C. JUNB is a key transcriptional modulator of macrophage activation. J Immunol. 2015;194:177-86 pubmed publisher
Donaldson D, Bradford B, Artis D, Mabbott N. Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23. Mucosal Immunol. 2015;8:582-95 pubmed publisher
Hui J, Tsourkas A. Optimization of photoactive protein Z for fast and efficient site-specific conjugation of native IgG. Bioconjug Chem. 2014;25:1709-19 pubmed publisher
Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, et al. Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-?. J Exp Med. 2014;211:1393-405 pubmed publisher
Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, et al. Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Infect Immun. 2014;82:3723-39 pubmed publisher
Arnold J, Magiera L, Kraman M, Fearon D. Tumoral immune suppression by macrophages expressing fibroblast activation protein-Î± and heme oxygenase-1. Cancer Immunol Res. 2014;2:121-6 pubmed publisher
Liu Y, Liu A, Iikuni N, Xu H, Shi F, La Cava A. Regulatory CD4+ T cells promote B cell anergy in murine lupus. J Immunol. 2014;192:4069-73 pubmed publisher
Richert L, Rynda Apple A, Harmsen A, Han S, Wiley J, Douglas T, et al. CD11c? cells primed with unrelated antigens facilitate an accelerated immune response to influenza virus in mice. Eur J Immunol. 2014;44:397-408 pubmed publisher
Paveglio S, Puddington L, Rafti E, Matson A. FcRn-mediated intestinal absorption of IgG anti-IgE/IgE immune complexes in mice. Clin Exp Allergy. 2012;42:1791-800 pubmed publisher
Kukita A, Ichigi Y, Takigawa I, Watanabe T, Kukita T, Miyamoto H. Infection of RANKL-primed RAW-D macrophages with Porphyromonas gingivalis promotes osteoclastogenesis in a TNF-?-independent manner. PLoS ONE. 2012;7:e38500 pubmed publisher
Rynda Apple A, Dobrinen E, McAlpine M, Read A, Harmsen A, Richert L, et al. Virus-like particle-induced protection against MRSA pneumonia is dependent on IL-13 and enhancement of phagocyte function. Am J Pathol. 2012;181:196-210 pubmed publisher
Klezovich Bénard M, Corre J, Jusforgues Saklani H, Fiole D, Burjek N, Tournier J, et al. Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins. PLoS Pathog. 2012;8:e1002481 pubmed publisher
Ye F, Han L, Lu Q, Dong W, Chen Z, Shao H, et al. Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice. J Immunol. 2011;187:4178-86 pubmed publisher
Wei J, Loke P, Zang X, Allison J. Tissue-specific expression of B7x protects from CD4 T cell-mediated autoimmunity. J Exp Med. 2011;208:1683-94 pubmed publisher
Hovhannisyan Z, Treatman J, Littman D, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology. 2011;140:957-65 pubmed publisher
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product information

Product Type :

Isotype Control

Product Name :

Rat IgG1 kappa Isotype Control (eBRG1), eBioscience

Catalog # :

14-4301-82

Quantity :

100 ug

Price :

US 109.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Applications :

Control: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent

Clone :

eBRG1

Isotype :

IgG1, kappa

Storage :

4 C

Description :

Rat IgG1 is a subclass of immunoglobulin G (IgG) antibodies that are commonly used in research and diagnostics. These antibodies are produced by rats in response to an antigen and can be purified from serum or hybridoma cell culture supernatants. Rat IgG1 is often used as a negative control in experiments, as it does not bind to many mammalian antigens. It is also used in immunohistochemistry, flow cytometry, and western blotting to detect specific antigens. Gene targeting is a powerful tool used to manipulate the rat genome and generate animal models for studying human diseases. With gene targeting, specific genes can be knocked out, inserted, or modified to investigate their role in disease pathogenesis.

Format :

Liquid

Applications w/Dilutions :

Control: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

Immunoglobulin G; Immunoglobulin G1; ImmunoglobulinG; ImmunoglobulinG1