Rat IgG1 kappa Isotype Control (eBRG1), eBioscience™ | Invitrogen 14-4301-81 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

other

product name :

Rat IgG1 kappa Isotype Control (eBRG1), eBioscience™

catalog :

14-4301-81

quantity :

50 µg

price :

US 309.00

citations: 25

Reference
Cheng Y, Zhu X, Wang X, Zhuang Q, Huyan X, Sun X, et al. Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Front Immunol. 2018;9:1566 pubmed publisher
Napolitano A, van der Veen A, Bunyan M, Borg A, Frith D, Howell S, et al. Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection. J Immunol. 2018;201:604-614 pubmed publisher
Heuston E, Keller C, Lichtenberg J, Giardine B, Anderson S, Hardison R, et al. Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points. Epigenetics Chromatin. 2018;11:22 pubmed publisher
Friedrich C, Mamareli P, Thiemann S, Kruse F, Wang Z, Holzmann B, et al. MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. PLoS Pathog. 2017;13:e1006357 pubmed publisher
Sindhava V, Oropallo M, Moody K, Naradikian M, Higdon L, Zhou L, et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017;127:1651-1663 pubmed publisher
Nullens S, Staessens M, Peleman C, Plaeke P, Malhotra Kumar S, Francque S, et al. Beneficial Effects of Anti-Interleukin-6 Antibodies on Impaired Gastrointestinal Motility, Inflammation and Increased Colonic Permeability in a Murine Model of Sepsis Are Most Pronounced When Administered in a Preventive Setup. PLoS ONE. 2016;11:e0152914 pubmed publisher
Le Noci V, Tortoreto M, Gulino A, Storti C, Bianchi F, Zaffaroni N, et al. Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment. Oncoimmunology. 2015;4:e1040214 pubmed
Yao Y, Vent Schmidt J, McGeough M, Wong M, Hoffman H, Steiner T, et al. Tr1 Cells, but Not Foxp3+ Regulatory T Cells, Suppress NLRP3 Inflammasome Activation via an IL-10-Dependent Mechanism. J Immunol. 2015;195:488-97 pubmed publisher
Fontana M, Baccarella A, Pancholi N, Pufall M, Herbert D, Kim C. JUNB is a key transcriptional modulator of macrophage activation. J Immunol. 2015;194:177-86 pubmed publisher
Donaldson D, Bradford B, Artis D, Mabbott N. Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23. Mucosal Immunol. 2015;8:582-95 pubmed publisher
Hui J, Tsourkas A. Optimization of photoactive protein Z for fast and efficient site-specific conjugation of native IgG. Bioconjug Chem. 2014;25:1709-19 pubmed publisher
Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, et al. Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-?. J Exp Med. 2014;211:1393-405 pubmed publisher
Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, et al. Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Infect Immun. 2014;82:3723-39 pubmed publisher
Arnold J, Magiera L, Kraman M, Fearon D. Tumoral immune suppression by macrophages expressing fibroblast activation protein-Î± and heme oxygenase-1. Cancer Immunol Res. 2014;2:121-6 pubmed publisher
Liu Y, Liu A, Iikuni N, Xu H, Shi F, La Cava A. Regulatory CD4+ T cells promote B cell anergy in murine lupus. J Immunol. 2014;192:4069-73 pubmed publisher
Richert L, Rynda Apple A, Harmsen A, Han S, Wiley J, Douglas T, et al. CD11c? cells primed with unrelated antigens facilitate an accelerated immune response to influenza virus in mice. Eur J Immunol. 2014;44:397-408 pubmed publisher
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Kukita A, Ichigi Y, Takigawa I, Watanabe T, Kukita T, Miyamoto H. Infection of RANKL-primed RAW-D macrophages with Porphyromonas gingivalis promotes osteoclastogenesis in a TNF-?-independent manner. PLoS ONE. 2012;7:e38500 pubmed publisher
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Klezovich Bénard M, Corre J, Jusforgues Saklani H, Fiole D, Burjek N, Tournier J, et al. Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins. PLoS Pathog. 2012;8:e1002481 pubmed publisher
Ye F, Han L, Lu Q, Dong W, Chen Z, Shao H, et al. Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice. J Immunol. 2011;187:4178-86 pubmed publisher
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product information

Product Type :

Isotype Control

Product Name :

Rat IgG1 kappa Isotype Control (eBRG1), eBioscience™

Catalog # :

14-4301-81

Quantity :

50 µg

Price :

US 309.00

Clonality :

Control

Purity :

Affinity chromatography

Host :

Rat

Applications :

Control: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry: Assay-Dependent

Clone :

eBRG1

Isotype :

IgG1, kappa

Storage :

4° C

Description :

The isotype of a primary antibody and the application it is being used in can result in background staining. Primary antibody background noise can be caused by binding to Fc receptors on target cells; by non-specific interactions with cellular proteins, carbohydrates, and lipids; or by cell autofluorescence. Isotype control antibodies can act as negative controls to help differentiate non-specific background signal from specific antibody signal because they have no relevant specificity to a target antigen. While isotype controls are most commonly used in flow cytometry, they are useful in other applications such as chromatin immunoprecipitation (ChIP), immunohistochemistry, and gel shifts. Isotype controls should match with the primary antibody species and isotype so that the level of specific staining by the primary antibody may be accurately determined. If using directly labeled primary antibodies, the isotype control works best if conjugated with the same label as the test antibody.

Format :

Liquid

Applications w/Dilutions :

Control: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry: Assay-Dependent

Aliases :

Immunoglobulin G; Immunoglobulin G1; ImmunoglobulinG; ImmunoglobulinG1