CD321 (F11R) Monoclonal Antibody (CSTEM27), eBioscience | Invitrogen 14-3219-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD321 (F11R) Monoclonal Antibody (CSTEM27), eBioscience

catalog :

14-3219-37

quantity :

2 mg

price :

US 1474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CSTEM27

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry

citations: 3

Reference
Osman I, Garrec C, de Souza G, Zarubica A, Belhaouari D, Baudoin J, et al. Control of CDH1/E-Cadherin Gene Expression and Release of a Soluble Form of E-Cadherin in SARS-CoV-2 Infected Caco-2 Intestinal Cells: Physiopathological Consequences for the Intestinal Forms of COVID-19. Front Cell Infect Microbiol. 2022;12:798767 pubmed publisher
Raghavan S, Kenchappa D, Leo M. SARS-CoV-2 Spike Protein Induces Degradation of Junctional Proteins That Maintain Endothelial Barrier Integrity. Front Cardiovasc Med. 2021;8:687783 pubmed publisher
Matsubara J, Tian Y, Cui J, Zeglinski M, Hiroyasu S, Turner C, et al. Retinal Distribution and Extracellular Activity of Granzyme B: A Serine Protease That Degrades Retinal Pigment Epithelial Tight Junctions and Extracellular Matrix Proteins. Front Immunol. 2020;11:574 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD321 (F11R) Monoclonal Antibody (CSTEM27), eBioscience

Catalog # :

14-3219-37

Quantity :

2 mg

Price :

US 1474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 ug/test, Immunocytochemistry: 5 ug/mL, Western Blot: 5 ug/mL

Species :

Human

Clone :

CSTEM27

Isotype :

IgG2a, kappa

Storage :

4 C, do not freeze

Description :

CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test, Immunocytochemistry: 5 ug/mL, Western Blot: 5 ug/mL

Aliases :

9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301