CD277 Monoclonal Antibody (eBioBT3.1 (20.1, BT3.1)), eBioscience | Invitrogen 14-2779-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD277 Monoclonal Antibody (eBioBT3.1 (20.1, BT3.1)), eBioscience

catalog :

14-2779-95

quantity :

10 mg

price :

US 3740.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eBioBT3.1 (20.1, BT3.1)

reactivity :

human

application :

immunoprecipitation, flow cytometry

citations: 5

Reference
Karunakaran M, Willcox C, Salim M, Paletta D, Fichtner A, Noll A, et al. Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing. Immunity. 2020;52:487-498.e6 pubmed publisher
de Bruin R, Stam A, Vangone A, van Bergen en Henegouwen P, Verheul H, Sebestyen Z, et al. Prevention of V?9V?2 T Cell Activation by a V?9V?2 TCR Nanobody. J Immunol. 2017;198:308-317 pubmed
Le Page C, Marineau A, Bonza P, Rahimi K, Cyr L, Labouba I, et al. BTN3A2 expression in epithelial ovarian cancer is associated with higher tumor infiltrating T cells and a better prognosis. PLoS ONE. 2012;7:e38541 pubmed publisher
Cubillos Ruiz J, Martinez D, Scarlett U, Rutkowski M, Nesbeth Y, Camposeco Jacobs A, et al. CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells. Oncotarget. 2010;1:329-38 pubmed
Yamashiro H, Yoshizaki S, Tadaki T, Egawa K, Seo N. Stimulation of human butyrophilin 3 molecules results in negative regulation of cellular immunity. J Leukoc Biol. 2010;88:757-67 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD277 Monoclonal Antibody (eBioBT3.1 (20.1, BT3.1)), eBioscience

Catalog # :

14-2779-95

Quantity :

10 mg

Price :

US 3740.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 ug/test, Immunoprecipitation: Assay-Dependent

Species :

Human

Clone :

eBioBT3.1 (20.1, BT3.1)

Isotype :

IgG1

Storage :

4 C

Description :

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene and the BTN2 and BTN3 genes, which have undergone tandem duplication, resulting in 3 copies of each.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test, Immunoprecipitation: Assay-Dependent

Aliases :

BT3.1; BTF5; BTN3.1; BTN3A1; butyrophilin; Butyrophilin subfamily 3 member A1; butyrophilin, subfamily 3, member A1; CD277; dJ45P21.3 (butyrophilin, subfamily 3, member A1)