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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD277 Monoclonal Antibody (eBioBT3.1 (20.1, BT3.1)), eBioscience
catalog :
14-2779-82
quantity :
100 µg
price :
US 274.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
eBioBT3.1 (20.1, BT3.1)
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig st1
Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  • flow cytometry; human
  • immunohistochemistry; human; loading ...; fig 5
Cubillos Ruiz J, Martinez D, Scarlett U, Rutkowski M, Nesbeth Y, Camposeco Jacobs A, et al. CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells. Oncotarget. 2010;1:329-38 pubmed
Karunakaran M, Willcox C, Salim M, Paletta D, Fichtner A, Noll A, et al. Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing. Immunity. 2020;52:487-498.e6 pubmed publisher
Le Page C, Marineau A, Bonza P, Rahimi K, Cyr L, Labouba I, et al. BTN3A2 expression in epithelial ovarian cancer is associated with higher tumor infiltrating T cells and a better prognosis. PLoS ONE. 2012;7:e38541 pubmed publisher
Yamashiro H, Yoshizaki S, Tadaki T, Egawa K, Seo N. Stimulation of human butyrophilin 3 molecules results in negative regulation of cellular immunity. J Leukoc Biol. 2010;88:757-67 pubmed publisher
Compte E, Pontarotti P, Collette Y, Lopez M, Olive D. Frontline: Characterization of BT3 molecules belonging to the B7 family expressed on immune cells. Eur J Immunol. 2004;34:2089-99 pubmed
Tazi Ahnini R, Henry J, Offer C, Bouissou Bouchouata C, Mather I, Pontarotti P. Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex. Immunogenetics. 1997;47:55-63 pubmed
product information
Product Type :
Antibody
Product Name :
CD277 Monoclonal Antibody (eBioBT3.1 (20.1, BT3.1)), eBioscience
Catalog # :
14-2779-82
Quantity :
100 µg
Price :
US 274.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1 µg/test, Immunoprecipitation: Assay-Dependent
Species :
Human
Clone :
eBioBT3.1 (20.1, BT3.1)
Isotype :
IgG1
Storage :
4° C
Description :
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene and the BTN2 and BTN3 genes, which have undergone tandem duplication, resulting in 3 copies of each.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/test, Immunoprecipitation: Assay-Dependent
Aliases :
BT3.1; BTF5; BTN3.1; BTN3A1; butyrophilin; Butyrophilin subfamily 3 member A1; butyrophilin, subfamily 3, member A1; CD277; dJ45P21.3 (butyrophilin, subfamily 3, member A1)
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA