CD207 (Langerin) Monoclonal Antibody (eBioL31), eBioscience | Invitrogen 14-2075-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD207 (Langerin) Monoclonal Antibody (eBioL31), eBioscience

catalog :

14-2075-37

quantity :

2 mg

price :

US 1474.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBioL31

reactivity :

mouse

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

citations: 16

Reference
Nasir G, Sinnis P. Transport of antibody into the skin is only partially dependent upon the neonatal Fc-receptor. PLoS ONE. 2023;18:e0273960 pubmed publisher
Chung J, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest. 2017;127:1574-1588 pubmed publisher
Guerrini M, Okamoto K, Komatsu N, Sawa S, Danks L, Penninger J, et al. Inhibition of the TNF Family Cytokine RANKL Prevents Autoimmune Inflammation in the Central Nervous System. Immunity. 2015;43:1174-85 pubmed publisher
Trautwein Weidner K, Gladiator A, Kirchner F, Becattini S, Rülicke T, Sallusto F, et al. Antigen-Specific Th17 Cells Are Primed by Distinct and Complementary Dendritic Cell Subsets in Oropharyngeal Candidiasis. PLoS Pathog. 2015;11:e1005164 pubmed publisher
Capucha T, Mizraji G, Segev H, Blecher Gonen R, Winter D, Khalaileh A, et al. Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes. Immunity. 2015;43:369-81 pubmed publisher
Hobbs R, DePianto D, Jacob J, Han M, Chung B, Batazzi A, et al. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nat Genet. 2015;47:933-8 pubmed publisher
Stary G, Olive A, Radovic Moreno A, Gondek D, Alvarez D, Basto P, et al. VACCINES. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells. Science. 2015;348:aaa8205 pubmed publisher
Hansell C, Maclellan L, Oldham R, Doonan J, Chapple K, Anderson E, et al. The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens. Immunol Cell Biol. 2015;93:167-76 pubmed publisher
Berres M, Lim K, Peters T, Price J, Takizawa H, Salmon H, et al. BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. J Exp Med. 2014;211:669-83 pubmed publisher
Heine S, Diaz McNair J, Andar A, Drachenberg C, Van de Verg L, Walker R, et al. Intradermal delivery of Shigella IpaB and IpaD type III secretion proteins: kinetics of cell recruitment and antigen uptake, mucosal and systemic immunity, and protection across serotypes. J Immunol. 2014;192:1630-40 pubmed publisher
Elnekave M, Furmanov K, Shaul Y, Capucha T, Eli Berchoer L, Zelentsova K, et al. Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming. J Immunol. 2014;192:1395-403 pubmed publisher
Freire T, Zhang X, Deriaud E, Ganneau C, Vichier Guerre S, Azria E, et al. Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant. Blood. 2010;116:3526-36 pubmed publisher
Kratzer R, Mauvais F, Burgevin A, Barilleau E, van Endert P. Fusion proteins for versatile antigen targeting to cell surface receptors reveal differential capacity to prime immune responses. J Immunol. 2010;184:6855-64 pubmed publisher
MANICONE A, Huizar I, McGuire J. Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin). Am J Pathol. 2009;175:2319-31 pubmed publisher
Qiu C, Miyake Y, Kaise H, Kitamura H, Ohara O, Tanaka M. Novel subset of CD8{alpha}+ dendritic cells localized in the marginal zone is responsible for tolerance to cell-associated antigens. J Immunol. 2009;182:4127-36 pubmed publisher
Idoyaga J, Suda N, Suda K, Park C, Steinman R. Antibody to Langerin/CD207 localizes large numbers of CD8alpha+ dendritic cells to the marginal zone of mouse spleen. Proc Natl Acad Sci U S A. 2009;106:1524-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD207 (Langerin) Monoclonal Antibody (eBioL31), eBioscience

Catalog # :

14-2075-37

Quantity :

2 mg

Price :

US 1474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 ug/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1 ug/test

Species :

Mouse

Clone :

eBioL31

Isotype :

IgG2a

Storage :

4 C

Description :

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1 ug/test

Aliases :

CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913