CD207 (Langerin) Monoclonal Antibody (eBioRMUL.2), eBioscience™ | Invitrogen 14-2073-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD207 (Langerin) Monoclonal Antibody (eBioRMUL.2), eBioscience™

catalog :

14-2073-95

quantity :

10 mg

price :

US 3000.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBioRMUL.2

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

citations: 10

Reference
Jatana S, Palmer B, Phelan S, Gelein R, Delouise L. In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation. Part Fibre Toxicol. 2017;14:12 pubmed publisher
Brocks T, Fedorchenko O, Schliermann N, Stein A, Moll U, Seegobin S, et al. Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin. FASEB J. 2017;31:526-543 pubmed publisher
Joost S, Zeisel A, Jacob T, Sun X, La Manno G, Lönnerberg P, et al. Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity. Cell Syst. 2016;3:221-237.e9 pubmed publisher
Chen Q, Li R, Zhao X, Liang B, Ma S, Li Z, et al. Prevention of ultraviolet radiation?induced immunosuppression by sunscreen in Candida albicans?induced delayed?type hypersensitivity. Mol Med Rep. 2016;14:202-8 pubmed publisher
Lewis J, BÃ¼rgler C, Freudzon M, Golubets K, Gibson J, Filler R, et al. Langerhans Cells Facilitate UVB-Induced Epidermal Carcinogenesis. J Invest Dermatol. 2015;135:2824-2833 pubmed publisher
Yoo J, MANICONE A, McGuire J, Wang Y, Parks W. Systemic sensitization with the protein allergen ovalbumin augments local sensitization in atopic dermatitis. J Inflamm Res. 2014;7:29-38 pubmed publisher
Fukunaga A, Khaskhely N, Ma Y, Sreevidya C, Taguchi K, Nishigori C, et al. Langerhans cells serve as immunoregulatory cells by activating NKT cells. J Immunol. 2010;185:4633-40 pubmed publisher
Idoyaga J, Suda N, Suda K, Park C, Steinman R. Antibody to Langerin/CD207 localizes large numbers of CD8alpha+ dendritic cells to the marginal zone of mouse spleen. Proc Natl Acad Sci U S A. 2009;106:1524-9 pubmed publisher
Molinero L, Zhou P, Wang Y, Harlin H, Kee B, Abraham C, et al. Epidermal Langerhans cells promote skin allograft rejection in mice with NF-kappa B-impaired T cells. Am J Transplant. 2008;8:21-31 pubmed
Doepping S, Funk C, Habenicht A, Spanbroek R. Selective 5-lipoxygenase expression in Langerhans cells and impaired dendritic cell migration in 5-LO-deficient mice reveal leukotriene action in skin. J Invest Dermatol. 2007;127:1692-700 pubmed

product information

Product Type :

Antibody

Product Name :

CD207 (Langerin) Monoclonal Antibody (eBioRMUL.2), eBioscience™

Catalog # :

14-2073-95

Quantity :

10 mg

Price :

US 3000.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay-Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay-Dependent, Western Blot: 2 µg/mL

Species :

Mouse

Clone :

eBioRMUL.2

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay-Dependent, Western Blot: 2 µg/mL

Aliases :

CD 207 antigen; Cd207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; Clec4k; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913