CD197 (CCR7) Monoclonal Antibody (3D12), eBioscience | Invitrogen 14-1979-95 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD197 (CCR7) Monoclonal Antibody (3D12), eBioscience

catalog :

14-1979-95

quantity :

10 mg

price :

US 3430.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

3D12

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 27

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 2e	Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
flow cytometry; human; loading ...; fig 4b	Liu G, Yu Y, Feng F, Zhu P, Zhang H, Zhang D, et al. Human CD8+CD28- T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo. BMC Immunol. 2020;21:23 pubmed publisher
	Gao F, Wang H, Li X, Guo F, Yuan Y, Wang X, et al. Alteration of the Immune Microenvironment in HBsAg and HBeAg Dual-Positive Pregnant Women Presenting a High HBV Viral Load. J Inflamm Res. 2021;14:5619-5632 pubmed publisher
	Agalave N, Mody P, Szabo Pardi T, Jeong H, Burton M. Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy. Front Immunol. 2021;12:642420 pubmed publisher
	Zou Y, Liang J, Li D, Fang J, Wang L, Wang J, et al. Application of the chemokine-chemokine receptor axis increases the tumor-targeted migration ability of cytokine-induced killer cells in patients with colorectal cancer. Oncol Lett. 2020;20:123-134 pubmed publisher
	de Macedo Abdo L, Barros L, Saldanha Viegas M, Vieira Codeço Marques L, de Sousa Ferreira P, Chicaybam L, et al. Development of CAR-T cell therapy for B-ALL using a point-of-care approach. Oncoimmunology. 2020;9:1752592 pubmed publisher
	Pahk K, Shin C, Bae I, Yang Y, Kim S, Pahk K, et al. Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers. Sci Rep. 2019;9:9050 pubmed publisher
	Jarrell J, Twite A, Lau K, Kashani M, Lievano A, Acevedo J, et al. Intracellular delivery of mRNA to human primary T cells with microfluidic vortex shedding. Sci Rep. 2019;9:3214 pubmed publisher
	Jiao X, Shu G, Liu H, Zhang Q, Ma Z, Ren C, et al. The Diagnostic Value of Chemokine/Chemokine Receptor Pairs in Hepatocellular Carcinoma and Colorectal Liver Metastasis. J Histochem Cytochem. 2019;67:299-308 pubmed publisher
	Zhao X, Tang X, Guo N, An Y, Chen X, Shi C, et al. Biochanin a Enhances the Defense Against Salmonella enterica Infection Through AMPK/ULK1/mTOR-Mediated Autophagy and Extracellular Traps and Reversing SPI-1-Dependent Macrophage (MΦ) M2 Polarization. Front Cell Infect Microbiol. 2018;8:318 pubmed publisher
	Jung J, Choi B, Sayeed H, Suh C, Kim Y, Kim H, et al. Characteristic patterns of HLA presentation and T cell differentiation in adult-onset Still's disease. Int J Immunopathol Pharmacol. 2018;32:2058738418791284 pubmed publisher
	Wallin E, Hill D, Linterman M, Wood K. The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells. Front Immunol. 2018;9:1184 pubmed publisher
	McFarlin B, Venable A, Carpenter K, Henning A, Ogenstad S. Oral Supplementation with Baker's Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise. Front Physiol. 2017;8:786 pubmed publisher
	Pilling D, Galvis Carvajal E, Karhadkar T, Cox N, Gomer R. Monocyte differentiation and macrophage priming are regulated differentially by pentraxins and their ligands. BMC Immunol. 2017;18:30 pubmed publisher
	Yiwen Z, Shilin G, Yingshi C, Lishi S, Baohong L, Chao L, et al. Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy. Oncotarget. 2016;7:77732-77748 pubmed publisher
	Romano A, Hou X, Sertorio M, Dessein H, Cabantous S, Oliveira P, et al. FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly. PLoS Negl Trop Dis. 2016;10:e0004306 pubmed publisher
	Van Eyck L, De Somer L, Pombal D, Bornschein S, Frans G, Humblet Baron S, et al. Brief Report: IFIH1 Mutation Causes Systemic Lupus Erythematosus With Selective IgA Deficiency. Arthritis Rheumatol. 2015;67:1592-7 pubmed publisher
	Jacquelin B, Petitjean G, Kunkel D, Liovat A, Jochems S, Rogers K, et al. Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection. PLoS Pathog. 2014;10:e1004241 pubmed publisher
	Hartmann N, Giese N, Giese T, Poschke I, Offringa R, Werner J, et al. Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer. Clin Cancer Res. 2014;20:3422-33 pubmed publisher
	Till S, Raynsford E, Reynolds C, Quigley K, Grzybowska Kowalczyk A, Saggar L, et al. Peptide-induced immune regulation by a promiscuous and immunodominant CD4T-cell epitope of Timothy grass pollen: a role of Cbl-b and Itch in regulation. Thorax. 2014;69:335-45 pubmed publisher
	Miles B, Zakhary I, El Awady A, Scisci E, CARRION J, O Neill J, et al. Secondary lymphoid organ homing phenotype of human myeloid dendritic cells disrupted by an intracellular oral pathogen. Infect Immun. 2014;82:101-11 pubmed publisher
	Wijewardana V, Kristoff J, Xu C, Ma D, Haret Richter G, Stock J, et al. Kinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infections. PLoS Pathog. 2013;9:e1003600 pubmed publisher
	Himmel M, Macdonald K, Garcia R, Steiner T, Levings M. Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans. J Immunol. 2013;190:2001-8 pubmed publisher
	Male V, Sharkey A, Masters L, Kennedy P, Farrell L, Moffett A. The effect of pregnancy on the uterine NK cell KIR repertoire. Eur J Immunol. 2011;41:3017-27 pubmed publisher
	Huntington N, Alves N, Legrand N, Lim A, Strick Marchand H, Mention J, et al. IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo. Proc Natl Acad Sci U S A. 2011;108:6217-22 pubmed publisher
	Kwajah M M S, Schwarz H. CD137 ligand signaling induces human monocyte to dendritic cell differentiation. Eur J Immunol. 2010;40:1938-49 pubmed publisher
	Riz I, Hawley T, Johnston H, Hawley R. Role of TLX1 in T-cell acute lymphoblastic leukaemia pathogenesis. Br J Haematol. 2009;145:140-3 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD197 (CCR7) Monoclonal Antibody (3D12), eBioscience

Catalog # :

14-1979-95

Quantity :

10 mg

Price :

US 3430.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Paraffin): Assay-Dependent

Species :

Human

Clone :

3D12

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. CCR7 was identified to be induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. CCR7 is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries. Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Paraffin): Assay-Dependent

Aliases :

BLR2; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; C-C chemokine receptor type 7; C-C CKR-7; C-C motif chemokine receptor 7; CC-CKR-7; CCR7; CCR-7; CD197; CDw197; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; Cmkbr7; EBI1; Ebi1h; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor

more info or order :

Invitrogen product webpage