CD177 Monoclonal Antibody (MEM-166 (MEM166)), eBioscience | Invitrogen 14-1779-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD177 Monoclonal Antibody (MEM-166 (MEM166)), eBioscience

catalog :

14-1779-82

quantity :

100 ug

price :

US 148.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-166 (MEM166)

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

citations: 3

Reference
Kim Y, Shin J, Lee S, Chung W, Lee Y, Choi B, et al. Membrane-bound proteinase 3 and PAR2 mediate phagocytosis of non-opsonized bacteria in human neutrophils. Mol Immunol. 2011;48:1966-74 pubmed publisher
Jankowska A, Szpurka H, Calabro M, Mohan S, Schade A, Clemente M, et al. Loss of expression of neutrophil proteinase-3: a factor contributing to thrombotic risk in paroxysmal nocturnal hemoglobinuria. Haematologica. 2011;96:954-62 pubmed publisher
Kissel K, Santoso S, Hofmann C, Stroncek D, Bux J. Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immune neutropenias and transfusion reactions. Eur J Immunol. 2001;31:1301-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD177 Monoclonal Antibody (MEM-166 (MEM166)), eBioscience

Catalog # :

14-1779-82

Quantity :

100 ug

Price :

US 148.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 ug/test, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

MEM-166 (MEM166)

Isotype :

IgG1, kappa

Storage :

4 C

Description :

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181