CD171 Monoclonal Antibody (eBio5G3 (5G3)), eBioscience | Invitrogen 14-1719-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD171 Monoclonal Antibody (eBio5G3 (5G3)), eBioscience

catalog :

14-1719-82

quantity :

100 µg

price :

US 306.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eBio5G3 (5G3)

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1	Valentiner U, Knips J, Pries R, Clauditz T, Münscher A, Sauter G, et al. Selectin Binding Sites Are Involved in Cell Adhesive Properties of Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2019;11: pubmed publisher
flow cytometry; human; fig st1	Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
	Winston C, Sukreet S, Lynch H, Lee V, Wilcock D, Nelson P, et al. Evaluation of blood-based, extracellular vesicles as biomarkers for aging-related TDP-43 pathology. Alzheimers Dement (Amst). 2022;14:e12365 pubmed publisher
	Burrows K, Figueroa Hall L, Kuplicki R, Stewart J, Alarbi A, Ramesh R, et al. Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial. Sci Rep. 2022;12:861 pubmed publisher
	You Y, Muraoka S, Jedrychowski M, Hu J, McQuade A, Young Pearse T, et al. Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain. J Extracell Vesicles. 2022;11:e12183 pubmed publisher
	Delgado Peraza F, Nogueras Ortiz C, Volpert O, Liu D, Goetzl E, Mattson M, et al. Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease. Cells. 2021;10: pubmed publisher
	Nasca C, Dobbin J, Bigio B, Watson K, De Angelis P, Kautz M, et al. Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance. Mol Psychiatry. 2021;26:5140-5149 pubmed publisher
	Lee E, Winston Gray C, Barlow J, Rissman R, Jeste D. Plasma Levels of Neuron- and Astrocyte-Derived Exosomal Amyloid Beta1-42, Amyloid Beta1-40, and Phosphorylated Tau Levels in Schizophrenia Patients and Non-psychiatric Comparison Subjects: Relationships With Cognitive Functioning and Psychopathology. Front Psychiatry. 2020;11:532624 pubmed publisher
	Er E, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2018;20:966-978 pubmed publisher
	Balaian L, Moehler T, Montgomery A. The human neural cell adhesion molecule L1 functions as a costimulatory molecule in T cell activation. Eur J Immunol. 2000;30:938-43 pubmed

product information

Product Type :

Antibody

Product Name :

CD171 Monoclonal Antibody (eBio5G3 (5G3)), eBioscience

Catalog # :

14-1719-82

Quantity :

100 µg

Price :

US 306.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

eBio5G3 (5G3)

Isotype :

IgG2a

Storage :

4° C

Description :

L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

antigen identified by monoclonal antibody R1; CAML1; CD 171; CD171; CD171 molecule; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1CAM; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1

more info or order :

Invitrogen product webpage