CD144 (VE-cadherin) Monoclonal Antibody (eBioBV14 (BV14)), eBioscience | Invitrogen 14-1442-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD144 (VE-cadherin) Monoclonal Antibody (eBioBV14 (BV14)), eBioscience

catalog :

14-1442-82

quantity :

100 ug

price :

US 250.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBioBV14 (BV14)

reactivity :

mouse

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 5

Reference
Herrera C, Voisin M, Escalante T, Rucavado A, Nourshargh S, Gutierrez J. Effects of PI and PIII Snake Venom Haemorrhagic Metalloproteinases on the Microvasculature: A Confocal Microscopy Study on the Mouse Cremaster Muscle. PLoS ONE. 2016;11:e0168643 pubmed publisher
Yoshimoto M, Porayette P, Glosson N, Conway S, Carlesso N, Cardoso A, et al. Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood. 2012;119:5706-14 pubmed publisher
Crosby C, Fleming P, Argraves W, Corada M, Zanetta L, Dejana E, et al. VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly. Blood. 2005;105:2771-6 pubmed
Liao F, Li Y, O Connor W, Zanetta L, Bassi R, Santiago A, et al. Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis. Cancer Res. 2000;60:6805-10 pubmed
Corada M, Mariotti M, Thurston G, Smith K, Kunkel R, Brockhaus M, et al. Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A. 1999;96:9815-20 pubmed

product information

Product Type :

Antibody

Product Name :

CD144 (VE-cadherin) Monoclonal Antibody (eBioBV14 (BV14)), eBioscience

Catalog # :

14-1442-82

Quantity :

100 ug

Price :

US 250.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 2 ug/mL

Species :

Mouse

Clone :

eBioBV14 (BV14)

Isotype :

IgG2b

Storage :

4 C

Description :

VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.

Format :

Liquid

Applications w/Dilutions :

Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 2 ug/mL

Aliases :

7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD