CD138 (Syndecan-1) Monoclonal Antibody (DL-101), eBioscience | Invitrogen 14-1389-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD138 (Syndecan-1) Monoclonal Antibody (DL-101), eBioscience

catalog :

14-1389-82

quantity :

100 µg

price :

US 150.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DL-101

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:40	Steinsbø Ø, Henry Dunand C, Huang M, Mesin L, Salgado Ferrer M, Lundin K, et al. Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells. Nat Commun. 2014;5:4041 pubmed publisher
	Akidil E, Albanese M, Buschle A, Ruhle A, Pich D, Keppler O, et al. Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection. PLoS Pathog. 2021;17:e1009117 pubmed publisher
	Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, et al. Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus. Nat Commun. 2018;9:1136 pubmed publisher
	Schibler J, Tomanek Chalkley A, Reedy J, Zhan F, Spitz D, Schultz M, et al. Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells. PLoS ONE. 2016;11:e0167323 pubmed publisher
	Kikuchi J, Koyama D, Wada T, Izumi T, Hofgaard P, Bogen B, et al. Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma. J Clin Invest. 2015;125:4375-90 pubmed publisher
	Neumann B, Klippert A, Raue K, Sopper S, Stahl Hennig C. Characterization of B and plasma cells in blood, bone marrow, and secondary lymphoid organs of rhesus macaques by multicolor flow cytometry. J Leukoc Biol. 2015;97:19-30 pubmed publisher
	Itoua Maïga R, Lemieux J, Roy A, Simard C, Néron S. Flow cytometry assessment of in vitro generated CD138+ human plasma cells. Biomed Res Int. 2014;2014:536482 pubmed publisher
	Brusilovsky M, Cordoba M, Rosental B, Hershkovitz O, Andrake M, Pecherskaya A, et al. Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses. J Immunol. 2013;191:5256-67 pubmed publisher
	Cantor J, Browne C, Ruppert R, Feral C, Fassler R, Rickert R, et al. CD98hc facilitates B cell proliferation and adaptive humoral immunity. Nat Immunol. 2009;10:412-9 pubmed publisher
	Mosheimer B, Kaneider N, Feistritzer C, Djanani A, Sturn D, Patsch J, et al. Syndecan-1 is involved in osteoprotegerin-induced chemotaxis in human peripheral blood monocytes. J Clin Endocrinol Metab. 2005;90:2964-71 pubmed
	Fitzgerald M, Wang Z, Park P, Murphy G, Bernfield M. Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase. J Cell Biol. 2000;148:811-24 pubmed
	Kainulainen V, Wang H, Schick C, Bernfield M. Syndecans, heparan sulfate proteoglycans, maintain the proteolytic balance of acute wound fluids. J Biol Chem. 1998;273:11563-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD138 (Syndecan-1) Monoclonal Antibody (DL-101), eBioscience

Catalog # :

14-1389-82

Quantity :

100 µg

Price :

US 150.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 µg/test, Immunohistochemistry (Frozen): Assay-Dependent

Species :

Human

Clone :

DL-101

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin

more info or order :

Invitrogen product webpage