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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD106 (VCAM-1) Monoclonal Antibody (429), eBioscience
catalog :
14-1061-85
quantity :
500 µg
price :
US 280.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
429
reactivity :
mouse
application :
immunohistochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1e
Feng Y, Liao Y, Huang W, Lai X, Luo J, Du C, et al. Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis. Cell Death Dis. 2018;9:691 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7e
Zhang Y, Tech L, George L, Acs A, Durrett R, Hess H, et al. Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells. J Exp Med. 2018;215:1227-1243 pubmed publisher
  • flow cytometry; mouse; fig 7j
Danahy D, Anthony S, Jensen I, Hartwig S, Shan Q, Xue H, et al. Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells. PLoS Pathog. 2017;13:e1006569 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 7g
Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher
  • flow cytometry; mouse; loading ...; fig st1
Itkin T, Gur Cohen S, Spencer J, Schajnovitz A, Ramasamy S, Kusumbe A, et al. Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. 2016;532:323-8 pubmed publisher
  • flow cytometry; mouse; 1:100
Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 3a-c
Martin Blondel G, Pignolet B, Tietz S, Yshii L, Gebauer C, Périnat T, et al. Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin. Eur J Immunol. 2015;45:3302-12 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7b
  • immunohistochemistry; mouse; loading ...; fig s1e
Peske J, Thompson E, Gemta L, Baylis R, Fu Y, Engelhard V. Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity. Nat Commun. 2015;6:7114 pubmed publisher
Baluk P, McDonald D. Imaging Blood Vessels and Lymphatics in Mouse Trachea Wholemounts. Methods Mol Biol. 2022;2441:115-134 pubmed publisher
Zhang C, Gu X, Zhao G, Wang W, Shao J, Zhu J, et al. Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues. Ther Adv Chronic Dis. 2020;11:2040622320956429 pubmed publisher
Niethamer T, Stabler C, Leach J, Zepp J, Morley M, Babu A, et al. Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury. elife. 2020;9: pubmed publisher
Piao W, Xiong Y, Li L, Saxena V, Smith K, Hippen K, et al. Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration. Cell Rep. 2020;30:1052-1062.e5 pubmed publisher
Palhinha L, Liechocki S, Hottz E, Pereira J, de Almeida C, Moraes Vieira P, et al. Leptin Induces Proadipogenic and Proinflammatory Signaling in Adipocytes. Front Endocrinol (Lausanne). 2019;10:841 pubmed publisher
Deloch L, Rückert M, Fietkau R, Frey B, Gaipl U. Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints. Int J Mol Sci. 2018;19: pubmed publisher
Xie S, Li J, Chen H, Tan Y, Liu S, Zhang Y, et al. Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development. Cell Death Differ. 2018;25:1581-1597 pubmed publisher
Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
Xiong Y, Brinkman C, Famulski K, Mongodin E, Lord C, Hippen K, et al. A robust in vitro model for trans-lymphatic endothelial migration. Sci Rep. 2017;7:1633 pubmed publisher
Brinkman C, Iwami D, Hritzo M, Xiong Y, Ahmad S, Simon T, et al. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nat Commun. 2016;7:12021 pubmed publisher
Cheng L, Sullivan B, Retana L, Allen C, Liang H, Locksley R. IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function. J Exp Med. 2015;212:513-24 pubmed publisher
Harding M, Zhang K, Conly J, Kubes P. Neutrophil crawling in capillaries; a novel immune response to Staphylococcus aureus. PLoS Pathog. 2014;10:e1004379 pubmed publisher
Kaynar A, Yende S, Zhu L, Frederick D, Chambers R, Burton C, et al. Effects of intra-abdominal sepsis on atherosclerosis in mice. Crit Care. 2014;18:469 pubmed publisher
Haldar M, Kohyama M, So A, Kc W, Wu X, Briseño C, et al. Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell. 2014;156:1223-1234 pubmed publisher
Wu Z, Curaj A, Fokong S, Liehn E, Weber C, Lammers T, et al. Rhodamine-loaded intercellular adhesion molecule-1-targeted microbubbles for dual-modality imaging under controlled shear stresses. Circ Cardiovasc Imaging. 2013;6:974-81 pubmed publisher
Marchese M, Berdnikovs S, Cook Mills J. Distinct sites within the vascular cell adhesion molecule-1 (VCAM-1) cytoplasmic domain regulate VCAM-1 activation of calcium fluxes versus Rac1 during leukocyte transendothelial migration. Biochemistry. 2012;51:8235-46 pubmed publisher
de Oliveira Cipriano Torres D, Santos A, Silva A, de Moura P, Beltrão E, Peixoto C. Influence of fatty acids in maternal diet on atherogenesis in offspring of LDL receptor-deficient mice. Int J Clin Exp Med. 2012;5:56-63 pubmed
Savinov A, Wong F, Stonebraker A, Chervonsky A. Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. J Exp Med. 2003;197:643-56 pubmed
Kinashi T, St Pierre Y, Springer T. Expression of glycophosphatidylinositol-anchored and -non-anchored isoforms of vascular cell adhesion molecule 1 in murine stromal and endothelial cells. J Leukoc Biol. 1995;57:168-73 pubmed
product information
Product Type :
Antibody
Product Name :
CD106 (VCAM-1) Monoclonal Antibody (429), eBioscience
Catalog # :
14-1061-85
Quantity :
500 µg
Price :
US 280.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Neutralization: Assay-Dependent
Species :
Mouse
Clone :
429
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. The protein has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Neutralization: Assay-Dependent
Aliases :
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA