CD104 (Integrin beta 4) Monoclonal Antibody (439-9B), eBioscience | Invitrogen 14-1049-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD104 (Integrin beta 4) Monoclonal Antibody (439-9B), eBioscience

catalog :

14-1049-82

quantity :

100 µg

price :

US 140.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

439-9B

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...	Nguyen N, Bellile E, Thomas D, McHugh J, Rozek L, Virani S, et al. Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma. Head Neck. 2016;38:1074-84 pubmed publisher
	Qi L, Knifley T, Chen M, O Connor K. Integrin α6β4 requires plectin and vimentin for adhesion complex distribution and invasive growth. J Cell Sci. 2022;135: pubmed publisher
	Gabaev I, Williamson J, Crozier T, Schulz T, Lehner P. Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation. Cell Rep. 2020;33:108249 pubmed publisher
	Lee J, Dominguez A, Nam S, Stowers R, Qi L, Chaudhuri O. Identification of cell context-dependent YAP-associated proteins reveals β1 and β4 integrin mediate YAP translocation independently of cell spreading. Sci Rep. 2019;9:17188 pubmed publisher
	Bierie B, Pierce S, Kroeger C, Stover D, Pattabiraman D, Thiru P, et al. Integrin-?4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells. Proc Natl Acad Sci U S A. 2017;114:E2337-E2346 pubmed publisher
	Masugi Y, Yamazaki K, Emoto K, Effendi K, Tsujikawa H, Kitago M, et al. Upregulation of integrin Î²4 promotes epithelial-mesenchymal transition and is a novel prognostic marker in pancreatic ductal adenocarcinoma. Lab Invest. 2015;95:308-19 pubmed publisher
	Wansom D, Light E, Thomas D, Worden F, Prince M, Urba S, et al. Infiltrating lymphocytes and human papillomavirus-16--associated oropharyngeal cancer. Laryngoscope. 2012;122:121-7 pubmed publisher
	Simon Assmann P, Leberquier C, Molto N, Uezato T, Bouziges F, Kedinger M. Adhesive properties and integrin expression profiles of two colonic cancer populations differing by their spreading on laminin. J Cell Sci. 1994;107 ( Pt 3):577-87 pubmed
	Falcioni R, Sacchi A, Resau J, Kennel S. Monoclonal antibody to human carcinoma-associated protein complex: quantitation in normal and tumor tissue. Cancer Res. 1988;48:816-21 pubmed

product information

Product Type :

Antibody

Product Name :

CD104 (Integrin beta 4) Monoclonal Antibody (439-9B), eBioscience

Catalog # :

14-1049-82

Quantity :

100 µg

Price :

US 140.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human

Applications :

Flow Cytometry: 1 µg/test, Immunocytochemistry: 5 µg/ml, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

439-9B

Isotype :

IgG2b

Storage :

4° C

Description :

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Format :

Liquid

Applications w/Dilutions :

Aliases :

AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4

more info or order :

Invitrogen product webpage