CD100 (SEMA4D) Monoclonal Antibody (BMA12 (BMA-12)), eBioscience | Invitrogen 14-1001-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD100 (SEMA4D) Monoclonal Antibody (BMA12 (BMA-12)), eBioscience

catalog :

14-1001-82

quantity :

100 ug

price :

US 360.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

BMA12 (BMA-12)

reactivity :

mouse

application :

immunohistochemistry, immunoprecipitation, flow cytometry

citations: 3

Reference
Smith E, Shanks K, Lipsky M, DeTolla L, Keegan A, Chapoval S. Expression of neuroimmune semaphorins 4A and 4D and their receptors in the lung is enhanced by allergen and vascular endothelial growth factor. BMC Immunol. 2011;12:30 pubmed publisher
Zielonka M, Xia J, Friedel R, Offermanns S, Worzfeld T. A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system. Exp Cell Res. 2010;316:2477-86 pubmed publisher
Wang X, Kumanogoh A, Watanabe C, Shi W, Yoshida K, Kikutani H. Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responses. Blood. 2001;97:3498-504 pubmed

product information

Product Type :

Antibody

Product Name :

CD100 (SEMA4D) Monoclonal Antibody (BMA12 (BMA-12)), eBioscience

Catalog # :

14-1001-82

Quantity :

100 ug

Price :

US 360.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Mouse

Clone :

BMA12 (BMA-12)

Isotype :

IgG2a

Storage :

4 C

Description :

Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

A8; BB18; C9orf164; CD100; coll-4; GR3; M-Sema G; M-sema-G; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D; sema J; Sema4d; Semacl2; SEMAJ; semaphorin 4D; semaphorin H; semaphorin-4D; Semaphorin-C-like 2; semaphorin-J; Semcl2