CD93 (AA4.1) Monoclonal Antibody (R139), eBioscience™ | Invitrogen 14-0939-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD93 (AA4.1) Monoclonal Antibody (R139), eBioscience™

catalog :

14-0939-95

quantity :

10 mg

price :

US 3000

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

R139

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 15

Reference
Goiko M, de Bruyn J, Heit B. Short-Lived Cages Restrict Protein Diffusion in the Plasma Membrane. Sci Rep. 2016;6:34987 pubmed publisher
Cheng Y, Chikwava K, Wu C, Zhang H, Bhagat A, Pei D, et al. LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors. J Clin Invest. 2016;126:1267-81 pubmed publisher
Guye P, Ebrahimkhani M, Kipniss N, Velazquez J, Schoenfeld E, Kiani S, et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun. 2016;7:10243 pubmed publisher
Detre C, Yigit B, Keszei M, Castro W, Magelky E, Terhorst C. SAP modulates B cell functions in a genetic background-dependent manner. Immunol Lett. 2013;153:15-21 pubmed publisher
Zhong M, Veillette A. Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity. Mol Cell Biol. 2013;33:1223-32 pubmed publisher
Belnoue E, Tougne C, Rochat A, Lambert P, Pinschewer D, Siegrist C. Homing and adhesion patterns determine the cellular composition of the bone marrow plasma cell niche. J Immunol. 2012;188:1283-91 pubmed publisher
Hao Y, O Neill P, Naradikian M, Scholz J, Cancro M. A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood. 2011;118:1294-304 pubmed publisher
Tavares R, Turer E, Liu C, Advincula R, Scapini P, Rhee L, et al. The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. Immunity. 2010;33:181-91 pubmed publisher
Donovan E, Pelanda R, Torres R. S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development. Eur J Immunol. 2010;40:688-98 pubmed publisher
Frenzel A, Labi V, Chmelewskij W, Ploner C, Geley S, Fiegl H, et al. Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad. Blood. 2010;115:995-1005 pubmed publisher
Srinivasan L, Sasaki Y, Calado D, Zhang B, Paik J, Depinho R, et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell. 2009;139:573-86 pubmed publisher
Wang J, Chiu Y. Systemic hypoxia enhances exercise-mediated bactericidal and subsequent apoptotic responses in human neutrophils. J Appl Physiol (1985). 2009;107:1213-22 pubmed publisher
Saha S, Gonzalez J, Rosenfeld G, Keiser H, Peeva E. Prolactin alters the mechanisms of B cell tolerance induction. Arthritis Rheum. 2009;60:1743-52 pubmed publisher
Gross A, Lyandres J, Panigrahi A, Prak E, DeFranco A. Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance. J Immunol. 2009;182:5382-92 pubmed publisher
Chevrier S, Genton C, Kallies A, Karnowski A, Otten L, Malissen B, et al. CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche. Proc Natl Acad Sci U S A. 2009;106:3895-900 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD93 (AA4.1) Monoclonal Antibody (R139), eBioscience™

Catalog # :

14-0939-95

Quantity :

10 mg

Price :

US 3000

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Paraffin): 40 µg/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

R139

Isotype :

IgG2b

Storage :

4° C

Description :

The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Paraffin): 40 µg/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

6030404G09Rik; AA145088; Aa4; AA4.1; AW555904; C1q receptor; C1q receptor 1; C1q/MBL/SPA receptor; C1qR; C1qR(p); C1QR1; C1qrp; CD93; CD93 antigen; CD93 molecule; CDw93; Cell surface antigen AA4; Complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; Complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Ly-68; Lymphocyte antigen 68; Matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4