product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD90 (Thy-1) Monoclonal Antibody (eBio5E10 (5E10)), eBioscience
catalog :
14-0909-82
quantity :
100 µg
price :
US 241.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
eBio5E10 (5E10)
reactivity :
human, cat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 68
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1c
Luo B, Zhan Y, Luo M, Dong H, Liu J, Lin Y, et al. Engineering of α-PD-1 antibody-expressing long-lived plasma cells by CRISPR/Cas9-mediated targeted gene integration. Cell Death Dis. 2020;11:973 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...
Zakharova I, Zhiven M, Saaya S, Shevchenko A, Smirnova A, Strunov A, et al. Endothelial and smooth muscle cells derived from human cardiac explants demonstrate angiogenic potential and suitable for design of cell-containing vascular grafts. J Transl Med. 2017;15:54 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 4 A-i
Farup J, De Lisio M, Rahbek S, Bjerre J, Vendelbo M, Boppart M, et al. Pericyte response to contraction mode-specific resistance exercise training in human skeletal muscle. J Appl Physiol (1985). 2015;119:1053-63 pubmed publisher
  • flow cytometry; cat; 1:50; tbl 3
Gómez M, Qin Q, Biancardi M, Galiguis J, Dumas C, MacLean R, et al. Characterization and Multilineage Differentiation of Domestic and Black-Footed Cat Mesenchymal Stromal/Stem Cells from Abdominal and Subcutaneous Adipose Tissue. Cell Reprogram. 2015;17:376-92 pubmed publisher
  • flow cytometry; human; fig s4
James S, Fox J, Afsari F, Lee J, Clough S, Knight C, et al. Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes. Stem Cell Reports. 2015;4:1004-15 pubmed publisher
  • immunohistochemistry - frozen section; human; 1 ug/ml; fig 3a
Weston C, Shepherd E, Claridge L, Rantakari P, Curbishley S, Tomlinson J, et al. Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. J Clin Invest. 2015;125:501-20 pubmed publisher
  • flow cytometry; human; loading ...; fig 2c
Byrne S, Ortiz L, Mali P, Aach J, Church G. Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells. Nucleic Acids Res. 2015;43:e21 pubmed publisher
  • flow cytometry; human; tbl 2
Ghebeh H, Sleiman G, Manogaran P, Al Mazrou A, Barhoush E, Al Mohanna F, et al. Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers. BMC Cancer. 2013;13:289 pubmed publisher
Billeskov T, Jensen J, Jessen N, Farup J. Fluorescence-activated cell sorting and phenotypic characterization of human fibro-adipogenic progenitors. STAR Protoc. 2023;4:102008 pubmed publisher
Mavinga M, Palmier M, R xe9 my M, Jeanni xe8 re C, Lenoir S, Rey S, et al. The Journey of SCAPs (Stem Cells from Apical Papilla), from Their Native Tissue to Grafting: Impact of Oxygen Concentration. Cells. 2022;11: pubmed publisher
Montalb xe1 n Hern xe1 ndez K, Casado S xe1 nchez C, Avenda xf1 o Ortiz J, Casalvilla Due xf1 as J, Bonel P xe9 rez G, Prado Montero J, et al. Fused Cells between Human-Adipose-Derived Mesenchymal Stem Cells and Monocytes Keep Stemness Properties and Acquire High Mobility. Int J Mol Sci. 2022;23: pubmed publisher
O Donnell B, Monjure T, Al Ghadban S, Ives C, L Ecuyer M, Rhee C, et al. Aberrant Expression of COX-2 and FOXG1 in Infrapatellar Fat Pad-Derived ASCs from Pre-Diabetic Donors. Cells. 2022;11: pubmed publisher
Mu R, Chen B, Bi B, Yu H, Liu J, Li J, et al. LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling. Int J Med Sci. 2022;19:1307-1319 pubmed publisher
Liu P, Zhang Q, Mi J, Wang S, Xu Q, Zhuang D, et al. Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246. Stem Cell Res Ther. 2022;13:89 pubmed publisher
Jiang W, Zhang J, Zhang X, Fan C, Huang J. VAP-PLGA microspheres (VAP-PLGA) promote adipose-derived stem cells (ADSCs)-induced wound healing in chronic skin ulcers in mice via PI3K/Akt/HIF-1α pathway. Bioengineered. 2021;12:10264-10284 pubmed publisher
Fei D, Xia Y, Zhai Q, Wang Y, Zhou F, Zhao W, et al. Exosomes Regulate Interclonal Communication on Osteogenic Differentiation Among Heterogeneous Osteogenic Single-Cell Clones Through PINK1/Parkin-Mediated Mitophagy. Front Cell Dev Biol. 2021;9:687258 pubmed publisher
Chen C, Huang X, Zhu W, Ding C, Huang P, Li R. TRPA1 triggers hyperalgesia and inflammation after tooth bleaching. Sci Rep. 2021;11:17418 pubmed publisher
Li Y, Shi G, Han Y, Shang H, Li H, Liang W, et al. Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model. Stem Cell Res Ther. 2021;12:407 pubmed publisher
Li Z, Wang Z, Dinh P, Zhu D, Popowski K, Lutz H, et al. Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19. Nat Nanotechnol. 2021;16:942-951 pubmed publisher
Babaei A, Bannazadeh Baghi H, Nezhadi A, Jamalpoor Z. In Vitro Anti-cancer Activity of Adipose-Derived Mesenchymal Stem Cells Increased after Infection with Oncolytic Reovirus. Adv Pharm Bull. 2021;11:361-370 pubmed publisher
Gasiūnienė M, Valatkaitė E, Navakauskaitė A, Navakauskiene R. The Effect of Angiotensin II, Retinoic Acid, EGCG, and Vitamin C on the Cardiomyogenic Differentiation Induction of Human Amniotic Fluid-Derived Mesenchymal Stem Cells. Int J Mol Sci. 2020;21: pubmed publisher
Zhao A, Shah K, Freitag J, Cromer B, Sumer H. Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia. Stem Cells Int. 2020;2020:8898221 pubmed publisher
Sun L, Zhu W, Zhao P, Zhang J, Lu Y, Zhu Y, et al. Down-Regulated Exosomal MicroRNA-221 - 3p Derived From Senescent Mesenchymal Stem Cells Impairs Heart Repair. Front Cell Dev Biol. 2020;8:263 pubmed publisher
Deng Q, Huang S, Wen J, Jiao Y, Su X, Shi G, et al. PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice. Stem Cell Res Ther. 2020;11:143 pubmed publisher
Huang J, Wang Y, Lo S, Tseng L, Chen D, Wu Y, et al. Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer. Cancers (Basel). 2019;12: pubmed publisher
Gambardella L, McManus S, Moignard V, Sebukhan D, Delaune A, Andrews S, et al. BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium. Development. 2019;146: pubmed publisher
Fan C, Ji Q, Zhang C, Xu S, Sun H, Li Z. TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production. Mol Med Rep. 2019;20:3123-3130 pubmed publisher
Yu B, Li Q, Zhou M. LPS‑induced upregulation of the TLR4 signaling pathway inhibits osteogenic differentiation of human periodontal ligament stem cells under inflammatory conditions. Int J Mol Med. 2019;43:2341-2351 pubmed publisher
Ji S, Wu C, Tong L, Wang L, Zhou J, Chen C, et al. Better therapeutic potential of bone marrow-derived mesenchymal stem cells compared with chorionic villi-derived mesenchymal stem cells in airway injury model. Regen Med. 2019;14:165-177 pubmed publisher
Yan N, Xu J, Zhao C, Wu Y, Gao F, Li C, et al. Human umbilical cord-derived mesenchymal stem cells ameliorate the enteropathy of food allergies in mice. Exp Ther Med. 2018;16:4445-4456 pubmed publisher
Compeer E, Kraus F, Ecker M, Redpath G, Amiezer M, Rother N, et al. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun. 2018;9:1597 pubmed publisher
Ventura Ferreira M, Bienert M, Muller K, Rath B, Goecke T, Opländer C, et al. Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta. Stem Cell Res Ther. 2018;9:28 pubmed publisher
Philippeos C, Telerman S, Oulès B, Pisco A, Shaw T, Elgueta R, et al. Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations. J Invest Dermatol. 2018;138:811-825 pubmed publisher
Yuan C, Pu L, He Z, Wang J. BNIP3/Bcl-2-mediated apoptosis induced by cyclic tensile stretch in human cartilage endplate-derived stem cells. Exp Ther Med. 2018;15:235-241 pubmed publisher
Zhang K, Che S, Su Z, Zheng S, Zhang H, Yang S, et al. CD90 promotes cell migration, viability and sphere?forming ability of hepatocellular carcinoma cells. Int J Mol Med. 2018;41:946-954 pubmed publisher
Lu T, Zong M, Fan S, Lu Y, Yu S, Fan L. Thioredoxin 1 is associated with the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes. Clin Rheumatol. 2018;37:117-125 pubmed publisher
Liu Y, Yang H, Wen Y, Li B, Zhao Y, Xing J, et al. Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative Stress. Int J Mol Sci. 2017;18: pubmed publisher
Li J, Mao Q, He J, She H, Zhang Z, Yin C. Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism. Stem Cell Res Ther. 2017;8:55 pubmed publisher
Webber B, Osborn M, McElroy A, Twaroski K, Lonetree C, Defeo A, et al. CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa. NPJ Regen Med. 2016;1: pubmed publisher
Yao Y, Deng Q, Song W, Zhang H, Li Y, Yang Y, et al. MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia. Stem Cell Reports. 2016;7:249-62 pubmed publisher
Nakamura T, Hosoyama T, Kawamura D, Takeuchi Y, Tanaka Y, Samura M, et al. Influence of aging on the quantity and quality of human cardiac stem cells. Sci Rep. 2016;6:22781 pubmed publisher
Zhu N, Wang H, Wang B, Wei J, Shan W, Feng J, et al. A Member of the Nuclear Receptor Superfamily, Designated as NR2F2, Supports the Self-Renewal Capacity and Pluripotency of Human Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells Int. 2016;2016:5687589 pubmed publisher
Gargus M, Niu C, Vallone J, Binkley J, Rubin D, Shaker A. Human esophageal myofibroblasts secrete proinflammatory cytokines in response to acid and Toll-like receptor 4 ligands. Am J Physiol Gastrointest Liver Physiol. 2015;308:G904-23 pubmed
Asmuth D, Pinchuk I, Wu J, Vargas G, Chen X, Mann S, et al. Role of intestinal myofibroblasts in HIV-associated intestinal collagen deposition and immune reconstitution following combination antiretroviral therapy. AIDS. 2015;29:877-88 pubmed publisher
Feng Y, Zhu M, Dangelmajer S, Lee Y, Wijesekera O, Castellanos C, et al. Hypoxia-cultured human adipose-derived mesenchymal stem cells are non-oncogenic and have enhanced viability, motility, and tropism to brain cancer. Cell Death Dis. 2014;5:e1567 pubmed publisher
Yuan S, Guo Y, Zhou X, Shen W, Chen H. PDGFR-? (+) perivascular cells from infantile hemangioma display the features of mesenchymal stem cells and show stronger adipogenic potential in vitro and in vivo. Int J Clin Exp Pathol. 2014;7:2861-70 pubmed
Mohanty N, Gulati B, Kumar R, Gera S, Kumar P, Somasundaram R, et al. Immunophenotypic characterization and tenogenic differentiation of mesenchymal stromal cells isolated from equine umbilical cord blood. In Vitro Cell Dev Biol Anim. 2014;50:538-48 pubmed publisher
Mendez J, Ghaedi M, Steinbacher D, Niklason L. Epithelial cell differentiation of human mesenchymal stromal cells in decellularized lung scaffolds. Tissue Eng Part A. 2014;20:1735-46 pubmed publisher
Indumathi S, Harikrishnan R, Rajkumar J, Dhanasekaran M. Immunophenotypic comparison of heterogenous non-sorted versus sorted mononuclear cells from human umbilical cord blood: a novel cell enrichment approach. Cytotechnology. 2015;67:107-14 pubmed publisher
Kono S, Kazama T, Kano K, Harada K, Uechi M, Matsumoto T. Phenotypic and functional properties of feline dedifferentiated fat cells and adipose-derived stem cells. Vet J. 2014;199:88-96 pubmed publisher
Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
Quimby J, WEBB T, Habenicht L, Dow S. Safety and efficacy of intravenous infusion of allogeneic cryopreserved mesenchymal stem cells for treatment of chronic kidney disease in cats: results of three sequential pilot studies. Stem Cell Res Ther. 2013;4:48 pubmed publisher
Rosu Myles M, McCully J, Fair J, Mehic J, Menendez P, Rodriguez R, et al. The globoseries glycosphingolipid SSEA-4 is a marker of bone marrow-derived clonal multipotent stromal cells in vitro and in vivo. Stem Cells Dev. 2013;22:1387-97 pubmed publisher
Liu R, Ratajczak M. Enumeration of very small embryonic-like stem cells in peripheral blood. Methods Mol Biol. 2012;904:207-19 pubmed publisher
Kollert F, Christoph S, Probst C, Budweiser S, Bannert B, Binder M, et al. Soluble CD90 as a potential marker of pulmonary involvement in systemic sclerosis. Arthritis Care Res (Hoboken). 2013;65:281-7 pubmed publisher
Rosu Myles M, She Y, Fair J, Muradia G, Mehic J, Menendez P, et al. Identification of a candidate proteomic signature to discriminate multipotent and non-multipotent stromal cells. PLoS ONE. 2012;7:e38954 pubmed publisher
Danova Alt R, Heider A, Egger D, Cross M, Alt R. Very small embryonic-like stem cells purified from umbilical cord blood lack stem cell characteristics. PLoS ONE. 2012;7:e34899 pubmed publisher
Iqbal S, Sidgwick G, Bayat A. Identification of fibrocytes from mesenchymal stem cells in keloid tissue: a potential source of abnormal fibroblasts in keloid scarring. Arch Dermatol Res. 2012;304:665-71 pubmed publisher
Bray L, George K, Hutmacher D, Chirila T, Harkin D. A dual-layer silk fibroin scaffold for reconstructing the human corneal limbus. Biomaterials. 2012;33:3529-38 pubmed publisher
Meyer Zu Hörste M, Ströher E, Berchner Pfannschmidt U, Schmitz Spanke S, Pink M, Gothert J, et al. A novel mechanism involved in the pathogenesis of Graves ophthalmopathy (GO): clathrin is a possible targeting molecule for inhibiting local immune response in the orbit. J Clin Endocrinol Metab. 2011;96:E1727-36 pubmed publisher
Frei C, Opitz I, Soltermann A, Fischer B, Moura U, Rehrauer H, et al. Pleural mesothelioma side populations have a precursor phenotype. Carcinogenesis. 2011;32:1324-32 pubmed publisher
Quimby J, WEBB T, Gibbons D, Dow S. Evaluation of intrarenal mesenchymal stem cell injection for treatment of chronic kidney disease in cats: a pilot study. J Feline Med Surg. 2011;13:418-26 pubmed publisher
Bigley V, Haniffa M, Doulatov S, Wang X, Dickinson R, McGovern N, et al. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. J Exp Med. 2011;208:227-34 pubmed publisher
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Mallam E, Kemp K, Wilkins A, Rice C, Scolding N. Characterization of in vitro expanded bone marrow-derived mesenchymal stem cells from patients with multiple sclerosis. Mult Scler. 2010;16:909-18 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
CD90 (Thy-1) Monoclonal Antibody (eBio5E10 (5E10)), eBioscience
Catalog # :
14-0909-82
Quantity :
100 µg
Price :
US 241.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
Species :
Human
Clone :
eBio5E10 (5E10)
Isotype :
IgG1, kappa
Storage :
4° C
Description :
CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
Aliases :
CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA