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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD90.2 (Thy-1.2) Monoclonal Antibody (30-H12), eBioscience
catalog :
14-0903-85
quantity :
500 µg
price :
US 197.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
30-H12
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 56
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s3
Safya H, Mellouk A, Legrand J, Le Gall S, Benbijja M, Kanellopoulos Langevin C, et al. Variations in Cellular Responses of Mouse T Cells to Adenosine-5'-Triphosphate Stimulation Do Not Depend on P2X7 Receptor Expression Levels but on Their Activation and Differentiation Stage. Front Immunol. 2018;9:360 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1f
Huang Y, Mao K, Chen X, Sun M, Kawabe T, Li W, et al. S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense. Science. 2018;359:114-119 pubmed publisher
  • flow cytometry; mouse; 0.25 ug/ml; loading ...; fig 1a
Yamamura K, Uruno T, Shiraishi A, Tanaka Y, Ushijima M, Nakahara T, et al. The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. Nat Commun. 2017;8:13946 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Guo L, Huang Y, Chen X, Hu Li J, Urban J, Paul W. Innate immunological function of TH2 cells in vivo. Nat Immunol. 2015;16:1051-9 pubmed publisher
  • flow cytometry; mouse
Xin L, Jiang T, Kinder J, Ertelt J, Way S. Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna(Dhe) mice. Aging Cell. 2015;14:1122-6 pubmed publisher
  • flow cytometry; mouse
Powell N, Walker A, Stolarczyk E, Canavan J, Gökmen M, Marks E, et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity. 2012;37:674-84 pubmed publisher
Xiao K, Yang L, Xie W, Gao X, Huang R, Xie M. Bcl-xL mutant promotes cartilage differentiation of BMSCs by upregulating TGF-β/BMP expression levels. Exp Ther Med. 2021;22:736 pubmed publisher
Crouse B, Robinson C, Huseby Kelcher A, Laudenbach M, Abrahante J, Pravetoni M. Mechanisms of interleukin 4 mediated increase in efficacy of vaccines against opioid use disorders. NPJ Vaccines. 2020;5:99 pubmed publisher
Pan Z, Zhou Z, Zhang H, Zhao H, Song P, Wang D, et al. CD90 serves as differential modulator of subcutaneous and visceral adipose-derived stem cells by regulating AKT activation that influences adipose tissue and metabolic homeostasis. Stem Cell Res Ther. 2019;10:355 pubmed publisher
Melo Gonzalez F, Kammoun H, Evren E, Dutton E, Papadopoulou M, Bradford B, et al. Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria. J Exp Med. 2019;216:728-742 pubmed publisher
Schrock D, Leddon S, Hughson A, Miller J, Lacy Hulbert A, Fowell D. Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Madaro L, Passafaro M, Sala D, Etxaniz U, Lugarini F, Proietti D, et al. Denervation-activated STAT3-IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis. Nat Cell Biol. 2018;20:917-927 pubmed publisher
Urata S, Kenyon E, Nayak D, Cubitt B, Kurosaki Y, Yasuda J, et al. BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection. PLoS Pathog. 2018;14:e1007172 pubmed publisher
Shabaneh T, Molodtsov A, Steinberg S, Zhang P, Torres G, Mohamed G, et al. Oncogenic BRAFV600E Governs Regulatory T-cell Recruitment during Melanoma Tumorigenesis. Cancer Res. 2018;78:5038-5049 pubmed publisher
Sparber F, Dolowschiak T, Mertens S, Lauener L, Clausen B, Joller N, et al. Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection. PLoS Pathog. 2018;14:e1007069 pubmed publisher
Owen D, Mahmud S, Vang K, Kelly R, Blazar B, Smith K, et al. Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis. J Immunol. 2018;200:3926-3933 pubmed publisher
An Z, Sabalić M, Bloomquist R, Fowler T, Streelman T, Sharpe P. A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors. Nat Commun. 2018;9:378 pubmed publisher
Ibitokou S, Dillon B, Sinha M, Szczesny B, Delgadillo A, Reda Abdelrahman D, et al. Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection. J Immunol. 2018;200:643-656 pubmed publisher
Sharma D, Malik A, Guy C, Karki R, Vogel P, Kanneganti T. Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis. Gastroenterology. 2018;154:948-964.e8 pubmed publisher
Hondowicz B, Kim K, Ruterbusch M, Keitany G, Pepper M. IL-2 is required for the generation of viral-specific CD4+ Th1 tissue-resident memory cells and B cells are essential for maintenance in the lung. Eur J Immunol. 2017;: pubmed publisher
Ames R, Ting L, Gendlina I, Kim K, Macian F. The Transcription Factor NFAT1 Participates in the Induction of CD4+ T Cell Functional Exhaustion during Plasmodium yoelii Infection. Infect Immun. 2017;85: pubmed publisher
Bishop N, Nelsen M, Beard K, Coulombe M, Gill R. Differential Impact of Chronic Hyperglycemia on Humoral Versus Cellular Primary Alloimmunity. Diabetes. 2017;66:981-986 pubmed publisher
Wilson G, Hewit K, Pallas K, Cairney C, Lee K, Hansell C, et al. Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland. Development. 2017;144:74-82 pubmed publisher
Massoud A, Charbonnier L, Lopez D, Pellegrini M, Phipatanakul W, Chatila T. An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells. Nat Med. 2016;22:1013-22 pubmed publisher
Prieto J, León M, Ponsoda X, Sendra R, Bort R, Ferrer Lorente R, et al. Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming. Nat Commun. 2016;7:11124 pubmed publisher
Hoffmann M, Molina Mendiola C, Nelson A, Parks C, Reyes E, Hansen M, et al. Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo. Sci Adv. 2015;1:e1500415 pubmed publisher
Ji J, Griffiths K, Milburn P, Hirst T, O Neill H. The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cells. J Cell Mol Med. 2015;19:2019-31 pubmed publisher
Bradfute S, Anthony S, Stuthman K, Ayithan N, Tailor P, Shaia C, et al. Mechanisms of immunity in post-exposure vaccination against Ebola virus infection. PLoS ONE. 2015;10:e0118434 pubmed publisher
Tran K, Jackson S, Olufs Z, Zaidan N, Leng N, Kendziorski C, et al. Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways. Nat Commun. 2015;6:6188 pubmed publisher
Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, et al. Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses. elife. 2014;3:e04177 pubmed publisher
Saunders A, Shim Y, Johnson P. Innate immune cell CD45 regulates lymphopenia-induced T cell proliferation. J Immunol. 2014;193:2831-42 pubmed publisher
Mahmud S, Manlove L, Schmitz H, Xing Y, Wang Y, Owen D, et al. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat Immunol. 2014;15:473-81 pubmed publisher
Osada M, Singh V, Wu K, Sant Angelo D, Pezzano M. Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus. PLoS ONE. 2013;8:e83024 pubmed publisher
Zhong M, Veillette A. Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity. Mol Cell Biol. 2013;33:1223-32 pubmed publisher
Periasamy P, Tan J, O Neill H. Novel splenic antigen-presenting cells derive from a Lin(-) c-kit(lo) progenitor. J Leukoc Biol. 2013;93:63-9 pubmed publisher
Johnson L, Jameson S. TGF-? sensitivity restrains CD8+ T cell homeostatic proliferation by enforcing sensitivity to IL-7 and IL-15. PLoS ONE. 2012;7:e42268 pubmed publisher
Do J, Valujskikh A, Vignali D, Fairchild R, Min B. Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A. 2012;109:12698-703 pubmed publisher
Newrzela S, Al Ghaili N, Heinrich T, Petkova M, Hartmann S, Rengstl B, et al. T-cell receptor diversity prevents T-cell lymphoma development. Leukemia. 2012;26:2499-507 pubmed publisher
Tan J, O Neill H. Myelopoiesis in spleen-producing distinct dendritic-like cells. J Cell Mol Med. 2012;16:1924-33 pubmed publisher
Kreisel D, Sugimoto S, Zhu J, Nava R, Li W, Okazaki M, et al. Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance. Blood. 2011;118:6172-82 pubmed publisher
Svobodova E, Krulova M, Zajicova A, Pokorna K, Prochazkova J, Trosan P, et al. The role of mouse mesenchymal stem cells in differentiation of naive T-cells into anti-inflammatory regulatory T-cell or proinflammatory helper T-cell 17 population. Stem Cells Dev. 2012;21:901-10 pubmed publisher
Sato Hashimoto M, Saito Y, Ohnishi H, Iwamura H, Kanazawa Y, Kaneko T, et al. Signal regulatory protein ? regulates the homeostasis of T lymphocytes in the spleen. J Immunol. 2011;187:291-7 pubmed publisher
Bolduc A, Long E, Stapler D, Cascalho M, Tsubata T, Koni P, et al. Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas. J Immunol. 2010;185:220-30 pubmed publisher
Tan J, Quah B, Griffiths K, Periasamy P, Hey Y, O Neill H. Identification of a novel antigen cross-presenting cell type in spleen. J Cell Mol Med. 2011;15:1189-99 pubmed publisher
Gelman A, Okazaki M, Sugimoto S, Li W, Kornfeld C, Lai J, et al. CCR2 regulates monocyte recruitment as well as CD4 T1 allorecognition after lung transplantation. Am J Transplant. 2010;10:1189-99 pubmed publisher
Tan J, Periasamy P, O Neill H. Delineation of precursors in murine spleen that develop in contact with splenic endothelium to give novel dendritic-like cells. Blood. 2010;115:3678-85 pubmed publisher
Tan J, O Neill H. Haematopoietic stem cells in spleen have distinct differentiative potential for antigen presenting cells. J Cell Mol Med. 2010;14:2144-50 pubmed publisher
Periasamy P, Tan J, Griffiths K, O Neill H. Splenic stromal niches support hematopoiesis of dendritic-like cells from precursors in bone marrow and spleen. Exp Hematol. 2009;37:1060-71 pubmed publisher
Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed publisher
Kapp J, Honjo K, Kapp L, Goldsmith K, Bucy R. Antigen, in the presence of TGF-beta, induces up-regulation of FoxP3gfp+ in CD4+ TCR transgenic T cells that mediate linked suppression of CD8+ T cell responses. J Immunol. 2007;179:2105-14 pubmed
Besseyrias V, Fiorini E, Strobl L, Zimber Strobl U, Dumortier A, Koch U, et al. Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med. 2007;204:331-43 pubmed
Lohr J, Knoechel B, Wang J, Villarino A, Abbas A. Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med. 2006;203:2785-91 pubmed
Pennello A, Taylor J, Matlack R, Karp J, Riggs J. Spiny mice (Acomys cahirinus) do not respond to thymus-independent type 2 antigens. Dev Comp Immunol. 2006;30:1181-90 pubmed
Nishikomori R, Ehrhardt R, Strober W. T helper type 2 cell differentiation occurs in the presence of interleukin 12 receptor beta2 chain expression and signaling. J Exp Med. 2000;191:847-58 pubmed
Sugai M, Kondo S, Shimizu A, Honjo T. Isolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase. Nucleic Acids Res. 1998;26:911-8 pubmed
Ledbetter J, Herzenberg L. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol Rev. 1979;47:63-90 pubmed
product information
Product Type :
Antibody
Product Name :
CD90.2 (Thy-1.2) Monoclonal Antibody (30-H12), eBioscience
Catalog # :
14-0903-85
Quantity :
500 µg
Price :
US 197.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent
Species :
Mouse
Clone :
30-H12
Isotype :
IgG2b, kappa
Storage :
4° C
Description :
CD90.2 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90.2 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. Thy 1 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90.2 is an 18 kDa plasma membrane antigen expressed by hematopoietic cells and neurons in all species studied, highly expressed in connective tissue, various fibroblast and stromal cell lines and lastly, by tumor endothelial cell lines. In the mouse, CD90.2 is expressed on all thymocytes and peripheral T lymphocytes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent
Aliases :
CD90; FLJ33325; T25; Thy 1.2; Thy1; Thy-1; Thy-1 antigen; thy-1 membrane glycoprotein; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA