This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD83 Monoclonal Antibody (HB15e), eBioscience
catalog :
14-0839-95
quantity :
10 mg
price :
US 3685.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HB15e

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 14
Reference
Li M, Luo L, Lin C, Ni B, Zou L, Song Z, et al. Vitamin D3 mitigates autoimmune inflammation caused by activation of myeloid dendritic cells in SLE. Exp Dermatol. 2024;33:e14926 pubmed publisher
Lin W, Chang Y, Hong M, Hsu T, Lee K, Lin C, et al. STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT-MET switch and cancer metastasis. Oncogene. 2021;40:791-805 pubmed publisher
Grosche L, Muhl Zurbes P, Ciblis B, Krawczyk A, Kuhnt C, Kamm L, et al. Herpes Simplex Virus Type-2 Paralyzes the Function of Monocyte-Derived Dendritic Cells. Viruses. 2020;12: pubmed publisher
Tong D, Zhang L, Ning F, Xu Y, Hu X, Shi Y. Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival. Protein Cell. 2020;11:108-123 pubmed publisher
El Ashmawy N, El Zamarany E, Salem M, El Bahrawy H, Al Ashmawy G. In vitro and in vivo studies of the immunomodulatory effect of Echinacea purpurea on dendritic cells. J Genet Eng Biotechnol. 2015;13:185-192 pubmed publisher
Carlsson J, Wold A, Sandberg A, Östman S. The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. PLoS ONE. 2015;10:e0143741 pubmed publisher
Harfuddin Z, Kwajah S, Chong Nyi Sim A, MacAry P, Schwarz H. CD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses. Oncoimmunology. 2013;2:e26859 pubmed
Watchmaker P, Lahl K, Lee M, Baumjohann D, Morton J, Kim S, et al. Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice. Nat Immunol. 2014;15:98-108 pubmed publisher
den Hartog G, van Altena C, Savelkoul H, van Neerven R. The mucosal factors retinoic acid and TGF-?1 induce phenotypically and functionally distinct dendritic cell types. Int Arch Allergy Immunol. 2013;162:225-36 pubmed publisher
Côté S, Plante A, Tardif M, Tremblay M. Dectin-1/TLR2 and NOD2 agonists render dendritic cells susceptible to infection by X4-using HIV-1 and promote cis-infection of CD4(+) T cells. PLoS ONE. 2013;8:e67735 pubmed publisher
Miles B, Scisci E, CARRION J, Sabino G, Genco C, Cutler C. Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen. J Leukoc Biol. 2013;94:281-9 pubmed publisher
Kwajah M M S, Schwarz H. CD137 ligand signaling induces human monocyte to dendritic cell differentiation. Eur J Immunol. 2010;40:1938-49 pubmed publisher
Freeman C, Martinez F, Han M, Ames T, Chensue S, Todt J, et al. Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009;180:1179-88 pubmed publisher
Huntington N, Legrand N, Alves N, Jaron B, Weijer K, Plet A, et al. IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med. 2009;206:25-34 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD83 Monoclonal Antibody (HB15e), eBioscience
Catalog # :
14-0839-95
Quantity :
10 mg
Price :
US 3685.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1 ug/test
Species :
Human
Clone :
HB15e
Isotype :
IgG1, kappa
Storage :
4 C
Description :
CD83 cell surface antigen is a 40-45kD glycoprotein expressed by peripheral blood dendritic cells. Peripheral lymphocytes can be induced to express very low levels of CD83 after culture in agents such as Con A or PHA. In immunohistology, CD83 is shown to be expressed strongly by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centres. CD83 is also expressed by Langerhan's cells in the skin. The CD83 antigen is a 186-amino-acid single-chain glycoprotein and this molecule is a member of the immunoglobulin superfamily that is composed of an extracellular V-type Ig-like single domain, a transmembrane region, and a short, 40-amino-acid cytoplasmic tail. CD83 antigen undergoes extensive post-translational glycosylation, since the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immuno-phenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also co-express T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36), cytokine receptors as well as other cell surface molecules. Diseases associated with CD83 dysfunction include plague and Rift Valley Fever.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/test
Aliases :
B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA