CD83 Monoclonal Antibody (HB15e), eBioscience™ | Invitrogen 14-0839-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD83 Monoclonal Antibody (HB15e), eBioscience™

catalog :

14-0839-80

quantity :

25µg

price :

US 84.75

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HB15e

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 44

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s2b	Harfuddin Z, Dharmadhikari B, Wong S, Duan K, Poidinger M, Kwajah S, et al. Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype. Sci Rep. 2016;6:29712 pubmed publisher
flow cytometry; human	Royle C, Graham D, Sharma S, Fuchs D, Boasso A. HIV-1 and HIV-2 differentially mature plasmacytoid dendritic cells into IFN-producing cells or APCs. J Immunol. 2014;193:3538-48 pubmed publisher
flow cytometry; human; fig 5	Schrauf C, Kirchberger S, Majdic O, Seyerl M, Zlabinger G, Stuhlmeier K, et al. The ssRNA genome of human rhinovirus induces a type I IFN response but fails to induce maturation in human monocyte-derived dendritic cells. J Immunol. 2009;183:4440-8 pubmed publisher
flow cytometry; human	Huntington N, Legrand N, Alves N, Jaron B, Weijer K, Plet A, et al. IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med. 2009;206:25-34 pubmed publisher
	Carlsson J, Wold A, Sandberg A, Ã–stman S. The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. PLoS ONE. 2015;10:e0143741 pubmed publisher
	Lopes D, Fernandes J, Cardoso T, Bafica A, Oliveira S, Carvalho E, et al. Dendritic cell profile induced by Schistosoma mansoni antigen in cutaneous leishmaniasis patients. Biomed Res Int. 2014;2014:743069 pubmed publisher
	Harfuddin Z, Kwajah S, Chong Nyi Sim A, MacAry P, Schwarz H. CD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses. Oncoimmunology. 2013;2:e26859 pubmed
	Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H. CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells. Br J Haematol. 2014;165:134-44 pubmed publisher
	Watchmaker P, Lahl K, Lee M, Baumjohann D, Morton J, Kim S, et al. Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice. Nat Immunol. 2014;15:98-108 pubmed publisher
	Côté S, Plante A, Tardif M, Tremblay M. Dectin-1/TLR2 and NOD2 agonists render dendritic cells susceptible to infection by X4-using HIV-1 and promote cis-infection of CD4(+) T cells. PLoS ONE. 2013;8:e67735 pubmed publisher
	Miles B, Scisci E, CARRION J, Sabino G, Genco C, Cutler C. Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen. J Leukoc Biol. 2013;94:281-9 pubmed publisher
	Zhai R, Jiang A, Wang H, Ma L, Ren X, Jiang J, et al. Histamine enhances HIV-1-induced modulation of dendritic cells to skew naïve T cell differentiation toward regulatory T cells. Virology. 2013;442:163-72 pubmed publisher
	Méndez Reguera A, Pérez Montesinos G, Alcántara Hernández M, Martínez Estrada V, Cazarin Barrientos J, Rojas Espinosa O, et al. Pathogenic CCR6+ dendritic cells in the skin lesions of discoid lupus patients: a role for damage-associated molecular patterns. Eur J Dermatol. 2013;23:169-82 pubmed publisher
	Yan R, Zhong W, Zhu Y, Zhang X. Trichosanthin-stimulated dendritic cells induce a type 2 helper T lymphocyte response through the OX40 ligand. J Investig Allergol Clin Immunol. 2012;22:491-500 pubmed
	Hostmann A, Kapp K, Beutner M, Ritz J, Loddenkemper C, Ignatius R, et al. Dendritic cells from human mesenteric lymph nodes in inflammatory and non-inflammatory bowel diseases: subsets and function of plasmacytoid dendritic cells. Immunology. 2013;139:100-8 pubmed publisher
	Frick S, Bacher N, Baier G, Mailänder V, Landfester K, Steinbrink K. Functionalized polystyrene nanoparticles trigger human dendritic cell maturation resulting in enhanced CD4+ T cell activation. Macromol Biosci. 2012;12:1637-47 pubmed publisher
	Shen C, Jia Y, Tian R, Ding M, Zhang C, Wang J. Translation of Pur-? is targeted by cellular miRNAs to modulate the differentiation-dependent susceptibility of monocytes to HIV-1 infection. FASEB J. 2012;26:4755-64 pubmed publisher
	Qin Y, Li Y, Jiang A, Jiang J, Wang J. Stimulation of Cryptococcus neoformans isolated from skin lesion of AIDS patient matures dendritic cells and promotes HIV-1 trans-infection. Biochem Biophys Res Commun. 2012;423:709-14 pubmed publisher
	Silk K, Leishman A, Nishimoto K, Reddy A, Fairchild P. Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype. J Biomed Biotechnol. 2012;2012:172420 pubmed publisher
	Qin Y, Li Y, Liu W, Tian R, Guo Q, Li S, et al. Penicillium marneffei-stimulated dendritic cells enhance HIV-1 trans-infection and promote viral infection by activating primary CD4+ T cells. PLoS ONE. 2011;6:e27609 pubmed publisher
	Presicce P, Shaw J, Miller C, Shacklett B, Chougnet C. Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells. AIDS. 2012;26:263-73 pubmed publisher
	Heydenreich B, Bellinghausen I, Konig B, Becker W, Grabbe S, Petersen A, et al. Gram-positive bacteria on grass pollen exhibit adjuvant activity inducing inflammatory T cell responses. Clin Exp Allergy. 2012;42:76-84 pubmed publisher
	Silk K, Silk J, Ichiryu N, Davies T, Nolan K, Leishman A, et al. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells. Gene Ther. 2012;19:1035-40 pubmed publisher
	Chen L, Gao C, Zhu Y, Zhong W, Hu Y, Zhang X. Two novel monoclonal antibodies produced against human CD83 molecule. Hybridoma (Larchmt). 2011;30:297-302 pubmed publisher
	Uldrick T, Polizzotto M, Aleman K, O Mahony D, Wyvill K, Wang V, et al. High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy. Blood. 2011;117:6977-86 pubmed publisher
	Diou J, Tardif M, Barat C, Tremblay M. Dendritic cells derived from hemozoin-loaded monocytes display a partial maturation phenotype that promotes HIV-1 trans-infection of CD4+ T cells and virus replication. J Immunol. 2010;184:2899-907 pubmed publisher
	Holmstrøm K, Pedersen A, Claesson M, Zocca M, Jensen S. Identification of a microRNA signature in dendritic cell vaccines for cancer immunotherapy. Hum Immunol. 2010;71:67-73 pubmed publisher
	Kvistborg P, Boegh M, Pedersen A, Claesson M, Zocca M. Fast generation of dendritic cells. Cell Immunol. 2009;260:56-62 pubmed publisher
	Freeman C, Martinez F, Han M, Ames T, Chensue S, Todt J, et al. Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009;180:1179-88 pubmed publisher
	Pedersen A, Holmstrøm K, Jensen S, Fuchs D, Rasmussen S, Kvistborg P, et al. Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells. Clin Exp Immunol. 2009;157:48-59 pubmed publisher
	van Velzen M, Laman J, Kleinjan A, Poot A, Osterhaus A, Verjans G. Neuron-interacting satellite glial cells in human trigeminal ganglia have an APC phenotype. J Immunol. 2009;183:2456-61 pubmed publisher
	Svensson M. Isolation and culture of human hematopoietic progenitors for studies of dendritic cell biology. Methods Mol Biol. 2009;531:187-202 pubmed publisher
	Gulen D, Abe F, Maas S, Reed E, Cowan K, Pirruccello S, et al. Closing the manufacturing process of dendritic cell vaccines transduced with adenovirus vectors. Int Immunopharmacol. 2008;8:1728-36 pubmed publisher
	Velásquez Lopera M, Correa L, Garcia L. Human spleen contains different subsets of dendritic cells and regulatory T lymphocytes. Clin Exp Immunol. 2008;154:107-14 pubmed publisher
	Holden N, Bedford P, McCarthy N, Marks N, Ind P, Jowsey I, et al. Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity. Clin Exp Allergy. 2008;38:1148-59 pubmed publisher
	Reske A, Pollara G, Krummenacher C, Katz D, Chain B. Glycoprotein-dependent and TLR2-independent innate immune recognition of herpes simplex virus-1 by dendritic cells. J Immunol. 2008;180:7525-36 pubmed
	Metharom P, Velten F, Goerdt S. Highly phagocytic, CD4hi, CD14hi and CD16hi antigen-presenting cells modulated by tumour-conditioned media retain the capacity to mature and induce TH1 T-cell proliferation. Mol Immunol. 2006;43:2070-82 pubmed
	Amanuma R, Nakajima T, Yoshie H, Yamazaki K. Increased infiltration of CD1d and natural killer T cells in periodontal disease tissues. J Periodontal Res. 2006;41:73-9 pubmed
	Roura Mir C, Wang L, Cheng T, Matsunaga I, Dascher C, Peng S, et al. Mycobacterium tuberculosis regulates CD1 antigen presentation pathways through TLR-2. J Immunol. 2005;175:1758-66 pubmed
	Ashton Chess J, Blancho G. An in vitro evaluation of the potential suitability of peripheral blood CD14(+) and bone marrow CD34(+)-derived dendritic cells for a tolerance inducing regimen in the primate. J Immunol Methods. 2005;297:237-52 pubmed
	McCully M, Chau T, Luke P, Blake P, Madrenas J. Characterization of human peritoneal dendritic cell precursors and their involvement in peritonitis. Clin Exp Immunol. 2005;139:513-25 pubmed
	Zhou L, Tedder T. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci U S A. 1996;93:2588-92 pubmed
	Zhou L, Tedder T. Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J Immunol. 1995;154:3821-35 pubmed
	Zhou L, Tedder T. A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells. Blood. 1995;86:3295-301 pubmed

product information

Product Type :

Antibody

Product Name :

CD83 Monoclonal Antibody (HB15e), eBioscience™

Catalog # :

14-0839-80

Quantity :

25µg

Price :

US 84.75

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 µg/test

Species :

Human

Clone :

HB15e

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD83 cell surface antigen is a 40-45kD glycoprotein expressed by peripheral blood dendritic cells. Peripheral lymphocytes can be induced to express very low levels of CD83 after culture in agents such as Con A or PHA. In immunohistology, CD83 is shown to be expressed strongly by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centres. CD83 is also expressed by Langerhan's cells in the skin. The CD83 antigen is a 186-amino-acid single-chain glycoprotein and this molecule is a member of the immunoglobulin superfamily that is composed of an extracellular V-type Ig-like single domain, a transmembrane region, and a short, 40-amino-acid cytoplasmic tail. CD83 antigen undergoes extensive post-translational glycosylation, since the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immuno-phenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also co-express T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36), cytokine receptors as well as other cell surface molecules. Diseases associated with CD83 dysfunction include plague and Rift Valley Fever.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; Cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83

more info or order :

Invitrogen product webpage