CD83 Monoclonal Antibody (Michel-17 (Michel17)), eBioscience™ | Invitrogen 14-0831-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD83 Monoclonal Antibody (Michel-17 (Michel17)), eBioscience™

catalog :

14-0831-82

quantity :

100µg

price :

US 214

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Michel-17 (Michel17)

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 33

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig s2b	Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed publisher
flow cytometry; mouse; fig 4	Ellestad K, Tsutsui S, Noorbakhsh F, Warren K, Yong V, Pittman Q, et al. Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells. J Immunol. 2009;183:298-309 pubmed publisher
flow cytometry; mouse	Reinwald S, Wiethe C, Westendorf A, Breloer M, Probst Kepper M, Fleischer B, et al. CD83 expression in CD4+ T cells modulates inflammation and autoimmunity. J Immunol. 2008;180:5890-7 pubmed
	Wang H, Lin J, Zeng L, Ouyang C, Ran P, Yang P, et al. Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells. Sci Rep. 2017;7:8519 pubmed publisher
	Wang H, Mo L, Xiao X, An S, Liu X, Ba J, et al. Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model. Sci Rep. 2017;7:43322 pubmed publisher
	Wang H, Hu W, Liang Z, Zeng L, Li J, Yan H, et al. Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells. Am J Transl Res. 2016;8:5320-5329 pubmed
	Carlsson J, Wold A, Sandberg A, Ã–stman S. The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. PLoS ONE. 2015;10:e0143741 pubmed publisher
	Wanderley J, Thorpe P, Barcinski M, Soong L. Phosphatidylserine exposure on the surface of Leishmania amazonensis amastigotes modulates in vivo infection and dendritic cell function. Parasite Immunol. 2013;35:109-119 pubmed publisher
	Dinh T, Kyaw T, Kanellakis P, To K, Tipping P, Toh B, et al. Cytokine therapy with interleukin-2/anti-interleukin-2 monoclonal antibody complexes expands CD4+CD25+Foxp3+ regulatory T cells and attenuates development and progression of atherosclerosis. Circulation. 2012;126:1256-66 pubmed publisher
	Kyaw T, Tay C, Hosseini H, Kanellakis P, Gadowski T, Mackay F, et al. Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation. PLoS ONE. 2012;7:e29371 pubmed publisher
	Cao S, Li Y, Ye J, Yang X, Chen L, Liu X, et al. Japanese encephalitis Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion of regulatory T cells. Virol J. 2011;8:39 pubmed publisher
	Tze L, Horikawa K, Domaschenz H, Howard D, Roots C, Rigby R, et al. CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. J Exp Med. 2011;208:149-65 pubmed publisher
	Li Y, Ye J, Yang X, Xu M, Chen L, Mei L, et al. Infection of mouse bone marrow-derived dendritic cells by live attenuated Japanese encephalitis virus induces cells maturation and triggers T cells activation. Vaccine. 2011;29:855-62 pubmed publisher
	Kanellakis P, Agrotis A, Kyaw T, Koulis C, Ahrens I, Mori S, et al. High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein e-deficient mice. Arterioscler Thromb Vasc Biol. 2011;31:313-9 pubmed publisher
	Vallerskog T, Martens G, Kornfeld H. Diabetic mice display a delayed adaptive immune response to Mycobacterium tuberculosis. J Immunol. 2010;184:6275-82 pubmed publisher
	Ingersoll M, Spanbroek R, Lottaz C, Gautier E, Frankenberger M, Hoffmann R, et al. Comparison of gene expression profiles between human and mouse monocyte subsets. Blood. 2010;115:e10-9 pubmed publisher
	Perruche S, Zhang P, Maruyama T, Bluestone J, Saas P, Chen W. Lethal effect of CD3-specific antibody in mice deficient in TGF-beta1 by uncontrolled flu-like syndrome. J Immunol. 2009;183:953-61 pubmed publisher
	Lin Y, Wang W, Jin H, Zhong Y, Di J, Zeng S, et al. Comparison of murine thymic stromal lymphopoietin- and polyinosinic polycytidylic acid-mediated placental dendritic cell activation. J Reprod Immunol. 2009;79:119-28 pubmed publisher
	Kawasaki T, Choudhry M, Schwacha M, Bland K, Chaudry I. Effect of interleukin-15 on depressed splenic dendritic cell functions following trauma-hemorrhage. Am J Physiol Cell Physiol. 2009;296:C124-30 pubmed publisher
	Hussain S, He P, Subleski J, Hofseth L, Trivers G, Mechanic L, et al. Nitric oxide is a key component in inflammation-accelerated tumorigenesis. Cancer Res. 2008;68:7130-6 pubmed publisher
	Lechmann M, Shuman N, Wakeham A, Mak T. The CD83 reporter mouse elucidates the activity of the CD83 promoter in B, T, and dendritic cell populations in vivo. Proc Natl Acad Sci U S A. 2008;105:11887-92 pubmed publisher
	Behrends J, Karsten C, Wilke S, Röbke A, Kruse A. Identification of ITGA4/ITGB7 and ITGAE/ITGB7 expressing subsets of decidual dendritic-like cells within distinct microdomains of the pregnant mouse uterus. Biol Reprod. 2008;79:624-32 pubmed publisher
	Xin L, Li K, Soong L. Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes. Mol Immunol. 2008;45:3371-82 pubmed publisher
	Vasquez R, Xin L, Soong L. Effects of CXCL10 on dendritic cell and CD4+ T-cell functions during Leishmania amazonensis infection. Infect Immun. 2008;76:161-9 pubmed
	Nabekura T, Nagasawa T, Nakauchi H, Onodera M. An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2. Cancer Immunol Immunother. 2008;57:611-22 pubmed
	Kawasaki T, Choudhry M, Suzuki T, Schwacha M, Bland K, Chaudry I. 17beta-Estradiol's salutary effects on splenic dendritic cell functions following trauma-hemorrhage are mediated via estrogen receptor-alpha. Mol Immunol. 2008;45:376-85 pubmed
	Suzuki T, Shimizu T, Yu H, Hsieh Y, Choudhry M, Bland K, et al. Estrogen receptor-alpha predominantly mediates the salutary effects of 17beta-estradiol on splenic macrophages following trauma-hemorrhage. Am J Physiol Cell Physiol. 2007;293:C978-84 pubmed
	Ma X, Tian D, Xu D, Yang D, Zhu H, Liang Z, et al. Uric acid enhances T cell immune responses to hepatitis B surface antigen-pulsed-dendritic cells in mice. World J Gastroenterol. 2007;13:1060-6 pubmed
	Kawasaki T, Fujimi S, Lederer J, Hubbard W, Choudhry M, Schwacha M, et al. Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice. J Immunol. 2006;177:4514-20 pubmed
	Warncke M, Dodero A, Dierbach H, Follo M, Veelken H. Murine dendritic cells generated under serum-free conditions have a mature phenotype and efficiently induce primary immune responses. J Immunol Methods. 2006;310:1-11 pubmed
	Wolenski M, Cramer S, Ehrlich S, Steeg C, Fleischer B, von Bonin A. Enhanced activation of CD83-positive T cells. Scand J Immunol. 2003;58:306-11 pubmed
	Wolenski M, Cramer S, Ehrlich S, Steeg C, Grossschupff G, Tenner Racz K, et al. Expression of CD83 in the murine immune system. Med Microbiol Immunol. 2003;192:189-92 pubmed
	Cramer S, Trumpfheller C, Mehlhoop U, More S, Fleischer B, von Bonin A. Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells. Int Immunol. 2000;12:1347-51 pubmed

product information

Product Type :

Antibody

Product Name :

CD83 Monoclonal Antibody (Michel-17 (Michel17)), eBioscience™

Catalog # :

14-0831-82

Quantity :

100µg

Price :

US 214

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test

Species :

Mouse

Clone :

Michel-17 (Michel17)

Isotype :

IgG1

Storage :

4° C

Description :

CD83 cell surface antigen is a 40-45kD glycoprotein expressed by peripheral blood dendritic cells. Peripheral lymphocytes can be induced to express very low levels of CD83 after culture in agents such as Con A or PHA. In immunohistology, CD83 is shown to be expressed strongly by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centres. CD83 is also expressed by Langerhan's cells in the skin. The CD83 antigen is a 186-amino-acid single-chain glycoprotein and this molecule is a member of the immunoglobulin superfamily that is composed of an extracellular V-type Ig-like single domain, a transmembrane region, and a short, 40-amino-acid cytoplasmic tail. CD83 antigen undergoes extensive post-translational glycosylation, since the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immuno-phenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also co-express T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36), cytokine receptors as well as other cell surface molecules. Diseases associated with CD83 dysfunction include plague and Rift Valley Fever.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test

Aliases :

B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; Cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83

more info or order :

Invitrogen product webpage