CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), eBioscience™ | Invitrogen 14-0731-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), eBioscience™

catalog :

14-0731-82

quantity :

100µg

price :

US 107

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBioTY/11.8 (TY/11.8)

reactivity :

mouse

application :

immunohistochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...	ElTanbouly M, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, et al. VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance. Science. 2020;367: pubmed publisher
flow cytometry; mouse; loading ...; fig 4a	Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018;215:249-262 pubmed publisher
flow cytometry; mouse; fig s2	Cañete A, Carmona R, Ariza L, Sanchez M, Rojas A, Muñoz Chápuli R. A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice. Haematologica. 2017;102:647-655 pubmed publisher
flow cytometry; mouse; loading ...; fig 2c	Butcher M, Filipowicz A, Waseem T, McGary C, Crow K, Magilnick N, et al. Atherosclerosis-Driven Treg Plasticity Results in Formation of a Dysfunctional Subset of Plastic IFN?+ Th1/Tregs. Circ Res. 2016;119:1190-1203 pubmed publisher
flow cytometry; mouse; fig 4d	Gossmann J, Stolte M, Lohoff M, Yu P, Moll R, Finkernagel F, et al. A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma. PLoS ONE. 2016;11:e0150411 pubmed publisher
flow cytometry; mouse	Yuan X, Dee M, Altman N, Malek T. IL-2RÎ²-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa. J Immunol. 2015;194:1334-46 pubmed publisher
immunohistochemistry; mouse; 1:1,000-1,500	PFISTER S, Weber T, HÃ¤rtig W, Schwerdel C, Elsaesser R, Knuesel I, et al. Novel role of cystic fibrosis transmembrane conductance regulator in maintaining adult mouse olfactory neuronal homeostasis. J Comp Neurol. 2015;523:406-30 pubmed publisher
	Greenwald A, Licht T, Kumar S, Oladipupo S, Iyer S, Grunewald M, et al. VEGF expands erythropoiesis via hypoxia-independent induction of erythropoietin in noncanonical perivascular stromal cells. J Exp Med. 2019;216:215-230 pubmed publisher
	Guichard V, Bonilla N, Durand A, Audemard Verger A, Guilbert T, Martin B, et al. Calcium-mediated shaping of naive CD4 T-cell phenotype and function. elife. 2017;6: pubmed publisher
	Buus T, Ødum N, Geisler C, Lauritsen J. Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus. Nat Commun. 2017;8:1911 pubmed publisher
	Chamieh F, Collignon A, Coyac B, Lesieur J, Ribes S, Sadoine J, et al. Accelerated craniofacial bone regeneration through dense collagen gel scaffolds seeded with dental pulp stem cells. Sci Rep. 2016;6:38814 pubmed publisher
	Bemark M, Hazanov H, Strömberg A, Komban R, Holmqvist J, Köster S, et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat Commun. 2016;7:12698 pubmed publisher
	Cheng C, Lee Y, Lin S, HuangFu W, Liu I. Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells. J Biomed Sci. 2014;21:21 pubmed publisher
	Du Y, Roh D, Mann M, Funderburgh M, Funderburgh J, Schuman J. Multipotent stem cells from trabecular meshwork become phagocytic TM cells. Invest Ophthalmol Vis Sci. 2012;53:1566-75 pubmed publisher
	Yan A, Avraham T, Zampell J, Haviv Y, Weitman E, Mehrara B. Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-?1 inhibition. Future Oncol. 2011;7:1457-73 pubmed publisher
	Hawiger D, Wan Y, Eynon E, Flavell R. The transcription cofactor Hopx is required for regulatory T cell function in dendritic cell-mediated peripheral T cell unresponsiveness. Nat Immunol. 2010;11:962-8 pubmed publisher
	Kobie J, Shah P, Yang L, Rebhahn J, Fowell D, Mosmann T. T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. J Immunol. 2006;177:6780-6 pubmed
	Yang L, Kobie J, Mosmann T. CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells. J Immunol. 2005;175:6458-64 pubmed
	Eliopoulos N, Stagg J, Lejeune L, Pommey S, Galipeau J. Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood. 2005;106:4057-65 pubmed
	Yamashita Y, Hooker S, Jiang H, Laurent A, Resta R, Khare K, et al. CD73 expression and fyn-dependent signaling on murine lymphocytes. Eur J Immunol. 1998;28:2981-90 pubmed

product information

Product Type :

Antibody

Product Name :

CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), eBioscience™

Catalog # :

14-0731-82

Quantity :

100µg

Price :

US 107

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.06 µg/test, Immunohistochemistry: Assay-Dependent

Species :

Mouse

Clone :

eBioTY/11.8 (TY/11.8)

Isotype :

IgG1

Storage :

4° C

Description :

CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations. Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis. Two transcript variants encoding different isoforms of CD73 have been found.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.06 µg/test, Immunohistochemistry: Assay-Dependent

Aliases :

2210401F01Rik; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; Ecto-5'-nucleotidase; eN; eNT; NT; Nt5; NT5E; Nte; Purine 5-Prime-Nucleotidase

more info or order :

Invitrogen product webpage