product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), eBioscience™
catalog :
14-0719-80
quantity :
25µg
price :
US 127
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OKT9 (OKT-9)
reactivity :
human, dogs
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
Invitrogen product webpage
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s11d
Canver M, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern E, et al. Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci. Nat Genet. 2017;49:625-634 pubmed publisher
  • flow cytometry; human; loading ...; fig 9h
Goodier M, Rodríguez Galán A, Lusa C, Nielsen C, Darboe A, Moldoveanu A, et al. Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection. J Immunol. 2016;197:313-25 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a, s1b, s1c
Notta F, Zandi S, Takayama N, Dobson S, Gan O, Wilson G, et al. Distinct routes of lineage development reshape the human blood hierarchy across ontogeny. Science. 2016;351:aab2116 pubmed publisher
  • flow cytometry; human; fig 1e
Jobin C, Cloutier M, Simard C, Néron S. Heterogeneity of in vitro-cultured CD34+ cells isolated from peripheral blood. Cytotherapy. 2015;17:1472-84 pubmed publisher
  • western blot; human
Fromm J, Tagliente D, Shaver A, Neppalli V, Craig F. Case study interpretation: Report from the ICCS Annual Meeting, Seattle, 2014. Cytometry B Clin Cytom. 2015;88:413-24 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Hänggi P, Telezhkin V, Kemp P, Schmugge M, Gassmann M, Goede J, et al. Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells. Am J Physiol Cell Physiol. 2015;308:C993-C1007 pubmed publisher
  • flow cytometry; human
Badarau A, Rouha H, Malafa S, Logan D, HÃ¥kansson M, Stulik L, et al. Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH. J Biol Chem. 2015;290:142-56 pubmed publisher
  • immunocytochemistry; dogs; fig 3A
Fields I, Shteyn E, Pypaert M, Proux Gillardeaux V, Kang R, Galli T, et al. v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells. J Cell Biol. 2007;177:477-88 pubmed
Huang N, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, et al. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nat Commun. 2017;8:423 pubmed publisher
Jackson M, Ma R, Taylor A, Axton R, Easterbrook J, Kydonaki M, et al. Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells. Stem Cells Transl Med. 2016;5:981-90 pubmed publisher
Giani F, Fiorini C, Wakabayashi A, Ludwig L, Salem R, Jobaliya C, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. 2016;18:73-78 pubmed publisher
Aparicio Prat E, Arnan C, Sala I, Bosch N, Guigó R, Johnson R. DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs. BMC Genomics. 2015;16:846 pubmed publisher
Lee H, Gao X, Barrasa M, Li H, Elmes R, Peters L, et al. PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. Nature. 2015;522:474-7 pubmed publisher
McCracken M, Vatakis D, Dixit D, McLaughlin J, Zack J, Witte O. Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. J Clin Invest. 2015;125:1815-26 pubmed publisher
Ma Y, Wang B, Jiang F, Wang D, Liu H, Yan Y, et al. A feedback loop consisting of microRNA 23a/27a and the ?-like globin suppressors KLF3 and SP1 regulates globin gene expression. Mol Cell Biol. 2013;33:3994-4007 pubmed publisher
Byrne S, Buckett P, Kim J, Luo F, Sanford J, Chen J, et al. Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo. PLoS ONE. 2013;8:e70199 pubmed publisher
Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
Sasaki H, Toda T, Furukawa T, Mawatari Y, Takaesu R, Shimizu M, et al. ?-1,6-Fucosyltransferase (FUT8) inhibits hemoglobin production during differentiation of murine and K562 human erythroleukemia cells. J Biol Chem. 2013;288:16839-47 pubmed publisher
Zhang X, Cruz F, Terry M, Remotti F, Matushansky I. Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming. Oncogene. 2013;32:2249-60, 2260.e1-21 pubmed publisher
Woo A, Kim J, Xu J, Huang H, Cantor A. Role of ZBP-89 in human globin gene regulation and erythroid differentiation. Blood. 2011;118:3684-93 pubmed publisher
Alvares C, Schenk T, Hulkki S, Min T, Vijayaraghavan G, Yeung J, et al. Tyrosine kinase inhibitor insensitivity of non-cycling CD34+ human acute myeloid leukaemia cells with FMS-like tyrosine kinase 3 mutations. Br J Haematol. 2011;154:457-65 pubmed publisher
Pérez Oliva A, Martinez Esparza M, Vicente Fernández J, Corral San Miguel R, García Peñarrubia P, Hernández Caselles T. Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells. Glycobiology. 2011;21:757-70 pubmed publisher
Muranyi A, Dedhar S, Hogge D. Targeting integrin linked kinase and FMS-like tyrosine kinase-3 is cytotoxic to acute myeloid leukemia stem cells but spares normal progenitors. Leuk Res. 2010;34:1358-65 pubmed publisher
Fukuchi K, Steiniger S, Deryugina E, Liu Y, Lowery C, Gloeckner C, et al. Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Mol Pharm. 2010;7:245-53 pubmed publisher
Wenning L, Murphy R. Coupled cellular trafficking and diffusional limitations in delivery of immunotoxins to multicell tumor spheroids. Biotechnol Bioeng. 1999;62:562-75 pubmed
Terng H, Gessner R, Fuchs H, Stahl U, Lang C. Human transferrin receptor is active and plasma membrane-targeted in yeast. FEMS Microbiol Lett. 1998;160:61-7 pubmed
Sutherland R, Delia D, Schneider C, Newman R, Kemshead J, Greaves M. Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. Proc Natl Acad Sci U S A. 1981;78:4515-9 pubmed
Salcedo T, Fleit H. Plasma membrane and intracellular pools of transferrin receptors decline during in vitro cultivation of U937 cells. Cell Prolif. 1991;24:383-401 pubmed
Franco A, Paroli M, Testa U, Benvenuto R, Peschle C, Balsano F, et al. Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes. J Exp Med. 1992;175:1195-205 pubmed
product information
Product Type :
Antibody
Product Name :
CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), eBioscience™
Catalog # :
14-0719-80
Quantity :
25µg
Price :
US 127
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Western Blot: 1:1000
Species :
Human
Clone :
OKT9 (OKT-9)
Isotype :
IgG1, kappa
Storage :
4° C
Description :
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Western Blot: 1:1000
Aliases :
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; TFR1; Tfrc; TR; transferrin receptor; transferrin receptor (p90, CD71); Transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA