CD68 Monoclonal Antibody (eBioY1/82A (Y1/82A)), eBioscience | Invitrogen 14-0689-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (eBioY1/82A (Y1/82A)), eBioscience

catalog :

14-0689-37

quantity :

2 mg

price :

US 1474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eBioY1/82A (Y1/82A)

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

citations: 25

Reference
Le Y, Gao H, Le J, Hornick J, Bleday R, Wee J, et al. VentX promotes tumor specific immunity and efficacy of immune checkpoint inhibitors. iScience. 2024;27:108731 pubmed publisher
Zhang J, Yuan Z, Li X, Wang F, Wei X, Kang Y, et al. Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection. Life Sci Alliance. 2023;6: pubmed publisher
Zhou B, Xu Y, Xu L, Kong Y, Li K, Chen B, et al. Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p. Int J Exp Pathol. 2023;104:292-303 pubmed publisher
Lerouge L, Gries M, Chateau A, Daouk J, Lux F, Rocchi P, et al. Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX®-Design Nanoparticles. Pharmaceutics. 2023;15: pubmed publisher
Gonz xe1 lez Ch xe1 vez S, Chaparro Barrera E, Alvarado J xe1 quez M, Cuevas Mart xed nez R, Ochoa Alb xed ztegui R, Pacheco Tena C. Complete Freund's Adjuvant Induces a Fibroblast-like Synoviocytes (FLS) Metabolic and Migratory Phenotype in Resident Fibroblasts of the Inoculated Footpad at the Earliest Stage of Adjuvant-Induced Arthritis. Cells. 2023;12: pubmed publisher
Wu H, Liu K, Zhang J. LINC00240/miR-155 axis regulates function of trophoblasts and M2 macrophage polarization via modulating oxidative stress-induced pyroptosis in preeclampsia. Mol Med. 2022;28:119 pubmed publisher
Zhang H, Wang Y, Zhao Y, Liu T, Wang Z, Zhang N, et al. PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma. CNS Neurosci Ther. 2022;28:1748-1766 pubmed publisher
Arendt L. Divide and Conquer: Isolating Cell Populations to Investigate How Breast Cancer Risk Factors Alter the Breast Microenvironment. Methods Mol Biol. 2022;2471:271-282 pubmed publisher
Lai C, Tseng P, Chen C, Satria R, Wang Y, Lin C. Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages. J Inflamm Res. 2021;14:5241-5249 pubmed publisher
Cai C, Zeng D, Gao Q, Ma L, Zeng B, Zhou Y, et al. Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis. Sci Rep. 2021;11:13386 pubmed publisher
Schmitz T, Jannasch M, Weigel T, Moseke C, Gbureck U, Groll J, et al. Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages. Materials (Basel). 2020;13: pubmed publisher
Mohamed O, El Bastawisy A, Allahlobi N, Abdellateif M, Zekri A, Shaarawy S, et al. The role of CD68+ macrophage in classical Hodgkin lymphoma patients from Egypt. Diagn Pathol. 2020;15:10 pubmed publisher
Izadi D, Layton T, Williams L, McCann F, Cabrita M, Espirito Santo A, et al. Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis. Sci Adv. 2019;5:eaay0370 pubmed publisher
Li H, Li L, Mei H, Pan G, Wang X, Huang X, et al. Antitumor properties of triptolide: phenotype regulation of macrophage differentiation. Cancer Biol Ther. 2020;21:178-188 pubmed publisher
Sorensen J, Kaluhiokalani J, Hafen P, Deyhle M, Parcell A, Hyldahl R. An altered response in macrophage phenotype following damage in aged human skeletal muscle: implications for skeletal muscle repair. FASEB J. 2019;33:10353-10368 pubmed publisher
Luo Y, Duan H, Qian Y, Feng L, Wu Z, Wang F, et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res. 2017;27:352-372 pubmed publisher
Tsai C, Lin Y, Huang C, Shih C, Tsai Y, Tsao N, et al. Thrombomodulin regulates monocye differentiation via PKC? and ERK1/2 pathway in vitro and in atherosclerotic artery. Sci Rep. 2016;6:38421 pubmed publisher
Garcia Mesa Y, Jay T, Checkley M, Luttge B, Dobrowolski C, Valadkhan S, et al. Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system. J Neurovirol. 2017;23:47-66 pubmed publisher
Broeren M, de Vries M, Bennink M, Arntz O, van Lent P, van der Kraan P, et al. Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane. Arthritis Res Ther. 2016;18:186 pubmed publisher
Zhong Y, Yi C. MicroRNA-720 suppresses M2 macrophage polarization by targeting GATA3. Biosci Rep. 2016;36: pubmed publisher
Chalan P, Bijzet J, Huitema M, Kroesen B, Brouwer E, Boots A. Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis. PLoS ONE. 2015;10:e0132436 pubmed publisher
He L, Marneros A. Doxycycline inhibits polarization of macrophages to the proangiogenic M2-type and subsequent neovascularization. J Biol Chem. 2014;289:8019-28 pubmed publisher
Babu R, Brown A. A consensus surface activation marker signature is partially dependent on human immunodeficiency virus type 1 Nef expression within productively infected macrophages. Retrovirology. 2013;10:155 pubmed publisher
VanSaun M, Mendonsa A, Lee Gorden D. Hepatocellular proliferation correlates with inflammatory cell and cytokine changes in a murine model of nonalchoholic fatty liver disease. PLoS ONE. 2013;8:e73054 pubmed publisher
Prosniak M, Harshyne L, Andrews D, Kenyon L, Bedelbaeva K, Apanasovich T, et al. Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers. Clin Cancer Res. 2013;19:3776-86 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (eBioY1/82A (Y1/82A)), eBioscience

Catalog # :

14-0689-37

Quantity :

2 mg

Price :

US 1474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 ug/test, Immunocytochemistry: 1 ug/mL, Immunohistochemistry (Frozen): Assay-Dependent

Species :

Human

Clone :

eBioY1/82A (Y1/82A)

Isotype :

IgG2b, kappa

Storage :

4 C

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test, Immunocytochemistry: 1 ug/mL, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen