CD68 Monoclonal Antibody (815CU17), eBioscience | Invitrogen 14-0687-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (815CU17), eBioscience

catalog :

14-0687-82

quantity :

100 ug

price :

US 440.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

815CU17

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig 4c	Almishri W, Swain L, D Mello C, Le T, Urbanski S, Nguyen H. ADAM Metalloproteinase Domain 17 Regulates Cholestasis-Associated Liver Injury and Sickness Behavior Development in Mice. Front Immunol. 2021;12:779119 pubmed publisher
	Zhang Y, Cheng S, Zhang M, Zhen L, Pang D, Zhang Q, et al. High-infiltration of tumor-associated macrophages predicts unfavorable clinical outcome for node-negative breast cancer. PLoS ONE. 2013;8:e76147 pubmed publisher
	Gottfried E, Kunz Schughart L, Weber A, Rehli M, Peuker A, Muller A, et al. Expression of CD68 in non-myeloid cell types. Scand J Immunol. 2008;67:453-63 pubmed publisher
	Ramprasad M, Terpstra V, Kondratenko N, Quehenberger O, Steinberg D. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1996;93:14833-8 pubmed

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (815CU17), eBioscience

Catalog # :

14-0687-82

Quantity :

100 ug

Price :

US 440.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 5 ug/ml, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 5 ug/mL

Species :

Human

Clone :

815CU17

Isotype :

IgG1, kappa

Storage :

4 C

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/ml, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 5 ug/mL

Aliases :

CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen

more info or order :

Invitrogen product webpage