CD68 Monoclonal Antibody (FA-11), eBioscience™ | Invitrogen 14-0681-95 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (FA-11), eBioscience™

catalog :

14-0681-95

quantity :

10 mg

price :

3000.00 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

FA-11

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 7

Reference
Tan Y, Li J, Goh C, Lee B, Kwok I, Ng W, et al. Streamlining volumetric multi-channel image cytometry using hue-saturation-brightness-based surface creation. Commun Biol. 2018;1:136 pubmed publisher
Chi B, Wang S, Bi S, Qin W, Wu D, Luo Z, et al. Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia cultures. Exp Ther Med. 2018;15:847-853 pubmed publisher
Ma S, Sun R, Jiang B, Gao J, Deng W, Liu P, et al. L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. Mol Cell Biol. 2017;37: pubmed publisher
Stevens S, von Gise A, VanDusen N, Zhou B, Pu W. Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart. Dev Biol. 2016;413:153-159 pubmed publisher
Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif A, Spinrad A, et al. Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology. Nat Commun. 2015;6:7967 pubmed publisher
Kidder D, Richards H, Lyons P, Crocker P. Sialoadhesin deficiency does not influence the severity of lupus nephritis in New Zealand black x New Zealand white F1 mice. Arthritis Res Ther. 2013;15:R175 pubmed publisher
Fischer M, Davies M, Reider I, Heipertz E, Epler M, Sei J, et al. CD11b?, Ly6G? cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathog. 2011;7:e1002374 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (FA-11), eBioscience™

Catalog # :

14-0681-95

Quantity :

10 mg

Price (USD) :

3000.00 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 5 µg/mL

Species :

Mouse

Clone :

FA-11

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 5 µg/mL

Aliases :

CD68; CD68 antigen; CD68 molecule; Gp110; LAMP4; macrophage antigen CD68; macrosialin; SCARD1; scavenger receptor class D, member 1; similar to CD68 antigen

more info or order :

Invitrogen product webpage