CD66a (CEACAM1) Monoclonal Antibody (CC1), eBioscience | Invitrogen 14-0661-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD66a (CEACAM1) Monoclonal Antibody (CC1), eBioscience

catalog :

14-0661-80

quantity :

25 µg

price :

US 123

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CC1

reactivity :

mouse

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 28

Reference
Nonaka Y, Takeda R, Kano Y, Hoshino D. Short-Term Calorie Restriction Maintains Plasma Insulin Concentrations along with a Reduction in Hepatic Insulin-Degrading Enzyme Levels in db/db Mice. Nutrients. 2021;13: pubmed publisher
Dao T, Utturkar S, Atallah Lanman N, Matosevic S. TIM-3 Expression Is Downregulated on Human NK Cells in Response to Cancer Targets in Synergy with Activation. Cancers (Basel). 2020;12: pubmed publisher
Liszt K, Ley J, Lieder B, Behrens M, Stöger V, Reiner A, et al. Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells. Proc Natl Acad Sci U S A. 2017;114:E6260-E6269 pubmed publisher
Inoue T, Tsai B. Regulated Erlin-dependent release of the B12 transmembrane J-protein promotes ER membrane penetration of a non-enveloped virus. PLoS Pathog. 2017;13:e1006439 pubmed publisher
Abboud Jarrous G, Priya S, Maimon A, Fischman S, Cohen Elisha M, Czerninski R, et al. Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL. Oncotarget. 2017;8:13986-14002 pubmed publisher
Johnson Chacko L, Pechriggl E, Fritsch H, Rask Andersen H, Blumer M, Schrott Fischer A, et al. Neurosensory Differentiation and Innervation Patterning in the Human Fetal Vestibular End Organs between the Gestational Weeks 8-12. Front Neuroanat. 2016;10:111 pubmed
Dhillon R, Parker J, Syed Y, Edgley S, Young A, Fawcett J, et al. Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta Neuropathol Commun. 2016;4:89 pubmed publisher
Jiang M, Liu L, He X, Wang H, Lin W, Wang H, et al. Regulation of PERK-eIF2? signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016;7:12185 pubmed publisher
Walker W, Oehler A, Edinger A, Wagner K, Gunn T. Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy. Biol Cell. 2016;108:324-337 pubmed publisher
Nagao M, Ogata T, Sawada Y, Gotoh Y. Zbtb20 promotes astrocytogenesis during neocortical development. Nat Commun. 2016;7:11102 pubmed publisher
Silva G, Silva J, Diniz T, Lemos V, Cortes S. Endothelial dysfunction in DOCA-salt-hypertensive mice: role of neuronal nitric oxide synthase-derived hydrogen peroxide. Clin Sci (Lond). 2016;130:895-906 pubmed publisher
Hackett A, Lee D, Dawood A, Rodriguez M, Funk L, Tsoulfas P, et al. STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury. Neurobiol Dis. 2016;89:10-22 pubmed publisher
Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-ÎºB signalling instead of B-cell receptor signalling. Hematol Oncol. 2017;35:187-197 pubmed publisher
Kohro Y, Sakaguchi E, Tashima R, Tozaki Saitoh H, Okano H, Inoue K, et al. A new minimally-invasive method for microinjection into the mouse spinal dorsal horn. Sci Rep. 2015;5:14306 pubmed publisher
Tzankov A, Leu N, Muenst S, Juskevicius D, Klingbiel D, Mamot C, et al. Multiparameter analysis of homogeneously R-CHOP-treated diffuse large B cell lymphomas identifies CD5 and FOXP1 as relevant prognostic biomarkers: report of the prospective SAKK 38/07 study. J Hematol Oncol. 2015;8:70 pubmed publisher
Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, et al. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat Neurosci. 2015;18:511-20 pubmed publisher
Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova N, et al. Double minute amplification of mutant PDGF receptor Î± in a mouse glioma model. Sci Rep. 2015;5:8468 pubmed publisher
Kap M, Lam K, Ewing Graham P, Riegman P. A reference image-based method for optimization of clinical immunohistochemistry. Histopathology. 2015;67:193-205 pubmed publisher
Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, et al. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nat Commun. 2014;5:5482 pubmed publisher
Sevcenco S, Haitel A, Ponhold L, Susani M, Fajkovic H, Shariat S, et al. Quantitative apparent diffusion coefficient measurements obtained by 3-Tesla MRI are correlated with biomarkers of bladder cancer proliferative activity. PLoS ONE. 2014;9:e106866 pubmed publisher
Pinheiro C, Roque R, Adriano A, Mendes P, Praça M, Reis I, et al. Optimization of immunocytochemistry in cytology: comparison of two protocols for fixation and preservation on cytospin and smear preparations. Cytopathology. 2015;26:38-43 pubmed publisher
Lysko D, Putt M, Golden J. SDF1 reduces interneuron leading process branching through dual regulation of actin and microtubules. J Neurosci. 2014;34:4941-62 pubmed publisher
Kozlowski C, Jeet S, Beyer J, Guerrero S, Lesch J, Wang X, et al. An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides. Dis Model Mech. 2013;6:855-65 pubmed publisher
Kinkor Z, Sticová E, Sach J, Rychtera J, Skalova A. [Sarcomatoid (metaplastic) spindle cell carcinoma arising in a phylloid tumor with massive squamous metaplasia - a case report and review of the literature]. Cesk Patol. 2012;48:156-60 pubmed
Liu Y, Islam E, Jarvis G, Gray Owen S, Russell M. Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-?-dependent mechanisms. Mucosal Immunol. 2012;5:320-31 pubmed publisher
Thirion G, Feliu A, Coutelier J. CD66a (CEACAM1) expression by mouse natural killer cells. Immunology. 2008;125:535-40 pubmed publisher
Nakagaki K, Nakagaki K, Taguchi F. Receptor-independent spread of a highly neurotropic murine coronavirus JHMV strain from initially infected microglial cells in mixed neural cultures. J Virol. 2005;79:6102-10 pubmed
Turner B, Hemmila E, Beauchemin N, Holmes K. Receptor-dependent coronavirus infection of dendritic cells. J Virol. 2004;78:5486-90 pubmed

product information

Product Type :

Antibody

Product Name :

CD66a (CEACAM1) Monoclonal Antibody (CC1), eBioscience

Catalog # :

14-0661-80

Quantity :

25 µg

Price :

US 123

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1:500

Species :

Mouse

Clone :

CC1

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CEACAM1 is a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1:500

Aliases :

antigen CD66; ATP-dependent taurocolate-carrier protein; bb-1; BGP; BGP1; BGP-1; BGPI; BGPR; Biliary glycoprotein 1; biliary glycoprotein D; bone gamma-carboxyglutamic acid (Gla) protein; carcinoembryonic antigen 1; carcinoembryonic antigen 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Cc1; C-CAM; C-CAM 105; Ccam1; CD66a; CD66a antigen; Cea1; Cea-1; Cea7; Cea-7; CEACAM1; CEA-related cell adhesion molecule 1; CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin); Cell-CAM 105; ecto-ATPase; GP110; hepatitis virus (MHV-4) susceptibility; hepatitis virus receptor; Hv2; Hv-2; mCEA1; Mhv-1; MHVR; MHV-R; MHVR1; mmCGM1; mmCGM1a; mmCGM2; murine hepatitis virus receptor; osteocalcin; pp120; pp120/ecto-ATPase