CD56 (NCAM) Monoclonal Antibody (CMSSB), eBioscience | Invitrogen 14-0567-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD56 (NCAM) Monoclonal Antibody (CMSSB), eBioscience

catalog :

14-0567-95

quantity :

10 mg

price :

US 3705.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CMSSB

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 21

Reference
Santana Hern xe1 ndez S, Suarez Olmos J, Servitja S, Berenguer Molins P, Costa García M, Comerma L, et al. NK cell-triggered CCL5/IFNγ-CXCL9/10 axis underlies the clinical efficacy of neoadjuvant anti-HER2 antibodies in breast cancer. J Exp Clin Cancer Res. 2024;43:10 pubmed publisher
Nawrocki S, Olea J, Villa Celi C, Dadrastoussi H, Wu K, Tsao Wei D, et al. Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial. Clin Cancer Res. 2023;29:5087-5103 pubmed publisher
Hua J, Jiao T, Qiao Y, Zhang S, Xiao T, Zhang Y, et al. Human serum albumin promotes self-renewal and expansion of umbilical cord blood CD34+ hematopoietic stem/progenitor cells. Ann Transl Med. 2023;11:62 pubmed publisher
Juttukonda L, Wachman E, Boateng J, Clarke K, Snyder Cappione J, Taglauer E. The impact of maternal SARS-CoV-2 vaccination and first trimester infection on feto-maternal immune responses. Am J Reprod Immunol. 2022;88:e13625 pubmed publisher
Di Pietro L, Giacalone F, Ragozzino E, Saccone V, Tiberio F, De Bardi M, et al. Non-myogenic mesenchymal cells contribute to muscle degeneration in facioscapulohumeral muscular dystrophy patients. Cell Death Dis. 2022;13:793 pubmed publisher
Sun Q, Wang Y, Ji H, Sun X, Xie S, Chen L, et al. Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma. Cell Death Dis. 2022;13:724 pubmed publisher
Jiang L, Fei H, Jin X, Liu X, Yang C, Li C, et al. Extracellular Vesicle-Mediated Secretion of HLA-E by Trophoblasts Maintains Pregnancy by Regulating the Metabolism of Decidual NK Cells. Int J Biol Sci. 2021;17:4377-4395 pubmed publisher
Louka E, Povinelli B, Rodriguez Meira A, Buck G, Wen W, Wang G, et al. Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia. J Exp Med. 2021;218: pubmed publisher
Black J, McCutcheon S, Dube S, Barrera A, Klann T, Rice G, et al. Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens. Cell Rep. 2020;33:108460 pubmed publisher
He J, Xu Y, Yi M, Gu C, Zhu Y, Hu G. Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain. J Int Med Res. 2020;48:300060519871407 pubmed publisher
Tiwari R, Manzar N, Bhatia V, Yadav A, Nengroo M, Datta D, et al. Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer. Nat Commun. 2020;11:384 pubmed publisher
Pan M, Wu C, Kan J, Li Q, Chang S, Wu C, et al. Impact of FAK Expression on the Cytotoxic Effects of CIK Therapy in Triple-Negative Breast Cancer. Cancers (Basel). 2019;12: pubmed publisher
Choi J, Lee E, Kim S, Park S, Oh S, Kang J, et al. Cytotoxic effects of ex vivo-expanded natural killer cell-enriched lymphocytes (MYJ1633) against liver cancer. BMC Cancer. 2019;19:817 pubmed publisher
Klöss V, Grünvogel O, Wabnitz G, Eigenbrod T, Ehrhardt S, Lasitschka F, et al. Interaction and Mutual Activation of Different Innate Immune Cells Is Necessary to Kill and Clear Hepatitis C Virus-Infected Cells. Front Immunol. 2017;8:1238 pubmed publisher
Yin W, Tong S, Zhang Q, Shao J, Liu Q, Peng H, et al. Functional dichotomy of Vδ2 γδ T cells in chronic hepatitis C virus infections: role in cytotoxicity but not for IFN-γ production. Sci Rep. 2016;6:26296 pubmed publisher
Soh K, Tario J, Colligan S, Maguire O, Pan D, Minderman H, et al. Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins. Curr Protoc Cytom. 2016;75:7.45.1-7.45.33 pubmed publisher
Bhanu N, Sidoli S, Garcia B. Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. Proteomics. 2016;16:448-58 pubmed publisher
Taborda N, GonzÃ¡lez S, Alvarez C, Correa L, Montoya C, Rugeles M. Higher Frequency of NK and CD4+ T-Cells in Mucosa and Potent Cytotoxic Response in HIV Controllers. PLoS ONE. 2015;10:e0136292 pubmed publisher
Barnig C, Cernadas M, Dutile S, Liu X, Perrella M, Kazani S, et al. Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Sci Transl Med. 2013;5:174ra26 pubmed publisher
Sonnenberg G, Monticelli L, Alenghat T, Fung T, Hutnick N, Kunisawa J, et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science. 2012;336:1321-5 pubmed publisher
Zhang S, Crivello A, Offenbacher S, Moretti A, Paquette D, Barros S. Interferon-gamma promoter hypomethylation and increased expression in chronic periodontitis. J Clin Periodontol. 2010;37:953-61 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD56 (NCAM) Monoclonal Antibody (CMSSB), eBioscience

Catalog # :

14-0567-95

Quantity :

10 mg

Price :

US 3705.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 ug/test, Immunohistochemistry (Paraffin): Assay-Dependent

Species :

Human

Clone :

CMSSB

Isotype :

IgG1, kappa

Storage :

4 C

Description :

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test, Immunohistochemistry (Paraffin): Assay-Dependent

Aliases :

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM