CD56 (NCAM) Monoclonal Antibody (5tukon56), eBioscience | Invitrogen 14-0565-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD56 (NCAM) Monoclonal Antibody (5tukon56), eBioscience

catalog :

14-0565-82

quantity :

100 ug

price :

US 250.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5tukon56

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Hayakawa Y, Huntington N, Nutt S, Smyth M. Functional subsets of mouse natural killer cells. Immunol Rev. 2006;214:47-55 pubmed
Pollerberg E, Sadoul R, Goridis C, Schachner M. Selective expression of the 180-kD component of the neural cell adhesion molecule N-CAM during development. J Cell Biol. 1985;101:1921-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD56 (NCAM) Monoclonal Antibody (5tukon56), eBioscience

Catalog # :

14-0565-82

Quantity :

100 ug

Price :

US 250.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1 ug/mL, Western Blot: Assay-Dependent

Species :

Human

Clone :

5tukon56

Isotype :

IgG1, kappa

Storage :

4 C

Description :

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1 ug/mL, Western Blot: Assay-Dependent

Aliases :

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM