CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™ | Invitrogen 14-0549-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™

catalog :

14-0549-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HA58

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, flow cytometry

more info or order :

Invitrogen product webpage

citations: 38

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1	Valentiner U, Knips J, Pries R, Clauditz T, Münscher A, Sauter G, et al. Selectin Binding Sites Are Involved in Cell Adhesive Properties of Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2019;11: pubmed publisher
flow cytometry; human; loading ...; fig 5a	Lim S, Kim J, Jeon S, Shin M, Kwon J, Kim T, et al. Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients. Front Immunol. 2019;10:496 pubmed publisher
flow cytometry; human; loading ...; tbl 1	Monsuur H, Weijers E, Niessen F, Gefen A, Koolwijk P, Gibbs S, et al. Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering. PLoS ONE. 2016;11:e0167056 pubmed publisher
flow cytometry; human; loading ...	Andzinski L, Kasnitz N, Stahnke S, Wu C, Gereke M, von KÃ¶ckritz Blickwede M, et al. Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human. Int J Cancer. 2016;138:1982-93 pubmed publisher
flow cytometry; human	Ziblat A, Domaica C, Spallanzani R, Iraolagoitia X, Rossi L, Avila D, et al. IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness. Eur J Immunol. 2015;45:192-202 pubmed publisher
flow cytometry; human	Miyabe Y, Miyabe C, Iwai Y, Yokoyama W, Sekine C, Sugimoto K, et al. Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid-lysophosphatidic acid receptor 1 cascade. Arthritis Res Ther. 2014;16:461 pubmed publisher
flow cytometry; human; fig 6	Srivastava P, Paluch B, Matsuzaki J, James S, Collamat Lai G, Karbach J, et al. Immunomodulatory action of SGI-110, a hypomethylating agent, in acute myeloid leukemia cells and xenografts. Leuk Res. 2014;38:1332-41 pubmed publisher
flow cytometry; human	Brandau S, Jakob M, Bruderek K, Bootz F, Giebel B, Radtke S, et al. Mesenchymal stem cells augment the anti-bacterial activity of neutrophil granulocytes. PLoS ONE. 2014;9:e106903 pubmed publisher
	Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
	Li C, Liu S, Yan R, Han N, WONG K, Li L. CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer. Theranostics. 2017;7:67-80 pubmed publisher
	Cahall C, Lilly J, Hirschowitz E, Berron B. A Quantitative Perspective on Surface Marker Selection for the Isolation of Functional Tumor Cells. Breast Cancer (Auckl). 2015;9:1-11 pubmed publisher
	Kumar S, Xu J, Kumar R, Lakshmikanthan S, Kapur R, Kofron M, et al. The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation. J Exp Med. 2014;211:1741-58 pubmed publisher
	An N, Andrukhov O, Tang Y, Falkensammer F, Bantleon H, Ouyang X, et al. Effect of nicotine and porphyromonas gingivalis lipopolysaccharide on endothelial cells in vitro. PLoS ONE. 2014;9:e96942 pubmed publisher
	Stoler Barak L, Barzilai S, Zauberman A, Alon R. Transendothelial migration of effector T cells across inflamed endothelial barriers does not require heparan sulfate proteoglycans. Int Immunol. 2014;26:315-24 pubmed publisher
	Compeer E, Flinsenberg T, Boon L, Hoekstra M, Boes M. Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation. J Biol Chem. 2014;289:520-8 pubmed publisher
	Evani S, Prabhu R, Gnanaruban V, Finol E, Ramasubramanian A. Monocytes mediate metastatic breast tumor cell adhesion to endothelium under flow. FASEB J. 2013;27:3017-29 pubmed publisher
	Lo Schiavo V, Robert P, Limozin L, Bongrand P. Quantitative modeling assesses the contribution of bond strengthening, rebinding and force sharing to the avidity of biomolecule interactions. PLoS ONE. 2012;7:e44070 pubmed
	Qin Y, Li Y, Liu W, Tian R, Guo Q, Li S, et al. Penicillium marneffei-stimulated dendritic cells enhance HIV-1 trans-infection and promote viral infection by activating primary CD4+ T cells. PLoS ONE. 2011;6:e27609 pubmed publisher
	Robert P, Nicolas A, Aranda Espinoza S, Bongrand P, Limozin L. Minimal encounter time and separation determine ligand-receptor binding in cell adhesion. Biophys J. 2011;100:2642-51 pubmed publisher
	Charoenphol P, Mocherla S, Bouïs D, Namdee K, Pinsky D, Eniola Adefeso O. Targeting therapeutics to the vascular wall in atherosclerosis--carrier size matters. Atherosclerosis. 2011;217:364-70 pubmed publisher
	Uldrick T, Polizzotto M, Aleman K, O Mahony D, Wyvill K, Wang V, et al. High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy. Blood. 2011;117:6977-86 pubmed publisher
	Kina K, Masuda H, Nakayama H, Nagatsuka Y, Nabetani T, Hirabayashi Y, et al. The novel neutrophil differentiation marker phosphatidylglucoside mediates neutrophil apoptosis. J Immunol. 2011;186:5323-32 pubmed publisher
	Allaeys I, Rusu D, Picard S, Pouliot M, Borgeat P, Poubelle P. Osteoblast retraction induced by adherent neutrophils promotes osteoclast bone resorption: implication for altered bone remodeling in chronic gout. Lab Invest. 2011;91:905-20 pubmed publisher
	Kim T, Kim N, Kang H, Kim E, Kim S, Ahn H, et al. FK506 causes cellular and functional defects in human natural killer cells. J Leukoc Biol. 2010;88:1089-97 pubmed publisher
	Kawamata N, Xu B, Nishijima H, Aoyama K, Kusumoto M, Takeuchi T, et al. Expression of endothelia and lymphocyte adhesion molecules in bronchus-associated lymphoid tissue (BALT) in adult human lung. Respir Res. 2009;10:97 pubmed publisher
	Rydberg C, Mansson A, Uddman R, Riesbeck K, Cardell L. Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas. Immunology. 2009;128:e600-11 pubmed publisher
	Wang J, Kwas C, Wu L. Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission. J Virol. 2009;83:4195-204 pubmed publisher
	Okumura S, Yuki K, Kobayashi R, Okamura S, Ohmori K, Saito H, et al. Hyperexpression of NOD2 in intestinal mast cells of Crohn's disease patients: preferential expression of inflammatory cell-recruiting molecules via NOD2 in mast cells. Clin Immunol. 2009;130:175-85 pubmed publisher
	Robert P, Sengupta K, Puech P, Bongrand P, Limozin L. Tuning the formation and rupture of single ligand-receptor bonds by hyaluronan-induced repulsion. Biophys J. 2008;95:3999-4012 pubmed publisher
	Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed publisher
	Mandron M, Ariès M, Boralevi F, Martin H, Charveron M, Taieb A, et al. Age-related differences in sensitivity of peripheral blood monocytes to lipopolysaccharide and Staphylococcus aureus toxin B in atopic dermatitis. J Invest Dermatol. 2008;128:882-9 pubmed
	Nakhaei Nejad M, Hussain A, Zhang Q, Murray A. Endothelial PI 3-kinase activity regulates lymphocyte diapedesis. Am J Physiol Heart Circ Physiol. 2007;293:H3608-16 pubmed
	Schierloh P, Yokobori N, Aleman M, Landoni V, Geffner L, Musella R, et al. Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy. Infect Immun. 2007;75:5325-37 pubmed
	Yotsui T, Yasuda O, Kawamoto H, Higuchi M, Chihara Y, Umemoto E, et al. Aspirin prevents adhesion of T lymphoblasts to vascular smooth muscle cells. FEBS Lett. 2007;581:427-32 pubmed
	Kim J, Choi E, Shin H, Kim C, Hwang S, Kim S, et al. Characterization of monoclonal antibody specific to the Z39Ig protein, a member of immunoglobulin superfamily. Immunol Lett. 2005;99:153-61 pubmed
	Kanwar J, Berg R, Yang Y, Kanwar R, Ching L, Sun X, et al. Requirements for ICAM-1 immunogene therapy of lymphoma. Cancer Gene Ther. 2003;10:468-76 pubmed
	Bao J, Sato K, Li M, Gao Y, Abid R, Aird W, et al. PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated I kappa B alpha degradation. Am J Physiol Heart Circ Physiol. 2001;281:H2612-8 pubmed
	Davis D, Chiu I, Fassett M, Cohen G, Mandelboim O, Strominger J. The human natural killer cell immune synapse. Proc Natl Acad Sci U S A. 1999;96:15062-7 pubmed

product information

Product Type :

Antibody

Product Name :

CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™

Catalog # :

14-0549-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

HA58

Isotype :

IgG1, kappa

Storage :

4° C

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly-47; major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54

more info or order :

Invitrogen product webpage