CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™ | Invitrogen 14-0549-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™

catalog :

14-0549-80

quantity :

25 µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HA58

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, flow cytometry

citations: 9

Reference
Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
Li C, Liu S, Yan R, Han N, WONG K, Li L. CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer. Theranostics. 2017;7:67-80 pubmed publisher
Andzinski L, Kasnitz N, Stahnke S, Wu C, Gereke M, von KÃ¶ckritz Blickwede M, et al. Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human. Int J Cancer. 2016;138:1982-93 pubmed publisher
Cahall C, Lilly J, Hirschowitz E, Berron B. A Quantitative Perspective on Surface Marker Selection for the Isolation of Functional Tumor Cells. Breast Cancer (Auckl). 2015;9:1-11 pubmed publisher
Kumar S, Xu J, Kumar R, Lakshmikanthan S, Kapur R, Kofron M, et al. The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation. J Exp Med. 2014;211:1741-58 pubmed publisher
An N, Andrukhov O, Tang Y, Falkensammer F, Bantleon H, Ouyang X, et al. Effect of nicotine and porphyromonas gingivalis lipopolysaccharide on endothelial cells in vitro. PLoS ONE. 2014;9:e96942 pubmed publisher
Kawamata N, Xu B, Nishijima H, Aoyama K, Kusumoto M, Takeuchi T, et al. Expression of endothelia and lymphocyte adhesion molecules in bronchus-associated lymphoid tissue (BALT) in adult human lung. Respir Res. 2009;10:97 pubmed publisher
Robert P, Sengupta K, Puech P, Bongrand P, Limozin L. Tuning the formation and rupture of single ligand-receptor bonds by hyaluronan-induced repulsion. Biophys J. 2008;95:3999-4012 pubmed publisher
Davis D, Chiu I, Fassett M, Cohen G, Mandelboim O, Strominger J. The human natural killer cell immune synapse. Proc Natl Acad Sci U S A. 1999;96:15062-7 pubmed

product information

Product Type :

Antibody

Product Name :

CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™

Catalog # :

14-0549-80

Quantity :

25 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

HA58

Isotype :

IgG1, kappa

Storage :

4° C

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; intercellular adhesion molecule-like; LOC100345640; Ly-47; Major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54