CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), eBioscience™ | Invitrogen 14-0541-81 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), eBioscience™

catalog :

14-0541-81

quantity :

50 µg

price :

US 64

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

YN1/1.7.4

reactivity :

mouse

application :

immunohistochemistry, neutralization, flow cytometry

citations: 22

Reference
Kanitz A, Syed A, Kaji K, Zavolan M. Conserved regulation of RNA processing in somatic cell reprogramming. BMC Genomics. 2019;20:100 pubmed publisher
Deloch L, Rückert M, Fietkau R, Frey B, Gaipl U. Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints. Int J Mol Sci. 2018;19: pubmed publisher
Pincha N, Hajam E, Badarinath K, Batta S, Masudi T, Dey R, et al. PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest. 2018;128:1807-1819 pubmed publisher
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed publisher
Xiong Y, Brinkman C, Famulski K, Mongodin E, Lord C, Hippen K, et al. A robust in vitro model for trans-lymphatic endothelial migration. Sci Rep. 2017;7:1633 pubmed publisher
Arokiasamy S, Zakian C, Dilliway J, Wang W, Nourshargh S, Voisin M. Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation. Sci Rep. 2017;7:44189 pubmed publisher
Beard R, Yang X, Meegan J, Overstreet J, Yang C, Elliott J, et al. Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome. Nat Commun. 2016;7:12823 pubmed publisher
Chantzoura E, Skylaki S, Menendez S, Kim S, Johnsson A, Linnarsson S, et al. Reprogramming Roadblocks Are System Dependent. Stem Cell Reports. 2015;5:350-64 pubmed publisher
Harding M, Zhang K, Conly J, Kubes P. Neutrophil crawling in capillaries; a novel immune response to Staphylococcus aureus. PLoS Pathog. 2014;10:e1004379 pubmed publisher
Larsen J, Dall M, Antvorskov J, Weile C, Engkilde K, Josefsen K, et al. Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion. Eur J Immunol. 2014;44:3056-67 pubmed publisher
O MALLEY J, Skylaki S, Iwabuchi K, Chantzoura E, Ruetz T, Johnsson A, et al. High-resolution analysis with novel cell-surface markers identifies routes to iPS cells. Nature. 2013;499:88-91 pubmed publisher
Hossain M, Qadri S, Su Y, Liu L. ICAM-1-mediated leukocyte adhesion is critical for the activation of endothelial LSP1. Am J Physiol Cell Physiol. 2013;304:C895-904 pubmed publisher
Proebstl D, Voisin M, Woodfin A, Whiteford J, D Acquisto F, Jones G, et al. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med. 2012;209:1219-34 pubmed publisher
Otsuka A, Kubo M, Honda T, Egawa G, Nakajima S, Tanizaki H, et al. Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity. PLoS ONE. 2011;6:e25538 pubmed publisher
Birbach A, Eisenbarth D, Kozakowski N, Ladenhauf E, Schmidt Supprian M, Schmid J. Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor model. Neoplasia. 2011;13:692-703 pubmed
Norling L, Spite M, Yang R, Flower R, Perretti M, Serhan C. Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. J Immunol. 2011;186:5543-7 pubmed publisher
Yao L, Baluk P, Feng J, McDonald D. Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways. Am J Pathol. 2010;176:1525-41 pubmed publisher
Huggins A, Paschalidis N, Flower R, Perretti M, D Acquisto F. Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J. 2009;23:985-96 pubmed publisher
Sumagin R, Lomakina E, Sarelius I. Leukocyte-endothelial cell interactions are linked to vascular permeability via ICAM-1-mediated signaling. Am J Physiol Heart Circ Physiol. 2008;295:H969-H977 pubmed publisher
Sumagin R, Brown C, Sarelius I, King M. Microvascular endothelial cells exhibit optimal aspect ratio for minimizing flow resistance. Ann Biomed Eng. 2008;36:580-5 pubmed publisher
Togbe D, Schofield L, Grau G, Schnyder B, Boissay V, Charron S, et al. Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol. 2007;170:1640-8 pubmed
Zhou J, Friend D, Feldweg A, Daheshia M, Li L, Austen K, et al. Prevention of lipopolysaccharide-induced microangiopathy by gp49B1: evidence for an important role for gp49B1 expression on neutrophils. J Exp Med. 2003;198:1243-51 pubmed

product information

Product Type :

Antibody

Product Name :

CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), eBioscience™

Catalog # :

14-0541-81

Quantity :

50 µg

Price :

US 64

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent

Species :

Mouse

Clone :

YN1/1.7.4

Isotype :

IgG2b, kappa

Storage :

4° C

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; intercellular adhesion molecule-like; LOC100345640; Ly-47; Major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54