This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), eBioscience™
catalog :
14-0519-80
quantity :
25µg
price :
US 53.75
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
23C6
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 20 ug/ml; fig 6
Chen W, Cao Z, Sugaya S, Lopez M, Sendra V, Laver N, et al. Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3. Nat Commun. 2016;7:11302 pubmed publisher
SoRelle E, Liba O, Campbell J, Dalal R, Zavaleta C, de la Zerda A. A hyperspectral method to assay the microphysiological fates of nanomaterials in histological samples. elife. 2016;5: pubmed publisher
Jun J, Kim K, Lau L. The matricellular protein CCN1 mediates neutrophil efferocytosis in cutaneous wound healing. Nat Commun. 2015;6:7386 pubmed publisher
Lescarbeau R, Seib F, Prewitz M, Werner C, Kaplan D. In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors. PLoS ONE. 2012;7:e40372 pubmed publisher
Sekine C, Koyanagi A, Koyama N, Hozumi K, Chiba S, Yagita H. Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes. Arthritis Res Ther. 2012;14:R45 pubmed publisher
Mor Cohen R, Rosenberg N, Einav Y, Zelzion E, Landau M, Mansour W, et al. Unique disulfide bonds in epidermal growth factor (EGF) domains of ?3 affect structure and function of ?IIb?3 and ?v?3 integrins in different manner. J Biol Chem. 2012;287:8879-91 pubmed publisher
Mougiakakos D, Okita R, Ando T, Dürr C, Gadiot J, Ichikawa J, et al. High expression of GCLC is associated with malignant melanoma of low oxidative phenotype and predicts a better prognosis. J Mol Med (Berl). 2012;90:935-44 pubmed publisher
Kalkunte S, Lai Z, Tewari N, Chichester C, Romero R, Padbury J, et al. In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts. Placenta. 2008;29:871-8 pubmed publisher
Cao L, Du P, Jiang S, Jin G, Huang Q, Hua Z. Enhancement of antitumor properties of TRAIL by targeted delivery to the tumor neovasculature. Mol Cancer Ther. 2008;7:851-61 pubmed publisher
Aleman M, de la Barrera S, Schierloh P, Yokobori N, Baldini M, Musella R, et al. Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on the dendritic cell-mediated immune response. Eur J Immunol. 2007;37:1524-37 pubmed
product information
Product Type :
Antibody
Product Name :
CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), eBioscience™
Catalog # :
14-0519-80
Quantity :
25µg
Price :
US 53.75
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1 µg/test, Immunohistochemistry (Frozen): Assay-Dependent
Species :
Human
Clone :
23C6
Isotype :
IgG1, kappa
Storage :
4° C
Description :
MA1-33578 recognized the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/test, Immunohistochemistry (Frozen): Assay-Dependent
Aliases :
ITGAV, ITGB3, CD51, MSK8, VNRA, VTNR, integrin alpha-V, integrin alphaVbeta3, antigen CD51, vitronectin receptor subunit alpha, CD61, GP3A, GPIIIa
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA