| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; mouse; loading ...; fig 3f
- immunohistochemistry; mouse; loading ...; fig 3g, s4b
| Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 3c
- flow cytometry; mouse; loading ...; fig 2e
| Hayakawa M, Sakata A, Hayakawa H, Matsumoto H, Hiramoto T, Kashiwakura Y, et al. Characterization and visualization of murine coagulation factor VIII-producing cells in vivo. Sci Rep. 2021;11:14824 pubmed publisher |
- immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig s6g
| Dá Mesquita S, Herz J, Wall M, Dykstra T, de Lima K, Norris G, et al. Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology. Sci Adv. 2021;7: pubmed publisher |
- immunohistochemistry; mouse; 1:100; fig 2e
| Chelvanambi M, Fecek R, Taylor J, Storkus W. STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment. J Immunother Cancer. 2021;9: pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 5c
| Gancz D, Raftrey B, Perlmoter G, Mar n Juez R, Semo J, Matsuoka R, et al. Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration. elife. 2019;8: pubmed publisher |
- immunohistochemistry; mouse; 1:200-1:1000; loading ...; fig 3a
| Shibata Germanos S, Goodman J, Grieg A, Trivedi C, Benson B, Foti S, et al. Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges. Acta Neuropathol. 2020;139:383-401 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 2s1a
| Simmons S, Sasaki N, Umemoto E, Uchida Y, Fukuhara S, Kitazawa Y, et al. High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node. elife. 2019;8: pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 2a
| Meyers J, Winans B, Kelsaw E, Murthy A, Gerber S, Lawrence B. Environmental cues received during development shape dendritic cell responses later in life. PLoS ONE. 2018;13:e0207007 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1a
| Dá Mesquita S, Louveau A, Vaccari A, Smirnov I, Cornelison R, Kingsmore K, et al. Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. Nature. 2018;560:185-191 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 9b
| Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 3a
- flow cytometry; mouse
| Jordan Williams K, Ramanujam N, Farr A, Ruddell A. The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses. PLoS ONE. 2016;11:e0156079 pubmed publisher |
- immunohistochemistry; mouse; fig 9
| Munger S, Geng X, Srinivasan R, Witte M, Paul D, Simon A. Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016;412:173-90 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; fig 1
| Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 10a
| Peske J, Thompson E, Gemta L, Baylis R, Fu Y, Engelhard V. Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity. Nat Commun. 2015;6:7114 pubmed publisher |
- immunohistochemistry; mouse; 1:500; fig 2
| Miller C, Hartigan O Connor D, Lee M, Laidlaw G, Cornelissen I, Matloubian M, et al. IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int Immunol. 2013;25:471-83 pubmed publisher |
| Choi C, Jeong Y, Park K, Kim M, Kim S, Jo H, et al. TM4SF19-mediated control of lysosomal activity in macrophages contributes to obesity-induced inflammation and metabolic dysfunction. Nat Commun. 2024;15:2779 pubmed publisher |
| Zhang Q, Chen Y, Li Y, Feng Z, Liang L, Hao X, et al. Neutrophil extracellular trap-mediated impairment of meningeal lymphatic drainage exacerbates secondary hydrocephalus after intraventricular hemorrhage. Theranostics. 2024;14:1909-1938 pubmed publisher |
| Hog P, Kuntschar S, Rappl P, Huard A, Weigert A, Br xfc ne B, et al. Prostaglandin E2 Boosts the Hyaluronan-Mediated Increase in Inflammatory Response to Lipopolysaccharide by Enhancing Lyve1 Expression. Biology (Basel). 2023;12: pubmed publisher |
| Chovatiya G, Li K, Li J, Ghuwalewala S, Tumbar T. Alk1 acts in non-endothelial VE-cadherin+ perineurial cells to maintain nerve branching during hair homeostasis. Nat Commun. 2023;14:5623 pubmed publisher |
| Wang J, Rattner A, Nathans J. Bacterial meningitis in the early postnatal mouse studied at single-cell resolution. elife. 2023;12: pubmed publisher |
| Li K, Chovatiya G, Ko D, Sureshbabu S, Tumbar T. Blood endothelial ALK1-BMP4 signaling axis regulates adult hair follicle stem cell activation. EMBO J. 2023;42:e112196 pubmed publisher |
| Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, et al. CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023;42:112092 pubmed publisher |
| Siret C, van Lessen M, Bavais J, Jeong H, Reddy Samawar S, Kapupara K, et al. Deciphering the heterogeneity of the Lyve1+ perivascular macrophages in the mouse brain. Nat Commun. 2022;13:7366 pubmed publisher |
| Chen H, Chew G, Devapragash N, Loh J, Huang K, Guo J, et al. The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis. Nat Commun. 2022;13:7375 pubmed publisher |
| Biswas A, Singh S, Kartha G, Khurana S. Immuno-localization of definitive hematopoietic stem cells in the vascular niche of mouse fetal liver. STAR Protoc. 2022;3:101580 pubmed publisher |
| Shen T, Wu Y, Wang X, Wang Z, Li E, Zhou C, et al. Activating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome. Exp Mol Med. 2022;54:1486-1501 pubmed publisher |
| Niec R, Chu T, Schernthanner M, Gur Cohen S, Hidalgo L, Pasolli H, et al. Lymphatics act as a signaling hub to regulate intestinal stem cell activity. Cell Stem Cell. 2022;29:1067-1082.e18 pubmed publisher |
| Kiani Shabestari S, Morabito S, Danhash E, McQuade A, Sanchez J, Miyoshi E, et al. Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice. Cell Rep. 2022;39:110961 pubmed publisher |
| Kobayashi D, Sugiura Y, Umemoto E, Takeda A, Ueta H, Hayasaka H, et al. Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes. Front Immunol. 2021;12:786595 pubmed publisher |
| Menzel L, Zschummel M, Crowley T, Franke V, Grau M, Ulbricht C, et al. Lymphocyte access to lymphoma is impaired by high endothelial venule regression. Cell Rep. 2021;37:109878 pubmed publisher |
| Zhang D, Huang J, Sun X, Chen H, Huang S, Yang J, et al. Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway. Nat Commun. 2021;12:4391 pubmed publisher |
| Okuniewska M, Fang V, Baeyens A, Raghavan V, Lee J, Littman D, et al. SPNS2 enables T cell egress from lymph nodes during an immune response. Cell Rep. 2021;36:109368 pubmed publisher |
| Nishina T, Deguchi Y, Ohshima D, Takeda W, Ohtsuka M, Shichino S, et al. Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer. Nat Commun. 2021;12:2281 pubmed publisher |
| Nguyen S, Ahn S, Greenberg J, Collaer B, Agnew D, Arora R, et al. Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo. Sci Rep. 2021;11:4217 pubmed publisher |
| Hofmann J, Gadjalova I, Mishra R, Ruland J, Keppler S. Efficient Tissue Clearing and Multi-Organ Volumetric Imaging Enable Quantitative Visualization of Sparse Immune Cell Populations During Inflammation. Front Immunol. 2020;11:599495 pubmed publisher |
| Alexander J, Seua A, Arroyo L, Ray P, Wangzhou A, Hei x3b2 L xfc ckemann L, et al. Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits. Theranostics. 2021;11:3109-3130 pubmed publisher |
| Bolte A, Dutta A, Hurt M, Smirnov I, Kovacs M, McKee C, et al. Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nat Commun. 2020;11:4524 pubmed publisher |
| Shrestha S, Cho W, Stump B, Imani J, Lamattina A, Louis P, et al. FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. Mol Med. 2020;26:75 pubmed publisher |
| Chen J, Wang L, Xu H, Xing L, Zhuang Z, Zheng Y, et al. Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage. Nat Commun. 2020;11:3159 pubmed publisher |
| Li X, Karras P, Torres R, Rambow F, van den Oord J, Marine J, et al. Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites. Cell Rep. 2020;31:107765 pubmed publisher |
| Elham E, Wumaier R, Wang C, Luo X, Chen T, Zhong N. Anatomic evidence shows that lymphatic drainage exists in the pituitary to loop the cerebral lymphatic circulation. Med Hypotheses. 2020;143:109898 pubmed publisher |
| Liu T, Yang L, Han X, Ding X, Li J, Yang J. Local sympathetic innervations modulate the lung innate immune responses. Sci Adv. 2020;6:eaay1497 pubmed publisher |
| Wang X, Lou N, Eberhardt A, Yang Y, Kusk P, Xu Q, et al. An ocular glymphatic clearance system removes β-amyloid from the rodent eye. Sci Transl Med. 2020;12: pubmed publisher |
| Hu X, Deng Q, Ma L, Li Q, Chen Y, Liao Y, et al. Meningeal lymphatic vessels regulate brain tumor drainage and immunity. Cell Res. 2020;30:229-243 pubmed publisher |
| Song J, Chen W, Cui X, Huang Z, Wen D, Yang Y, et al. CCBE1 promotes tumor lymphangiogenesis and is negatively regulated by TGFβ signaling in colorectal cancer. Theranostics. 2020;10:2327-2341 pubmed publisher |
| Etzerodt A, Moulin M, Doktor T, Delfini M, Mossadegh Keller N, Bajenoff M, et al. Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer. J Exp Med. 2020;217: pubmed publisher |
| Glinskii O, Huxley V, Xie L, Bunyak F, Palaniappan K, Glinsky V. Complex Non-sinus-associated Pachymeningeal Lymphatic Structures: Interrelationship With Blood Microvasculature. Front Physiol. 2019;10:1364 pubmed publisher |
| Suh S, Choe K, Hong S, Jeong S, Makinen T, Kim K, et al. Gut microbiota regulates lacteal integrity by inducing VEGF-C in intestinal villus macrophages. EMBO Rep. 2019;20: pubmed publisher |
| Hsu M, Rayasam A, Kijak J, Choi Y, Harding J, Marcus S, et al. Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells. Nat Commun. 2019;10:229 pubmed publisher |
| Zhou N, Liu K, Sun Y, Cao Y, Yang J. Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition. Protein Cell. 2019;10:87-103 pubmed publisher |
| Huppé C, Blais Lecours P, Lechasseur A, Gendron D, Lemay A, Bissonnette E, et al. A sphingosine-1-phosphate receptor 1 agonist inhibits tertiary lymphoid tissue reactivation and hypersensitivity in the lung. Mucosal Immunol. 2018;11:112-119 pubmed publisher |
| Arokiasamy S, Zakian C, Dilliway J, Wang W, Nourshargh S, Voisin M. Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation. Sci Rep. 2017;7:44189 pubmed publisher |
| Chucair Elliott A, Carr M, Carr D. Long-term consequences of topical dexamethasone treatment during acute corneal HSV-1 infection on the immune system. J Leukoc Biol. 2017;101:1253-1261 pubmed publisher |
| Wang W, Wang H, Zhou X, Li X, Sun W, Dellinger M, et al. Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice. J Bone Miner Res. 2017;32:939-950 pubmed publisher |
| Munger S, Davis M, Simon A. Defective lymphatic valve development and chylothorax in mice with a lymphatic-specific deletion of Connexin43. Dev Biol. 2017;421:204-218 pubmed publisher |
| Gardenier J, Hespe G, Kataru R, Savetsky I, Torrisi J, Nores G, et al. Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema. JCI Insight. 2016;1:e84095 pubmed publisher |
| Shinoda K, Hirahara K, Iinuma T, Ichikawa T, Suzuki A, Sugaya K, et al. Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation. Proc Natl Acad Sci U S A. 2016;113:E2842-51 pubmed publisher |
| Liang Q, Ju Y, Chen Y, Wang W, Li J, Zhang L, et al. Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice. Arthritis Res Ther. 2016;18:62 pubmed publisher |
| Lua I, Li Y, Zagory J, WANG K, French S, Sévigny J, et al. Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers. J Hepatol. 2016;64:1137-1146 pubmed publisher |
| Chen H, Poduri A, Numi H, Kivela R, Saharinen P, McKay A, et al. VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest. 2014;124:4899-914 pubmed publisher |
| Kizhatil K, Ryan M, Marchant J, Henrich S, John S. Schlemm's canal is a unique vessel with a combination of blood vascular and lymphatic phenotypes that forms by a novel developmental process. PLoS Biol. 2014;12:e1001912 pubmed publisher |
| Riol Blanco L, Ordovas Montanes J, Perro M, Naval E, Thiriot A, Alvarez D, et al. Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation. Nature. 2014;510:157-61 pubmed publisher |
| Cogger V, Svistounov D, Warren A, Zykova S, Melvin R, Solon Biet S, et al. Liver aging and pseudocapillarization in a Werner syndrome mouse model. J Gerontol A Biol Sci Med Sci. 2014;69:1076-86 pubmed publisher |
| Salnikova O, Breuhahn K, Hartmann N, Schmidt J, Ryschich E. Endothelial plasticity governs the site-specific leukocyte recruitment in hepatocellular cancer. Int J Cancer. 2013;133:2372-82 pubmed publisher |
| Corbitt N, Kimura S, Isse K, Specht S, Chedwick L, Rosborough B, et al. Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation. Am J Pathol. 2013;182:180-91 pubmed publisher |
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| Joo H, Choi D, Lim J, Park J, Lee S, Song S, et al. ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells. Blood. 2012;120:2733-44 pubmed |
| Nakayama Y, Bromberg J. Lymphotoxin-beta receptor blockade induces inflammation and fibrosis in tolerized cardiac allografts. Am J Transplant. 2012;12:2322-34 pubmed publisher |
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| Vigl B, Aebischer D, Nitschké M, Iolyeva M, Röthlin T, Antsiferova O, et al. Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner. Blood. 2011;118:205-15 pubmed publisher |
| Furuya M, Kirschbaum S, Paulovich A, Pauli B, Zhang H, Alexander J, et al. Lymphatic endothelial murine chloride channel calcium-activated 1 is a ligand for leukocyte LFA-1 and Mac-1. J Immunol. 2010;185:5769-77 pubmed publisher |
| Harada K, Yamazaki T, Iwata C, Yoshimatsu Y, Sase H, Mishima K, et al. Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis. J Cell Sci. 2009;122:3923-30 pubmed publisher |
| Zumsteg A, Baeriswyl V, Imaizumi N, Schwendener R, Ruegg C, Christofori G. Myeloid cells contribute to tumor lymphangiogenesis. PLoS ONE. 2009;4:e7067 pubmed publisher |
| Luong M, Tam J, Lin Q, Hagendoorn J, Moore K, Padera T, et al. Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice. J Cell Physiol. 2009;219:430-7 pubmed publisher |
| Jiang S, Bailey A, Goldman D, Swain J, Wong M, Streeter P, et al. Hematopoietic stem cells contribute to lymphatic endothelium. PLoS ONE. 2008;3:e3812 pubmed publisher |
| Hirashima M, Sano K, Morisada T, Murakami K, Rossant J, Suda T. Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev Biol. 2008;316:149-59 pubmed publisher |
| Mishima K, Watabe T, Saito A, Yoshimatsu Y, Imaizumi N, Masui S, et al. Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mol Biol Cell. 2007;18:1421-9 pubmed |
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