product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD39 Monoclonal Antibody (eBioA1 (A1)), eBioscience
catalog :
14-0399-82
quantity :
100 ug
price :
US 278.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
eBioA1 (A1)
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 30
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2e
Boardman D, Philippeos C, Fruhwirth G, Ibrahim M, Hannen R, Cooper D, et al. Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection. Am J Transplant. 2017;17:931-943 pubmed publisher
  • flow cytometry; mouse; fig s1
Wensveen F, Jelenčić V, Valentić S, Šestan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed publisher
  • flow cytometry; human; fig 1
Cernea S, Herold K. Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies. Clin Immunol. 2010;134:121-9 pubmed publisher
Swatler J, Targo x144 ska A, Turos Korgul L, Mosieniak G, Piwocka K. Protocol for isolation of tumor-derived extracellular vesicles and functional studies on human T cell subsets. STAR Protoc. 2024;5:103011 pubmed publisher
Goncharov M, Bryushkova E, Sharaev N, Skatova V, Baryshnikova A, Sharonov G, et al. Pinpointing the tumor-specific T cells via TCR clusters. elife. 2022;11: pubmed publisher
Duhen R, Ballesteros Merino C, Frye A, Tran E, Rajamanickam V, Chang S, et al. Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells. Nat Commun. 2021;12:1047 pubmed publisher
Spatola B, Lerner A, Wong C, dela Cruz T, Welch M, Fung W, et al. Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism. MAbs. 2020;12:1838036 pubmed publisher
Schroeder J, Puntigam L, Hofmann L, Jeske S, Beccard I, Doescher J, et al. Circulating Exosomes Inhibit B Cell Proliferation and Activity. Cancers (Basel). 2020;12: pubmed publisher
Beccard I, Hofmann L, Schroeder J, Ludwig S, Laban S, Brunner C, et al. Immune Suppressive Effects of Plasma-Derived Exosome Populations in Head and Neck Cancer. Cancers (Basel). 2020;12: pubmed publisher
Karlsson J, Nilsson L, Mitra S, Alsén S, Shelke G, Sah V, et al. Molecular profiling of driver events in metastatic uveal melanoma. Nat Commun. 2020;11:1894 pubmed publisher
Yero A, Farnos O, Rabezanahary H, Racine G, Estaquier J, Jenabian M. Differential Dynamics of Regulatory T-Cell and Th17 Cell Balance in Mesenteric Lymph Nodes and Blood following Early Antiretroviral Initiation during Acute Simian Immunodeficiency Virus Infection. J Virol. 2019;93: pubmed publisher
de Lourdes Mora García M, López Cisneros S, Gutiérrez Serrano V, García Rocha R, Weiss Steider B, Hernández Montes J, et al. HPV-16 Infection Is Associated with a High Content of CD39 and CD73 Ectonucleotidases in Cervical Samples from Patients with CIN-1. Mediators Inflamm. 2019;2019:4651627 pubmed publisher
Ziebart A, Huber U, Jeske S, Laban S, Doescher J, Hoffmann T, et al. The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma. Oncotarget. 2018;9:5834-5847 pubmed publisher
Philippeos C, Telerman S, Oulès B, Pisco A, Shaw T, Elgueta R, et al. Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations. J Invest Dermatol. 2018;138:811-825 pubmed publisher
Muller L, Mitsuhashi M, Simms P, Gooding W, Whiteside T. Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets. Sci Rep. 2016;6:20254 pubmed publisher
Bastid J, Regairaz A, Bonnefoy N, Déjou C, Giustiniani J, Laheurte C, et al. Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity. Cancer Immunol Res. 2015;3:254-65 pubmed publisher
Yoshida O, Kimura S, Jackson E, Robson S, Geller D, Murase N, et al. CD39 expression by hepatic myeloid dendritic cells attenuates inflammation in liver transplant ischemia-reperfusion injury in mice. Hepatology. 2013;58:2163-75 pubmed publisher
Nanzer A, Chambers E, Ryanna K, Richards D, Black C, Timms P, et al. Enhanced production of IL-17A in patients with severe asthma is inhibited by 1?,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion. J Allergy Clin Immunol. 2013;132:297-304.e3 pubmed publisher
Dokić J, Tomic S, Markovic M, Milosavljević P, Colic M. Mesenchymal stem cells from periapical lesions modulate differentiation and functional properties of monocyte-derived dendritic cells. Eur J Immunol. 2013;43:1862-72 pubmed publisher
Lee J, Choi Y, Shin E. Ribavirin Does Not Impair the Suppressive Activity of Foxp3(+)CD4(+)CD25(+) Regulatory T Cells. Immune Netw. 2013;13:25-9 pubmed publisher
Himmel M, Macdonald K, Garcia R, Steiner T, Levings M. Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans. J Immunol. 2013;190:2001-8 pubmed publisher
Trabanelli S, Ocadlikova D, Gulinelli S, Curti A, Salvestrini V, Vieira R, et al. Extracellular ATP exerts opposite effects on activated and regulatory CD4+ T cells via purinergic P2 receptor activation. J Immunol. 2012;189:1303-10 pubmed publisher
Murdoch D, Staats J, Weinhold K. OMIP-006: phenotypic subset analysis of human T regulatory cells via polychromatic flow cytometry. Cytometry A. 2012;81:281-3 pubmed publisher
Green A, Mattila J, Bigbee C, Bongers K, Lin P, Flynn J. CD4(+) regulatory T cells in a cynomolgus macaque model of Mycobacterium tuberculosis infection. J Infect Dis. 2010;202:533-41 pubmed publisher
Ndhlovu L, Leal F, Eccles James I, Jha A, Lanteri M, Norris P, et al. A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties. Eur J Immunol. 2010;40:134-41 pubmed publisher
Lyck L, Dalmau I, Chemnitz J, Finsen B, Schrøder H. Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex. J Histochem Cytochem. 2008;56:201-21 pubmed
Borsellino G, Kleinewietfeld M, Di Mitri D, Sternjak A, Diamantini A, Giometto R, et al. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood. 2007;110:1225-32 pubmed
Stockl J, Majdic O, Fischer G, Maurer D, Knapp W. Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL. J Immunol. 2001;167:2724-33 pubmed
Aversa G, Suranyi M, Waugh J, Bishop A, Hall B. Detection of a late lymphocyte activation marker by A1, a new monoclonal antibody. Transplant Proc. 1988;20:49-52 pubmed
Aversa G, Waugh J, Bishop G, Hall B. Use of monoclonal antibodies to study in vivo and in vitro-activated lymphocytes. Transplant Proc. 1989;21:349-50 pubmed
product information
Product Type :
Antibody
Product Name :
CD39 Monoclonal Antibody (eBioA1 (A1)), eBioscience
Catalog # :
14-0399-82
Quantity :
100 ug
Price :
US 278.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 0.25 ug/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1 ug/mL, Western Blot: 1 ug/mL
Species :
Human, Mouse
Clone :
eBioA1 (A1)
Isotype :
IgG1, kappa
Storage :
4 C
Description :
CD39 cell surface antigen is a 70-100kD molecule expressed on peripheral blood B cells, monocytes, T cell clones, and also weakly expressed on granulocytes. CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1 ug/mL, Western Blot: 1 ug/mL
Aliases :
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA