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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD29 (Integrin beta 1) Monoclonal Antibody (TS2/16), eBioscience™
catalog :
14-0299-82
quantity :
100µg
price :
US 128
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TS2/16
reactivity :
human, domestic sheep
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
Invitrogen product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • flow cytometry; domestic sheep; loading ...; fig 2b
Hunka J, Riley J, Debes G. Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species. BMC Vet Res. 2020;16:83 pubmed publisher
  • flow cytometry; human; fig 3a
Sakai Takemura F, Narita A, Masuda S, Wakamatsu T, Watanabe N, Nishiyama T, et al. Premyogenic progenitors derived from human pluripotent stem cells expand in floating culture and differentiate into transplantable myogenic progenitors. Sci Rep. 2018;8:6555 pubmed publisher
  • flow cytometry; human; fig 5
Sugahara K, Braun G, de Mendoza T, Kotamraju V, French R, Lowy A, et al. Tumor-penetrating iRGD peptide inhibits metastasis. Mol Cancer Ther. 2015;14:120-8 pubmed publisher
Myllymäki S, Kämäräinen U, Liu X, Cruz S, Miettinen S, Vuorela M, et al. Assembly of the β4-Integrin Interactome Based on Proximal Biotinylation in the Presence and Absence of Heterodimerization. Mol Cell Proteomics. 2019;18:277-293 pubmed publisher
Yoon D, Yoon D, Sim H, Hwang I, Lee J, Chun W. Accelerated Wound Healing by Fibroblasts Differentiated from Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells in a Pressure Ulcer Animal Model. Stem Cells Int. 2018;2018:4789568 pubmed publisher
Machado Pineda Y, Cardeñes B, Reyes R, López Martín S, Toribio V, Sánchez Organero P, et al. CD9 Controls Integrin α5β1-Mediated Cell Adhesion by Modulating Its Association With the Metalloproteinase ADAM17. Front Immunol. 2018;9:2474 pubmed publisher
Alejo A, Matamoros T, Guerra M, Andres G. A Proteomic Atlas of the African Swine Fever Virus Particle. J Virol. 2018;92: pubmed publisher
Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, et al. IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling. elife. 2018;7: pubmed publisher
Mattila J, Beaino W, Maiello P, Coleman M, White A, Scanga C, et al. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin ?4?1-Expressing Immune Cells. J Immunol. 2017;199:806-815 pubmed publisher
Starchenko A, Graves Deal R, Yang Y, Li C, Zent R, Singh B, et al. Clustering of integrin α5 at the lateral membrane restores epithelial polarity in invasive colorectal cancer cells. Mol Biol Cell. 2017;28:1288-1300 pubmed publisher
Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, et al. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries. Nat Commun. 2017;8:14797 pubmed publisher
Zhou F, Gao S, Wang L, Sun C, Chen L, Yuan P, et al. Human adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery occlusion model. Stem Cell Res Ther. 2015;6:92 pubmed publisher
Yuan S, Guo Y, Zhou X, Shen W, Chen H. PDGFR-? (+) perivascular cells from infantile hemangioma display the features of mesenchymal stem cells and show stronger adipogenic potential in vitro and in vivo. Int J Clin Exp Pathol. 2014;7:2861-70 pubmed
Michishita M, Ezaki S, Ogihara K, Naya Y, Azakami D, Nakagawa T, et al. Identification of tumor-initiating cells in a canine hepatocellular carcinoma cell line. Res Vet Sci. 2014;96:315-22 pubmed publisher
Rankin C, Hilgarth R, Leoni G, Kwon M, Den Beste K, Parkos C, et al. Annexin A2 regulates ?1 integrin internalization and intestinal epithelial cell migration. J Biol Chem. 2013;288:15229-39 pubmed publisher
Beaty B, Sharma V, Bravo Cordero J, Simpson M, Eddy R, Koleske A, et al. ?1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell. 2013;24:1661-75, S1-11 pubmed publisher
Chou J, Lin J, Brenot A, Kim J, Provot S, Werb Z. GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol. 2013;15:201-13 pubmed publisher
Fekete N, Rojewski M, Furst D, Kreja L, Ignatius A, Dausend J, et al. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS ONE. 2012;7:e43255 pubmed publisher
Weber C, Alon R, Moser B, Springer T. Sequential regulation of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis. J Cell Biol. 1996;134:1063-73 pubmed
Hemler M, Sanchez Madrid F, Flotte T, Krensky A, Burakoff S, Bhan A, et al. Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. J Immunol. 1984;132:3011-8 pubmed
product information
Product Type :
Antibody
Product Name :
CD29 (Integrin beta 1) Monoclonal Antibody (TS2/16), eBioscience™
Catalog # :
14-0299-82
Quantity :
100µg
Price :
US 128
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1000
Species :
Human
Clone :
TS2/16
Isotype :
IgG1, kappa
Storage :
4° C
Description :
ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins. ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug. ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue. Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease. Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta. More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. The distribution pattern in adult tissues for integrin beta types are mutually exclusive. Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1000
Aliases :
4633401G24Rik; AA409975; AA960159; Beta OL; Beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; GPIIA; integrin beta 1; integrin beta 1 (fibronectin receptor beta); Integrin beta1; Integrin beta-1; integrin beta-1 subunit; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA