CD29 (Integrin beta 1) Monoclonal Antibody (TS2/16), eBioscience | Invitrogen 14-0299-37 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD29 (Integrin beta 1) Monoclonal Antibody (TS2/16), eBioscience

catalog :

14-0299-37

quantity :

2 mg

price :

US 1392.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TS2/16

reactivity :

human, domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
flow cytometry; domestic sheep; loading ...; fig 2b	Hunka J, Riley J, Debes G. Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species. BMC Vet Res. 2020;16:83 pubmed publisher
	Li W, Lou X, Zha Y, Qin Y, Zha J, Hong L, et al. Single-cell RNA-seq of heart reveals intercellular communication drivers of myocardial fibrosis in diabetic cardiomyopathy. elife. 2023;12: pubmed publisher
	Chen X, Zhong W, Chang Y, Song T, Liu B, Kong X, et al. Comparative proteomic analysis of the mitochondria of menstrual stem cells and ovarian cancer cells. Exp Ther Med. 2023;25:99 pubmed publisher
	McCurdy S, Lin J, Shenkar R, Moore T, Lightle R, Faurobert E, et al. β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations. FASEB J. 2022;36:e22629 pubmed publisher
	Liu Y, Zhang X, Hu Y, Kang M, Wu Y, Wang Y, et al. Human placental mesenchymal stem cells regulate inflammation via the NF‑κB signaling pathway. Exp Ther Med. 2022;24:654 pubmed publisher
	Mu R, Chen B, Bi B, Yu H, Liu J, Li J, et al. LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling. Int J Med Sci. 2022;19:1307-1319 pubmed publisher
	Danielsson B, Tieu K, Spagnol S, Vu K, Cabe J, Raisch T, et al. Chromatin condensation regulates endothelial cell adaptation to shear stress. Mol Biol Cell. 2022;33:ar101 pubmed publisher
	Deissler H, Busch C, Wolf A, Rehak M. Beovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in vitro. Sci Rep. 2022;12:12493 pubmed publisher
	Deissler H, Rehak M, Wolf A. Impairment of the Retinal Endothelial Cell Barrier Induced by Long-Term Treatment with VEGF-A165 No Longer Depends on the Growth Factor's Presence. Biomolecules. 2022;12: pubmed publisher
	Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, et al. Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression. J Exp Clin Cancer Res. 2021;40:214 pubmed publisher
	Wu Y, Huang Y, Zhang W, Gunst S. The proprotein convertase furin inhibits IL-13-induced inflammation in airway smooth muscle by regulating integrin-associated signaling complexes. Am J Physiol Lung Cell Mol Physiol. 2021;321:L102-L115 pubmed publisher
	Deng C, Hu C, Ling S, Zhao N, Bao L, Zhou F, et al. Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration. Cell Death Differ. 2021;28:1041-1061 pubmed publisher
	Liu J, Qiu X, Lv Y, Zheng C, Dong Y, Dou G, et al. Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages. Stem Cell Res Ther. 2020;11:507 pubmed publisher
	Yu C, Chen P, Xu J, Liu Y, Li H, Wang L, et al. hADSCs derived extracellular vesicles inhibit NLRP3inflammasome activation and dry eye. Sci Rep. 2020;10:14521 pubmed publisher
	Sierra Parraga J, Merino A, Eijken M, Leuvenink H, Ploeg R, Møller B, et al. Reparative effect of mesenchymal stromal cells on endothelial cells after hypoxic and inflammatory injury. Stem Cell Res Ther. 2020;11:352 pubmed publisher
	Jäckle A, Ziemssen F, Kuhn E, Kampmeier J, Lang G, Lang G, et al. Sitagliptin and the Blood-Retina Barrier: Effects on Retinal Endothelial Cells Manifested Only after Prolonged Exposure. J Diabetes Res. 2020;2020:2450781 pubmed publisher
	Kwon J, Vankara A, Ettyreddy A, Bohning J, Gersbach C. Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators. Stem Cell Reports. 2020;14:755-769 pubmed publisher
	Yoon D, Yoon D, Sim H, Hwang I, Lee J, Chun W. Accelerated Wound Healing by Fibroblasts Differentiated from Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells in a Pressure Ulcer Animal Model. Stem Cells Int. 2018;2018:4789568 pubmed publisher
	Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, et al. IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling. elife. 2018;7: pubmed publisher
	Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, et al. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries. Nat Commun. 2017;8:14797 pubmed publisher
	Zhou F, Gao S, Wang L, Sun C, Chen L, Yuan P, et al. Human adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery occlusion model. Stem Cell Res Ther. 2015;6:92 pubmed publisher
	Sugahara K, Braun G, de Mendoza T, Kotamraju V, French R, Lowy A, et al. Tumor-penetrating iRGD peptide inhibits metastasis. Mol Cancer Ther. 2015;14:120-8 pubmed publisher
	Yuan S, Guo Y, Zhou X, Shen W, Chen H. PDGFR-? (+) perivascular cells from infantile hemangioma display the features of mesenchymal stem cells and show stronger adipogenic potential in vitro and in vivo. Int J Clin Exp Pathol. 2014;7:2861-70 pubmed
	Rankin C, Hilgarth R, Leoni G, Kwon M, Den Beste K, Parkos C, et al. Annexin A2 regulates ?1 integrin internalization and intestinal epithelial cell migration. J Biol Chem. 2013;288:15229-39 pubmed publisher
	Chou J, Lin J, Brenot A, Kim J, Provot S, Werb Z. GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol. 2013;15:201-13 pubmed publisher
	Fekete N, Rojewski M, Furst D, Kreja L, Ignatius A, Dausend J, et al. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS ONE. 2012;7:e43255 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD29 (Integrin beta 1) Monoclonal Antibody (TS2/16), eBioscience

Catalog # :

14-0299-37

Quantity :

2 mg

Price :

US 1392.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1,000

Species :

Human

Clone :

TS2/16

Isotype :

IgG1, kappa

Storage :

4° C

Description :

ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins. ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug. ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue. Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease. Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta. More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. The distribution pattern in adult tissues for integrin beta types are mutually exclusive. Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1,000

Aliases :

4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA

more info or order :

Invitrogen product webpage