| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; human; fig 2e
| Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1d
| Xing S, Gai K, Li X, Shao P, Zeng Z, Zhao X, et al. Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells. J Exp Med. 2019;: pubmed publisher |
- flow cytometry; human; loading ...; fig 6a
| Muscate F, Stetter N, Schramm C, Schulze zur Wiesch J, Bosurgi L, Jacobs T. HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage. Front Immunol. 2018;9:2611 pubmed publisher |
- blocking or activating experiments; mouse; 3 ug/ml; fig 2
| Swamy M, Pathak S, Grzes K, Damerow S, Sinclair L, van Aalten D, et al. Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy. Nat Immunol. 2016;17:712-20 pubmed publisher |
- blocking or activating experiments; mouse; fig 4
| Kabat A, Harrison O, Riffelmacher T, Moghaddam A, Pearson C, Laing A, et al. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. elife. 2016;5:e12444 pubmed publisher |
- blocking or activating experiments; mouse; fig 4
| Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher |
- flow cytometry; mouse; fig 2
| Verma S, Weiskopf D, Gupta A, McDonald B, Peters B, Sette A, et al. Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection. J Virol. 2016;90:650-8 pubmed publisher |
- blocking or activating experiments; mouse; fig 1f
- flow cytometry; mouse; 1 ug/ml; fig 1b
| Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, et al. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol. 2015;16:1077-84 pubmed publisher |
- blocking or activating experiments; mouse; 1:500
| Pearce V, Bouabe H, MacQueen A, Carbonaro V, Okkenhaug K. PI3Kδ Regulates the Magnitude of CD8+ T Cell Responses after Challenge with Listeria monocytogenes. J Immunol. 2015;195:3206-17 pubmed publisher |
- blocking or activating experiments; mouse
| Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed publisher |
- flow cytometry; mouse; fig 1
| Buchwald Z, Yang C, Nellore S, Shashkova E, Davis J, Cline A, et al. A Bone Anabolic Effect of RANKL in a Murine Model of Osteoporosis Mediated Through FoxP3+ CD8 T Cells. J Bone Miner Res. 2015;30:1508-22 pubmed publisher |
- blocking or activating experiments; mouse; 2 ug/ml
| Sakaguchi S, Hombauer M, Hassan H, Tanaka H, Yasmin N, Naoe Y, et al. A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells. J Leukoc Biol. 2015;97:635-44 pubmed publisher |
- blocking or activating experiments; mouse; 5 ug/ml
- flow cytometry; mouse; 5 ug/ml
| Arndt B, Witkowski L, Ellwart J, Seissler J. CD8+ CD122+ PD-1- effector cells promote the development of diabetes in NOD mice. J Leukoc Biol. 2015;97:111-20 pubmed publisher |
- blocking or activating experiments; mouse; fig 1e
| Backer R, Helbig C, Gentek R, Kent A, Laidlaw B, Dominguez C, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nat Immunol. 2014;15:1143-51 pubmed publisher |
- blocking or activating experiments; mouse
| Bashour K, Gondarenko A, Chen H, Shen K, Liu X, Huse M, et al. CD28 and CD3 have complementary roles in T-cell traction forces. Proc Natl Acad Sci U S A. 2014;111:2241-6 pubmed publisher |
- blocking or activating experiments; mouse
| Yang C, Li J, Chiu L, Lan J, Chen D, Chuang H, et al. Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation. J Immunol. 2014;192:1547-57 pubmed publisher |
- flow cytometry; mouse; 2 ug/ml
| Hu Y, Xiao H, Shi T, Oppenheim J, Chen X. Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4? Foxp3? regulatory T cells. Immunology. 2014;142:193-201 pubmed publisher |
- flow cytometry; mouse; fig 4
| Salinas N, Olguín J, Castellanos C, Saavedra R. T cell suppression in vitro during Toxoplasma gondii infection is the result of IL-2 competition between Tregs and T cells leading to death of proliferating T cells. Scand J Immunol. 2014;79:1-11 pubmed publisher |
- blocking or activating experiments; mouse; 200 ng/ml
| Sheng H, Wang Y, Jin Y, Zhang Q, Zhang Y, Wang L, et al. A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res. 2008;18:846-57 pubmed publisher |
- flow cytometry; mouse; fig 1
| Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed |
- flow cytometry; mouse; 10 ug/ml; fig 2
| Krieg C, Han P, Stone R, Goularte O, Kaye J. Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells. J Immunol. 2005;175:6420-7 pubmed |
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| Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher |
| Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher |
| Bending D, Paduraru A, Ducker C, Prieto Martin P, Crompton T, Ono M. A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme. EMBO J. 2018;37: pubmed publisher |
| Sinclair L, Neyens D, Ramsay G, Taylor P, Cantrell D. Single cell analysis of kynurenine and System L amino acid transport in T cells. Nat Commun. 2018;9:1981 pubmed publisher |
| Zhang J, Qiu X, Zhang N, Tang W, Gober H, Li D, et al. Bu‑Shen‑Ning‑Xin decoction suppresses osteoclastogenesis by modulating RANKL/OPG imbalance in the CD4+ T lymphocytes of ovariectomized mice. Int J Mol Med. 2018;42:299-308 pubmed publisher |
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| Moreno Fernandez M, Giles D, Stankiewicz T, Sheridan R, Karns R, Cappelletti M, et al. Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease. JCI Insight. 2018;3: pubmed publisher |
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| Mencarelli A, Vacca M, Khameneh H, Acerbi E, Tay A, Zolezzi F, et al. Calcineurin B in CD4+ T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway. Front Immunol. 2018;9:261 pubmed publisher |
| Zhao M, Tan Y, Peng Q, Huang C, Guo Y, Liang G, et al. IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation. Nat Commun. 2018;9:583 pubmed publisher |
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| Villadiego J, Labrador Garrido A, Franco J, Leal Lasarte M, De Genst E, Dobson C, et al. Immunization with ?-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model. Glia. 2018;66:191-205 pubmed publisher |
| Hope J, Stairiker C, Spantidea P, Gracias D, Carey A, Fike A, et al. The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1. Front Immunol. 2017;8:1696 pubmed publisher |
| Kumar P, Kolls J. Lymphocyte Isolation, Th17 Cell Differentiation, Activation, and Staining. Bio Protoc. 2016;6: pubmed publisher |
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| Ciarlo E, Heinonen T, Théroude C, Herderschee J, Mombelli M, Lugrin J, et al. Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection. Front Immunol. 2017;8:1037 pubmed publisher |
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| Jang E, Lee H, Lee G, Oh A, Cha J, Igarashi K, et al. Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4＋ T cells. BMB Rep. 2017;50:472-477 pubmed |
| He Z, Ma J, Wang R, Zhang J, Huang Z, Wang F, et al. A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development. Nat Immunol. 2017;18:1128-1138 pubmed publisher |
| Hosokawa T, Kimura T, Nada S, Okuno T, Ito D, Kang S, et al. Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function. J Immunol. 2017;199:2008-2019 pubmed publisher |
| Van Den Ham K, Smith L, Richer M, Olivier M. Protein Tyrosine Phosphatase Inhibition Prevents Experimental Cerebral Malaria by Precluding CXCR3 Expression on T Cells. Sci Rep. 2017;7:5478 pubmed publisher |
| Chen J, Martindale J, Cramer C, Gorospe M, Atasoy U, Drew P, et al. The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells. J Biol Chem. 2017;292:14532-14543 pubmed publisher |
| Mancera P, Wappenhans B, Cordobilla B, Virgili N, Pugliese M, Rueda F, et al. Natural Docosahexaenoic Acid in the Triglyceride Form Attenuates In Vitro Microglial Activation and Ameliorates Autoimmune Encephalomyelitis in Mice. Nutrients. 2017;9: pubmed publisher |
| Moffett H, Cartwright A, Kim H, Godec J, Pyrdol J, Aijö T, et al. The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection. Nat Immunol. 2017;18:791-799 pubmed publisher |
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| Dombrowski Y, O Hagan T, Dittmer M, Penalva R, Mayoral S, Bankhead P, et al. Regulatory T cells promote myelin regeneration in the central nervous system. Nat Neurosci. 2017;20:674-680 pubmed publisher |
| Prados Rosales R, Carreño L, Cheng T, Blanc C, Weinrick B, Malek A, et al. Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine. PLoS Pathog. 2017;13:e1006250 pubmed publisher |
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| Blanquiceth Y, Rodríguez Perea A, Tabares Guevara J, Correa L, Sánchez M, Ramirez Pineda J, et al. Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma. Front Immunol. 2016;7:620 pubmed publisher |
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| Song M, Nair V, Oh K. Vitamin C enhances the expression of IL17 in a Jmjd2-dependent manner. BMB Rep. 2017;50:49-54 pubmed |
| Davis R, Silvin C, Allen C. Avoiding phagocytosis-related artifact in myeloid derived suppressor cell T-lymphocyte suppression assays. J Immunol Methods. 2017;440:12-18 pubmed publisher |
| Gomes R, Cavalcanti K, Teixeira C, Carvalho A, Mattos P, Cristal J, et al. Immunity to Lutzomyia whitmani Saliva Protects against Experimental Leishmania braziliensis Infection. PLoS Negl Trop Dis. 2016;10:e0005078 pubmed publisher |
| Massaad M, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, et al. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. J Clin Invest. 2016;126:4219-4236 pubmed publisher |
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| Eil R, Vodnala S, Clever D, Klebanoff C, Sukumar M, Pan J, et al. Ionic immune suppression within the tumour microenvironment limits T cell effector function. Nature. 2016;537:539-543 pubmed publisher |
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| Holmgaard R, Zamarin D, Lesokhin A, Merghoub T, Wolchok J. Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors. EBioMedicine. 2016;6:50-58 pubmed publisher |
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