CD23 Monoclonal Antibody (EBVCS2), eBioscience™ | Invitrogen 14-0238-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD23 Monoclonal Antibody (EBVCS2), eBioscience™

catalog :

14-0238-82

quantity :

100µg

price :

US 117

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

EBVCS2

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; tbl 4	Fromm J, Tagliente D, Shaver A, Neppalli V, Craig F. Case study interpretation: Report from the ICCS Annual Meeting, Seattle, 2014. Cytometry B Clin Cytom. 2015;88:413-24 pubmed publisher
flow cytometry; human	Barbosa R, Silva S, Silva S, Melo A, Pereira Santos M, Barata J, et al. Reduced BAFF-R and increased TACI expression in common variable immunodeficiency. J Clin Immunol. 2014;34:573-83 pubmed publisher
	Selb R, Eckl Dorna J, Twaroch T, Lupinek C, Teufelberger A, Hofer G, et al. Critical and direct involvement of the CD23 stalk region in IgE binding. J Allergy Clin Immunol. 2017;139:281-289.e5 pubmed publisher
	Os A, Burgler S, Ribes A, Funderud A, Wang D, Thompson K, et al. Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013;4:566-77 pubmed publisher
	Labuda L, Ateba Ngoa U, Feugap E, Heeringa J, van der Vlugt L, Pires R, et al. Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis. PLoS Negl Trop Dis. 2013;7:e2094 pubmed publisher
	Pupovac A, Foster C, Sluyter R. Human P2X7 receptor activation induces the rapid shedding of CXCL16. Biochem Biophys Res Commun. 2013;432:626-31 pubmed publisher
	Stolfi C, Caruso R, Franzè E, Sarra M, De Nitto D, Rizzo A, et al. Interleukin-25 fails to activate STAT6 and induce alternatively activated macrophages. Immunology. 2011;132:66-77 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD23 Monoclonal Antibody (EBVCS2), eBioscience™

Catalog # :

14-0238-82

Quantity :

100µg

Price :

US 117

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Frozen): Assay-Dependent

Species :

Human

Clone :

EBVCS2

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; FCE2; Fc-epsilon-RII; Fcer2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; Low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; Lymphocyte IgE receptor

more info or order :

Invitrogen product webpage