CD23 Monoclonal Antibody (B3B4), eBioscience™ | Invitrogen 14-0232-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD23 Monoclonal Antibody (B3B4), eBioscience™

catalog :

14-0232-95

quantity :

10 mg

price :

US 3000.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

B3B4

reactivity :

mouse

application :

immunohistochemistry, flow cytometry

citations: 21

Reference
Gautam A, Park B, Kim T, Akauliya M, Kim D, Maharjan S, et al. Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus. Front Immunol. 2019;10:1160 pubmed publisher
Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, et al. Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. Sci Adv. 2018;4:eaar5701 pubmed publisher
Bai W, Li C, Zhang C, Xu L, Zeng Q, Hu B, et al. Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells. Front Immunol. 2017;8:1919 pubmed publisher
Seehus C, Kadavallore A, Torre B, Yeckes A, Wang Y, Tang J, et al. Alternative activation generates IL-10 producing type 2 innate lymphoid cells. Nat Commun. 2017;8:1900 pubmed publisher
Niki M, Nakajima K, Ishikawa D, Nishida J, Ishifune C, Tsukumo S, et al. MicroRNA-449a deficiency promotes colon carcinogenesis. Sci Rep. 2017;7:10696 pubmed publisher
Huang B, Gomez Rodriguez J, Preite S, Garrett L, Harper U, Schwartzberg P. CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development. PLoS ONE. 2016;11:e0156072 pubmed publisher
Harmon D, Srikakulapu P, Kaplan J, Oldham S, McSkimming C, Garmey J, et al. Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2016;36:682-91 pubmed publisher
Almaden J, Liu Y, Yang E, Otero D, Birnbaum H, Davis Turak J, et al. B-cell survival and development controlled by the coordination of NF-ÎºB family members RelB and cRel. Blood. 2016;127:1276-86 pubmed publisher
Sindhava V, Scholz J, Stohl W, Cancro M. APRIL mediates peritoneal B-1 cell homeostasis. Immunol Lett. 2014;160:120-7 pubmed publisher
Kirchenbaum G, St Clair J, Detanico T, Aviszus K, Wysocki L. Functionally responsive self-reactive B cells of low affinity express reduced levels of surface IgM. Eur J Immunol. 2014;44:970-82 pubmed publisher
Katz S, LaBelle J, Meng H, Valeriano R, Fisher J, Sun H, et al. Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells. Blood. 2014;123:884-93 pubmed publisher
Mollo S, Zajac A, Harrington L. Temporal requirements for B cells in the establishment of CD4 T cell memory. J Immunol. 2013;191:6052-9 pubmed publisher
Detre C, Yigit B, Keszei M, Castro W, Magelky E, Terhorst C. SAP modulates B cell functions in a genetic background-dependent manner. Immunol Lett. 2013;153:15-21 pubmed publisher
Jordan S, Ruzsics Z, MitroviÄ‡ M, Baranek T, ArapoviÄ‡ J, KrmpotiÄ‡ A, et al. Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection. Cell Host Microbe. 2013;13:535-545 pubmed publisher
Andrews S, Zhang Q, Lim S, Li L, Lee J, Zheng N, et al. Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity. J Exp Med. 2013;210:125-42 pubmed publisher
Yu M, Chen Y, He Y, Podd A, Fu G, Wright J, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-?B activation and survival of anergic B cells. J Immunol. 2012;189:5185-93 pubmed publisher
Debnath I, Roundy K, Pioli P, Weis J, Weis J. Bone marrow-induced Mef2c deficiency delays B-cell development and alters the expression of key B-cell regulatory proteins. Int Immunol. 2013;25:99-115 pubmed publisher
Srinivasan L, Sasaki Y, Calado D, Zhang B, Paik J, Depinho R, et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell. 2009;139:573-86 pubmed publisher
Chevrier S, Genton C, Kallies A, Karnowski A, Otten L, Malissen B, et al. CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche. Proc Natl Acad Sci U S A. 2009;106:3895-900 pubmed publisher
Schuman J, Chen Y, Podd A, Yu M, Liu H, Wen R, et al. A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation. Blood. 2009;113:4566-74 pubmed publisher
Wang C, McDonald K, McDonough J, Newberry R. Murine isolated lymphoid follicles contain follicular B lymphocytes with a mucosal phenotype. Am J Physiol Gastrointest Liver Physiol. 2006;291:G595-604 pubmed

product information

Product Type :

Antibody

Product Name :

CD23 Monoclonal Antibody (B3B4), eBioscience™

Catalog # :

14-0232-95

Quantity :

10 mg

Price :

US 3000.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test, Immunohistochemistry: Assay-Dependent

Species :

Mouse

Clone :

B3B4

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Immunohistochemistry: Assay-Dependent

Aliases :

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; FCE2; Fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; Lymphocyte IgE receptor