product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD23 Monoclonal Antibody (B3B4), eBioscience™
catalog :
14-0232-81
quantity :
50µg
price :
US 63.5
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
B3B4
reactivity :
mouse
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 122
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig e10
Majer O, Liu B, Kreuk L, Krogan N, Barton G. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity. Nature. 2019;575:366-370 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s9b
Zhao X, Xie H, Zhao M, Ahsan A, Li X, Wang F, et al. Fc receptor-like 1 intrinsically recruits c-Abl to enhance B cell activation and function. Sci Adv. 2019;5:eaaw0315 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Imbrechts M, De Samblancx K, Fierens K, Brisse E, Vandenhaute J, Mitera T, et al. IFN-γ stimulates CpG-induced IL-10 production in B cells via p38 and JNK signalling pathways. Eur J Immunol. 2018;48:1506-1521 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Yao Y, Huang W, Li X, Li X, Qian J, Han H, et al. Tespa1 Deficiency Dampens Thymus-Dependent B-Cell Activation and Attenuates Collagen-Induced Arthritis in Mice. Front Immunol. 2018;9:965 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s4b
Yeh C, Nojima T, Kuraoka M, Kelsoe G. Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density. Nat Commun. 2018;9:928 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4a
Vo L, Kinney M, Liu X, Zhang Y, Barragan J, Sousa P, et al. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018;553:506-510 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Stengel K, Barnett K, Wang J, Liu Q, Hodges E, Hiebert S, et al. Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development. Proc Natl Acad Sci U S A. 2017;114:8608-8613 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher
  • flow cytometry; mouse; fig 1b
van der Vlugt L, Obieglo K, Ozir Fazalalikhan A, Sparwasser T, Haeberlein S, Smits H. Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function. Int J Parasitol. 2017;47:545-554 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Elgueta R, Tse D, Deharvengt S, Luciano M, CARRIERE C, Noelle R, et al. Endothelial Plasmalemma Vesicle-Associated Protein Regulates the Homeostasis of Splenic Immature B Cells and B-1 B Cells. J Immunol. 2016;197:3970-3981 pubmed
  • flow cytometry; mouse; loading ...; fig 1a
Chen S, Miyazaki M, Chandra V, Fisch K, Chang A, Murre C. Id3 Orchestrates Germinal Center B Cell Development. Mol Cell Biol. 2016;36:2543-52 pubmed publisher
  • flow cytometry; mouse; 1:100
Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
  • flow cytometry; mouse; tbl s3
Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed publisher
  • flow cytometry; mouse; fig 2
Reynolds A, Kuraoka M, Kelsoe G. Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. J Immunol. 2015;194:231-42 pubmed publisher
  • flow cytometry; mouse; fig 3
Fahl S, Harris B, Coffey F, Wiest D. Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint. J Immunol. 2015;194:200-9 pubmed
  • flow cytometry; mouse
Honjo K, Kubagawa Y, Suzuki Y, Takagi M, Ohno H, Bucy R, et al. Enhanced auto-antibody production and Mott cell formation in Fc?R-deficient autoimmune mice. Int Immunol. 2014;26:659-72 pubmed publisher
  • flow cytometry; mouse
Alsadeq A, Hobeika E, Medgyesi D, Kläsener K, Reth M. The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling. J Immunol. 2014;193:268-76 pubmed publisher
  • flow cytometry; mouse
Satpathy A, Briseño C, Lee J, Ng D, Manieri N, Kc W, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol. 2013;14:937-48 pubmed publisher
  • flow cytometry; mouse
Mathew R, Seiler M, Scanlon S, Mao A, Constantinides M, Bertozzi Villa C, et al. BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature. 2012;491:618-21 pubmed publisher
Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, et al. Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. Sci Adv. 2018;4:eaar5701 pubmed publisher
Bai W, Li C, Zhang C, Xu L, Zeng Q, Hu B, et al. Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells. Front Immunol. 2017;8:1919 pubmed publisher
Seehus C, Kadavallore A, Torre B, Yeckes A, Wang Y, Tang J, et al. Alternative activation generates IL-10 producing type 2 innate lymphoid cells. Nat Commun. 2017;8:1900 pubmed publisher
Niki M, Nakajima K, Ishikawa D, Nishida J, Ishifune C, Tsukumo S, et al. MicroRNA-449a deficiency promotes colon carcinogenesis. Sci Rep. 2017;7:10696 pubmed publisher
Vaidyanathan B, Chaudhry A, Yewdell W, Angeletti D, Yen W, Wheatley A, et al. The aryl hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med. 2017;214:197-208 pubmed publisher
Huang B, Gomez Rodriguez J, Preite S, Garrett L, Harper U, Schwartzberg P. CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development. PLoS ONE. 2016;11:e0156072 pubmed publisher
Harmon D, Srikakulapu P, Kaplan J, Oldham S, McSkimming C, Garmey J, et al. Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2016;36:682-91 pubmed publisher
Almaden J, Liu Y, Yang E, Otero D, Birnbaum H, Davis Turak J, et al. B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel. Blood. 2016;127:1276-86 pubmed publisher
Sindhava V, Scholz J, Stohl W, Cancro M. APRIL mediates peritoneal B-1 cell homeostasis. Immunol Lett. 2014;160:120-7 pubmed publisher
Azcárate I, Marín García P, Kamali A, Pérez Benavente S, Puyet A, Diez A, et al. Differential immune response associated to malaria outcome is detectable in peripheral blood following Plasmodium yoelii infection in mice. PLoS ONE. 2014;9:e85664 pubmed publisher
Racine J, Wang M, Zhang M, Zeng D. Induction of mixed chimerism depletes pre-existing and de novo-developed autoreactive B cells in autoimmune NOD mice. Diabetes. 2014;63:2051-62 pubmed publisher
Peterson L, Pennington L, Shaw L, Brown M, Treacy E, Friend S, et al. SLAP deficiency decreases dsDNA autoantibody production. Clin Immunol. 2014;150:201-9 pubmed publisher
Kallberg E, Ivars F, Leanderson T. Quinoline-3-carboxamides modulate primary T cell-dependent B cell responses but do not inhibit functional immunity. Scand J Immunol. 2014;79:237-43 pubmed publisher
Kirchenbaum G, St Clair J, Detanico T, Aviszus K, Wysocki L. Functionally responsive self-reactive B cells of low affinity express reduced levels of surface IgM. Eur J Immunol. 2014;44:970-82 pubmed publisher
Katz S, LaBelle J, Meng H, Valeriano R, Fisher J, Sun H, et al. Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells. Blood. 2014;123:884-93 pubmed publisher
Mollo S, Zajac A, Harrington L. Temporal requirements for B cells in the establishment of CD4 T cell memory. J Immunol. 2013;191:6052-9 pubmed publisher
Donius L, Weis J. Detection of complement receptors 1 and 2 on mouse splenic B cells using flow cytometry. Methods Mol Biol. 2014;1100:305-10 pubmed publisher
Caganova M, Carrisi C, Varano G, Mainoldi F, Zanardi F, Germain P, et al. Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis. J Clin Invest. 2013;123:5009-22 pubmed publisher
Boulianne B, Le M, Ward L, Meng L, Haddad D, Li C, et al. AID-expressing germinal center B cells cluster normally within lymph node follicles in the absence of FDC-M1+ CD35+ follicular dendritic cells but dissipate prematurely. J Immunol. 2013;191:4521-30 pubmed publisher
Bartlett A, Buhlmann J, Stone J, Lim B, Barrington R. Multiple checkpoint breach of B cell tolerance in Rasgrp1-deficient mice. J Immunol. 2013;191:3605-13 pubmed publisher
Yau I, Cato M, Jellusova J, Hurtado de Mendoza T, Brink R, Rickert R. Censoring of self-reactive B cells by follicular dendritic cell-displayed self-antigen. J Immunol. 2013;191:1082-90 pubmed publisher
Ito C, Yamazaki H, Yamane T. Earliest hematopoietic progenitors at embryonic day 9 preferentially generate B-1 B cells rather than follicular B or marginal zone B cells. Biochem Biophys Res Commun. 2013;437:307-13 pubmed publisher
Detre C, Yigit B, Keszei M, Castro W, Magelky E, Terhorst C. SAP modulates B cell functions in a genetic background-dependent manner. Immunol Lett. 2013;153:15-21 pubmed publisher
Stolp J, Marino E, Batten M, Sierro F, Cox S, Grey S, et al. Intrinsic molecular factors cause aberrant expansion of the splenic marginal zone B cell population in nonobese diabetic mice. J Immunol. 2013;191:97-109 pubmed publisher
Donius L, Handy J, Weis J, Weis J. Optimal germinal center B cell activation and T-dependent antibody responses require expression of the mouse complement receptor Cr1. J Immunol. 2013;191:434-47 pubmed publisher
Jordan S, Ruzsics Z, Mitrović M, Baranek T, Arapović J, Krmpotić A, et al. Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection. Cell Host Microbe. 2013;13:535-545 pubmed publisher
Ren W, Lagerstedt K, Grimsholm O, Stern A, Sun J, Fang Y, et al. Uncoupling of natural IgE production and CD23 surface expression levels. PLoS ONE. 2013;8:e62851 pubmed publisher
Andrews S, Zhang Q, Lim S, Li L, Lee J, Zheng N, et al. Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity. J Exp Med. 2013;210:125-42 pubmed publisher
Yu M, Chen Y, He Y, Podd A, Fu G, Wright J, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-?B activation and survival of anergic B cells. J Immunol. 2012;189:5185-93 pubmed publisher
Debnath I, Roundy K, Pioli P, Weis J, Weis J. Bone marrow-induced Mef2c deficiency delays B-cell development and alters the expression of key B-cell regulatory proteins. Int Immunol. 2013;25:99-115 pubmed publisher
Ramon S, Bancos S, Thatcher T, Murant T, Moshkani S, Sahler J, et al. Peroxisome proliferator-activated receptor ? B cell-specific-deficient mice have an impaired antibody response. J Immunol. 2012;189:4740-7 pubmed publisher
Szczepanek S, McNamara J, Secor E, Natarajan P, Guernsey L, Miller L, et al. Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease. Am J Pathol. 2012;181:1725-34 pubmed publisher
Wöhner M, Born S, Nitschke L. Human CD22 cannot fully substitute murine CD22 functions in vivo, as shown in a new knockin mouse model. Eur J Immunol. 2012;42:3009-18 pubmed publisher
Biswas P, Kang K, Gupta S, Bhagat G, Pernis A. A murine autoimmune model of rheumatoid arthritis and systemic lupus erythematosus associated with deregulated production of IL-17 and IL-21. Methods Mol Biol. 2012;900:233-51 pubmed publisher
Nijnik A, Clare S, Hale C, Chen J, Raisen C, Mottram L, et al. The role of sphingosine-1-phosphate transporter Spns2 in immune system function. J Immunol. 2012;189:102-11 pubmed publisher
Moshkani S, Kuzin I, Adewale F, Jansson J, Sanz I, Schwarz E, et al. CD23+ CD21(high) CD1d(high) B cells in inflamed lymph nodes are a locally differentiated population with increased antigen capture and activation potential. J Immunol. 2012;188:5944-53 pubmed publisher
Kaneko T, Saito Y, Kotani T, Okazawa H, Iwamura H, Sato Hashimoto M, et al. Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity. J Immunol. 2012;188:5397-407 pubmed publisher
Galbas T, Steimle V, Lapointe R, Ishido S, Thibodeau J. MARCH1 down-regulation in IL-10-activated B cells increases MHC class II expression. Cytokine. 2012;59:27-30 pubmed publisher
Bankoti R, Gupta K, Levchenko A, Stager S. Marginal zone B cells regulate antigen-specific T cell responses during infection. J Immunol. 2012;188:3961-71 pubmed publisher
van der Vlugt L, Labuda L, Ozir Fazalalikhan A, Lievers E, Gloudemans A, Liu K, et al. Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells. PLoS ONE. 2012;7:e30883 pubmed publisher
Iseki M, Omori Miyake M, Xu W, Sun X, Takaki S, Rawlings D, et al. Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4. Int Immunol. 2012;24:183-95 pubmed publisher
Siggs O, Li X, Xia Y, Beutler B. ZBTB1 is a determinant of lymphoid development. J Exp Med. 2012;209:19-27 pubmed publisher
Maseda D, Smith S, DiLillo D, Bryant J, Candando K, Weaver C, et al. Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. J Immunol. 2012;188:1036-48 pubmed publisher
Shen S, Manser T. Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing. J Immunol. 2012;188:47-56 pubmed publisher
Vu T, Gatto D, Turner V, Funnell A, Mak K, Norton L, et al. Impaired B cell development in the absence of Krüppel-like factor 3. J Immunol. 2011;187:5032-42 pubmed publisher
Chaplin J, Kasahara S, Clark E, Ledbetter J. Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway. J Immunol. 2011;187:4199-209 pubmed publisher
Nikbakht N, Migone T, Ward C, Manser T. Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments. J Immunol. 2011;187:37-46 pubmed publisher
Billiard F, Kirshner J, Tait M, Danave A, Taheri S, Zhang W, et al. Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus. Eur J Immunol. 2011;41:2207-16 pubmed publisher
Hams E, McCarron M, Amu S, Yagita H, Azuma M, Chen L, et al. Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells. J Immunol. 2011;186:5648-55 pubmed publisher
Ackermann J, Radtke D, Maurberger A, Winkler T, Nitschke L. Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling. EMBO J. 2011;30:1621-33 pubmed publisher
Ota T, Ota M, Duong B, Gavin A, Nemazee D. Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing. J Exp Med. 2011;208:617-29 pubmed publisher
Birjandi S, Ippolito J, Ramadorai A, Witte P. Alterations in marginal zone macrophages and marginal zone B cells in old mice. J Immunol. 2011;186:3441-51 pubmed publisher
Cox S, Stolp J, Hallahan N, Counotte J, Zhang W, Serreze D, et al. Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a ?-cell neo-self-antigen in type 1 diabetes prone NOD mice. Eur J Immunol. 2010;40:3413-25 pubmed publisher
DeKoter R, Geadah M, Khoosal S, Xu L, Thillainadesan G, Torchia J, et al. Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C. J Immunol. 2010;185:7374-84 pubmed publisher
Chan T, Pek E, Huth K, Ashkar A. CD4(+) T-cells are important in regulating macrophage polarization in C57BL/6 wild-type mice. Cell Immunol. 2011;266:180-6 pubmed publisher
Ota M, Duong B, Torkamani A, Doyle C, Gavin A, Ota T, et al. Regulation of the B cell receptor repertoire and self-reactivity by BAFF. J Immunol. 2010;185:4128-36 pubmed publisher
Weisel F, Appelt U, Schneider A, Horlitz J, Van Rooijen N, Korner H, et al. Unique requirements for reactivation of virus-specific memory B lymphocytes. J Immunol. 2010;185:4011-21 pubmed publisher
Sweet R, Christensen S, Harris M, Shupe J, Sutherland J, Shlomchik M. A new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formation. Autoimmunity. 2010;43:607-18 pubmed publisher
Duong B, Ota T, Ait Azzouzene D, Aoki Ota M, VELA J, Huber C, et al. Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen. J Immunol. 2010;184:4143-58 pubmed publisher
Giuriato S, Foisseau M, Dejean E, Felsher D, Al Saati T, Demur C, et al. Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia. Blood. 2010;115:4061-70 pubmed publisher
Niess J, Adler G. Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions. J Immunol. 2010;184:2026-37 pubmed publisher
Roundy K, Jacobson A, Weis J, Weis J. The in vitro derivation of phenotypically mature and diverse B cells from immature spleen and bone marrow precursors. Eur J Immunol. 2010;40:1139-49 pubmed publisher
Sadri N, Lu J, Badura M, Schneider R. AUF1 is involved in splenic follicular B cell maintenance. BMC Immunol. 2010;11:1 pubmed publisher
Vale A, Hayashi E, Granato A, Schroeder H, Bellio M, Nobrega A. Genetic control of the B cell response to LPS: opposing effects in peritoneal versus splenic B cell populations. Immunogenetics. 2010;62:41-8 pubmed publisher
Bryan M, Norris K. Genetic immunization converts the trypanosoma cruzi B-Cell mitogen proline racemase to an effective immunogen. Infect Immun. 2010;78:810-22 pubmed publisher
Srinivasan L, Sasaki Y, Calado D, Zhang B, Paik J, Depinho R, et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell. 2009;139:573-86 pubmed publisher
Wols H, Johnson K, Ippolito J, Birjandi S, Su Y, Le P, et al. Migration of immature and mature B cells in the aged microenvironment. Immunology. 2010;129:278-90 pubmed publisher
Roundy K, Weis J, Weis J. Deletion of putative intronic control sequences does not alter cell or stage specific expression of Cr2. Mol Immunol. 2009;47:517-25 pubmed publisher
Lee J, Rauter I, Garibyan L, Ozcan E, Sannikova T, Dillon S, et al. The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function. Blood. 2009;114:2254-62 pubmed publisher
Meyer Bahlburg A, Bandaranayake A, Andrews S, Rawlings D. Reduced c-myc expression levels limit follicular mature B cell cycling in response to TLR signals. J Immunol. 2009;182:4065-75 pubmed publisher
Claudio E, Saret S, Wang H, Siebenlist U. Cell-autonomous role for NF-kappa B in immature bone marrow B cells. J Immunol. 2009;182:3406-13 pubmed publisher
Chevrier S, Genton C, Kallies A, Karnowski A, Otten L, Malissen B, et al. CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche. Proc Natl Acad Sci U S A. 2009;106:3895-900 pubmed publisher
Schuman J, Chen Y, Podd A, Yu M, Liu H, Wen R, et al. A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation. Blood. 2009;113:4566-74 pubmed publisher
Parameswaran R, Ben David H, Sharabi A, Zinger H, Mozes E. B-cell activating factor (BAFF) plays a role in the mechanism of action of a tolerogenic peptide that ameliorates lupus. Clin Immunol. 2009;131:223-32 pubmed publisher
Sekine C, Moriyama Y, Koyanagi A, Koyama N, Ogata H, Okumura K, et al. Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands. Int Immunol. 2009;21:295-301 pubmed publisher
Liu X, Shen S, Manser T. Influence of B cell antigen receptor expression level on pathways of B cell tolerance induction. J Immunol. 2009;182:398-407 pubmed
Babbe H, McMenamin J, Hobeika E, Wang J, Rodig S, Reth M, et al. Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage. J Immunol. 2009;182:347-60 pubmed
Dengler H, Baracho G, Omori S, Bruckner S, Arden K, Castrillon D, et al. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol. 2008;9:1388-98 pubmed publisher
Debnath I, Roundy K, Dunn D, Weiss R, Weis J, Weis J. Defining a transcriptional fingerprint of murine splenic B-cell development. Genes Immun. 2008;9:706-20 pubmed publisher
Racine R, Chatterjee M, Winslow G. CD11c expression identifies a population of extrafollicular antigen-specific splenic plasmablasts responsible for CD4 T-independent antibody responses during intracellular bacterial infection. J Immunol. 2008;181:1375-85 pubmed
Moriyama Y, Sekine C, Koyanagi A, Koyama N, Ogata H, Chiba S, et al. Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice. Int Immunol. 2008;20:763-73 pubmed publisher
Benson M, Dillon S, Castigli E, Geha R, Xu S, Lam K, et al. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J Immunol. 2008;180:3655-9 pubmed
Milne C, Corfe S, Paige C. Heparan sulfate and heparin enhance ERK phosphorylation and mediate preBCR-dependent events during B lymphopoiesis. J Immunol. 2008;180:2839-47 pubmed
Coffey F, Liu X, Manser T. Primary development and participation in a foreign antigen-driven immune response of a chromatin-reactive B cell clonotype are not influenced by TLR9 or other MyD88-dependent TLRs. J Immunol. 2007;179:6663-72 pubmed
Chu V, Enghard P, Riemekasten G, Berek C. In vitro and in vivo activation induces BAFF and APRIL expression in B cells. J Immunol. 2007;179:5947-57 pubmed
Hart G, Avin Wittenberg T, Shachar I. IL-15 regulates immature B-cell homing in an Ly49D-, IL-12 , and IL-18 dependent manner. Blood. 2008;111:50-9 pubmed
Ahuja A, Shupe J, Dunn R, Kashgarian M, Kehry M, Shlomchik M. Depletion of B cells in murine lupus: efficacy and resistance. J Immunol. 2007;179:3351-61 pubmed
Velez M, Kane M, Liu S, Gauld S, Cambier J, Torres R, et al. Ig allotypic inclusion does not prevent B cell development or response. J Immunol. 2007;179:1049-57 pubmed
Liu X, Wysocki L, Manser T. Autoantigen-B cell antigen receptor interactions that regulate expression of B cell antigen receptor Loci. J Immunol. 2007;178:5035-47 pubmed
Sireci G, Russo D, Dieli F, Porcelli S, Taniguchi M, La Manna M, et al. Immunoregulatory role of Jalpha281 T cells in aged mice developing lupus-like nephritis. Eur J Immunol. 2007;37:425-33 pubmed
Fallas J, Yi W, Draghi N, O Rourke H, Denzin L. Expression patterns of H2-O in mouse B cells and dendritic cells correlate with cell function. J Immunol. 2007;178:1488-97 pubmed
Thomas M, Calamito M, Srivastava B, Maillard I, Pear W, Allman D. Notch activity synergizes with B-cell-receptor and CD40 signaling to enhance B-cell activation. Blood. 2007;109:3342-50 pubmed
Gunn K, Brewer J. Evidence that marginal zone B cells possess an enhanced secretory apparatus and exhibit superior secretory activity. J Immunol. 2006;177:3791-8 pubmed
Brummel R, Roberts T, Stacey K, Lenert P. Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice. Eur J Immunol. 2006;36:1951-62 pubmed
Wang C, McDonald K, McDonough J, Newberry R. Murine isolated lymphoid follicles contain follicular B lymphocytes with a mucosal phenotype. Am J Physiol Gastrointest Liver Physiol. 2006;291:G595-604 pubmed
Grimaldi C, Jeganathan V, Diamond B. Hormonal regulation of B cell development: 17 beta-estradiol impairs negative selection of high-affinity DNA-reactive B cells at more than one developmental checkpoint. J Immunol. 2006;176:2703-10 pubmed
Liu X, Manser T. Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro. J Immunol. 2005;174:4505-15 pubmed
Brummel R, Lenert P. Activation of marginal zone B cells from lupus mice with type A(D) CpG-oligodeoxynucleotides. J Immunol. 2005;174:2429-34 pubmed
Waldschmidt T, Conrad D, Lynch R. The expression of B cell surface receptors. I. The ontogeny and distribution of the murine B cell IgE Fc receptor. J Immunol. 1988;140:2148-54 pubmed
Lee W, Rao M, Conrad D. The murine lymphocyte receptor for IgE. IV. The mechanism of ligand-specific receptor upregulation on B cells. J Immunol. 1987;139:1191-8 pubmed
Rao M, Lee W, Conrad D. Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE. J Immunol. 1987;138:1845-51 pubmed
Waldschmidt T, Kroese F, Tygrett L, Conrad D, Lynch R. The expression of B cell surface receptors. III. The murine low-affinity IgE Fc receptor is not expressed on Ly 1 or 'Ly 1-like' B cells. Int Immunol. 1991;3:305-15 pubmed
Rabin E, Cong Y, Wortis H. Loss of CD23 is a consequence of B-cell activation. Implications for the analysis of B-cell lineages. Ann N Y Acad Sci. 1992;651:130-42 pubmed
product information
Product Type :
Antibody
Product Name :
CD23 Monoclonal Antibody (B3B4), eBioscience™
Catalog # :
14-0232-81
Quantity :
50µg
Price :
US 63.5
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 µg/test, Immunohistochemistry: Assay-Dependent
Species :
Mouse
Clone :
B3B4
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test, Immunohistochemistry: Assay-Dependent
Aliases :
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; FCE2; Fc-epsilon-RII; Fcer2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; Low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; Lymphocyte IgE receptor
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA