CD19 Monoclonal Antibody (6OMP31), eBioscience | Invitrogen 14-0194-37 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD19 Monoclonal Antibody (6OMP31), eBioscience

catalog :

14-0194-37

quantity :

2 mg

price :

US 1378.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

6OMP31

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:500; loading ...; fig 2d	Seitz V, Kleo K, Dröge A, Schaper S, Elezkurtaj S, Bedjaoui N, et al. Evidence for a role of RUNX1 as recombinase cofactor for TCRβ rearrangements and pathological deletions in ETV6-RUNX1 ALL. Sci Rep. 2020;10:10024 pubmed publisher
	Celesti F, Gatta A, Shallak M, Chiaravalli A, Cerati M, Sessa F, et al. Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA. Front Immunol. 2023;14:1133177 pubmed publisher
	Zhang Z, Zhai C, Yang X, Li H, Wu L, Li L. Knockdown of CD146 promotes endothelial-to-mesenchymal transition via Wnt/β-catenin pathway. PLoS ONE. 2022;17:e0273542 pubmed publisher
	Ma Y, Yang X, Villalba N, Chatterjee V, Reynolds A, Spence S, et al. Circulating lymphocyte trafficking to the bone marrow contributes to lymphopenia in myocardial infarction. Am J Physiol Heart Circ Physiol. 2022;322:H622-H635 pubmed publisher
	Kim E, Yoon B, Lee S, Choi M, Kim E, Lee B, et al. Fecal microbiota transplantation ameliorates atherosclerosis in mice with C1q/TNF-related protein 9 genetic deficiency. Exp Mol Med. 2022;54:103-114 pubmed publisher
	Liu W, Danckwardt Lilliestr xf6 m N, Schrott Fischer A, Glueckert R, Rask Andersen H. Distribution of Immune Cells Including Macrophages in the Human Cochlea. Front Neurol. 2021;12:781702 pubmed publisher
	Sinha V, Rinkenbaugh A, Xu M, Zhou X, Zhang X, Jeter Jones S, et al. Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast. Nat Commun. 2021;12:5024 pubmed publisher
	Asano Y, Daccache J, Jain D, Ko K, Kinloch A, Veselits M, et al. Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection. Nat Commun. 2021;12:4372 pubmed publisher
	Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, et al. Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice. World J Gastroenterol. 2020;26:918-932 pubmed publisher
	Takemiya T, Takeuchi C, Kawakami M. Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4? T Cells through IL-1? Autocrine Function in Experimental Autoimmune Encephalomyelitis. Int J Mol Sci. 2017;18: pubmed publisher
	Krishnan B, Massilamany C, Basavalingappa R, Gangaplara A, Rajasekaran R, Afzal M, et al. Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice. J Immunol. 2018;200:523-537 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD19 Monoclonal Antibody (6OMP31), eBioscience

Catalog # :

14-0194-37

Quantity :

2 mg

Price :

US 1378.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Frozen): 0.5 µg/mL, Immunohistochemistry (Paraffin): 0.5-5 µg/mL, Western Blot: 1 µg/mL

Species :

Human, Mouse, Rat

Clone :

6OMP31

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.

Immunogen :

E. coli fragment (aa 314-556) of the cytoplasmic domain

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Frozen): 0.5 µg/mL, Immunohistochemistry (Paraffin): 0.5-5 µg/mL, Western Blot: 1 µg/mL

Aliases :

AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

more info or order :

Invitrogen product webpage