product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD16/CD32 Monoclonal Antibody (93), eBioscience
catalog :
14-0161-85
quantity :
500 µg
price :
US 250
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
93
reactivity :
human, mouse
application :
immunocytochemistry, neutralization, flow cytometry, blocking or activating experiments
more info or order :
citations: 532
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; 1:100; loading ...
Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed publisher
  • flow cytometry; mouse; 5 ug/ml
Borggrewe M, Kooistra S, Wesseling E, Gierschek F, Brummer M, Nowak E, et al. VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology. Acta Neuropathol Commun. 2021;9:91 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3a
Garcia Agudo L, Janova H, Sendler L, Arinrad S, Steixner A, Hassouna I, et al. Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. FASEB J. 2019;33:8634-8647 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1e
Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher
  • blocking or activating experiments; mouse; 1:30
Endo Umeda K, Nakashima H, Umeda N, Seki S, Makishima M. Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice. Endocrinology. 2018;159:1419-1432 pubmed publisher
  • blocking or activating experiments; mouse; 1:1000; fig 1a
Liu Z, Ravindranathan R, Kalinski P, Guo Z, Bartlett D. Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy. Nat Commun. 2017;8:14754 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7G
Weindel C, Richey L, Mehta A, Shah M, Huber B. Autophagy in Dendritic Cells and B Cells Is Critical for the Inflammatory State of TLR7-Mediated Autoimmunity. J Immunol. 2017;198:1081-1092 pubmed publisher
  • flow cytometry; mouse; loading ...
Le Q, Yao W, Chen Y, Yan B, Liu C, Yuan M, et al. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 2016;7:e2478 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig s3c
Cordova Z, Grönholm A, Kytölä V, Taverniti V, Hämäläinen S, Aittomäki S, et al. Myeloid cell expressed proprotein convertase FURIN attenuates inflammation. Oncotarget. 2016;7:54392-54404 pubmed publisher
  • flow cytometry; mouse; 1:250; fig st1
Brinkman C, Iwami D, Hritzo M, Xiong Y, Ahmad S, Simon T, et al. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nat Commun. 2016;7:12021 pubmed publisher
  • blocking or activating experiments; mouse; 1:100
Shiraishi M, Shintani Y, Shintani Y, Ishida H, Saba R, Yamaguchi A, et al. Alternatively activated macrophages determine repair of the infarcted adult murine heart. J Clin Invest. 2016;126:2151-66 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2h
  • immunocytochemistry; mouse; loading ...; fig 2c
Schlam D, Canton J, Carreño M, Kopinski H, Freeman S, Grinstein S, et al. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. MBio. 2016;7:e02242 pubmed publisher
  • blocking or activating experiments; mouse
  • flow cytometry; mouse
Foy S, Sennino B, dela Cruz T, Cote J, Gordon E, Kemp F, et al. Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice. PLoS ONE. 2016;11:e0150084 pubmed publisher
  • flow cytometry; mouse
Chen J, Miyanishi M, Wang S, Yamazaki S, Sinha R, Kao K, et al. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature. 2016;530:223-7 pubmed publisher
  • flow cytometry; mouse; 1:400; fig s4
Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
  • flow cytometry; mouse; fig 5, 6
Sagoo P, Garcia Z, Breart B, Lemaître F, Michonneau D, Albert M, et al. In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity. Nat Med. 2016;22:64-71 pubmed publisher
  • blocking or activating experiments; mouse; loading ...
Cole C, Verdoni A, Ketkar S, Leight E, Russler Germain D, Lamprecht T, et al. PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. J Clin Invest. 2016;126:85-98 pubmed publisher
  • flow cytometry; human; tbl 5
Hayashi Y, Bardsley M, Toyomasu Y, Milosavljevic S, Gajdos G, Choi K, et al. Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. Gastroenterology. 2015;149:420-32.e16 pubmed publisher
  • flow cytometry; mouse; fig 1
Johnson A, Costanzo A, Gareau M, Armando A, Quehenberger O, Jameson J, et al. High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PLoS ONE. 2015;10:e0122195 pubmed publisher
  • flow cytometry; mouse; fig 4
Jobsri J, Allen A, Rajagopal D, Shipton M, Kanyuka K, Lomonossoff G, et al. Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody. PLoS ONE. 2015;10:e0118096 pubmed publisher
  • blocking or activating experiments; mouse; 5 ug/ml
Sell S, Dietz M, Schneider A, Holtappels R, Mach M, Winkler T. Control of murine cytomegalovirus infection by γδ T cells. PLoS Pathog. 2015;11:e1004481 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 2c
Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
  • flow cytometry; human
Hannani D, Vétizou M, Enot D, Rusakiewicz S, Chaput N, Klatzmann D, et al. Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25. Cell Res. 2015;25:208-24 pubmed publisher
  • blocking or activating experiments; mouse
Teixeira L, Moreira J, Melo J, Bezerra F, Marques R, Ferreirinha P, et al. Immune response in the adipose tissue of lean mice infected with the protozoan parasite Neospora caninum. Immunology. 2015;145:242-57 pubmed publisher
  • flow cytometry; mouse; fig 2
Krysiak K, Tibbitts J, Shao J, Liu T, Ndonwi M, Walter M. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Exp Hematol. 2015;43:319-30.e10 pubmed publisher
  • flow cytometry; mouse; 1:200
Peschke K, Dudeck A, Rabenhorst A, Hartmann K, Roers A. Cre/loxP-based mouse models of mast cell deficiency and mast cell-specific gene inactivation. Methods Mol Biol. 2015;1220:403-21 pubmed publisher
  • blocking or activating experiments; mouse
Škrnjug I, Guzmán C, Rueckert C, Ruecker C. Cyclic GMP-AMP displays mucosal adjuvant activity in mice. PLoS ONE. 2014;9:e110150 pubmed publisher
  • flow cytometry; mouse
Skrnjug I, Rueckert C, Libanova R, Lienenklaus S, Weiss S, Guzman C. The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages. PLoS ONE. 2014;9:e95728 pubmed publisher
  • flow cytometry; mouse
Satpathy A, Briseño C, Lee J, Ng D, Manieri N, Kc W, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol. 2013;14:937-48 pubmed publisher
  • flow cytometry; mouse; fig 5a
Wu X, Satpathy A, Kc W, Liu P, Murphy T, Murphy K. Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo. PLoS ONE. 2013;8:e64800 pubmed publisher
  • flow cytometry; mouse; fig 7
Vink P, Smout W, Driessen Engels L, de Bruin A, Delsing D, Krajnc Franken M, et al. In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation. PLoS ONE. 2013;8:e57348 pubmed publisher
  • flow cytometry; mouse
Ripich T, Jessberger R. SWAP-70 regulates erythropoiesis by controlling ?4 integrin. Haematologica. 2011;96:1743-52 pubmed publisher
  • immunocytochemistry; mouse; 5 ug/ml; fig 5
Weisel F, Appelt U, Schneider A, Horlitz J, Van Rooijen N, Korner H, et al. Unique requirements for reactivation of virus-specific memory B lymphocytes. J Immunol. 2010;185:4011-21 pubmed publisher
  • flow cytometry; mouse; tbl 1
Zavitz C, Bauer C, Gaschler G, Fraser K, Strieter R, Hogaboam C, et al. Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza. J Immunol. 2010;184:2001-13 pubmed publisher
  • flow cytometry; mouse
Maillard I, Chen Y, Friedman A, Yang Y, Tubbs A, Shestova O, et al. Menin regulates the function of hematopoietic stem cells and lymphoid progenitors. Blood. 2009;113:1661-9 pubmed publisher
  • blocking or activating experiments; mouse
  • flow cytometry; mouse; fig s5
Waskow C, Liu K, Darrasse Jèze G, Guermonprez P, Ginhoux F, Merad M, et al. The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nat Immunol. 2008;9:676-83 pubmed publisher
  • blocking or activating experiments; mouse
Jiang L, Yang P, He H, Li B, Lin X, Hou S, et al. Increased expression of Foxp3 in splenic CD8+ T cells from mice with anterior chamber-associated immune deviation. Mol Vis. 2007;13:968-74 pubmed
  • flow cytometry; mouse; fig 4
Gupta R, Karpatkin S, Basch R. Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase. Blood. 2006;107:1837-46 pubmed
Teng Y, Porfírio Sousa A, Ribeiro G, Arend M, da Silva Meirelles L, Chen E, et al. Analyses of the pericyte transcriptome in ischemic skeletal muscles. Stem Cell Res Ther. 2021;12:183 pubmed publisher
Guo Q, Zhao Y, Li J, Liu J, Yang X, Guo X, et al. Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19. Cell Host Microbe. 2021;29:222-235.e4 pubmed publisher
Shin J, Hong S, Kim M, Lee H, Choi H, Kim J, et al. Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain. Hum Gene Ther. 2021;32:517-527 pubmed publisher
Montecino Rodriguez E, Dorshkind K. Use of Busulfan to Condition Mice for Bone Marrow Transplantation. STAR Protoc. 2020;1:100159 pubmed publisher
Cho S, Rudloff I, Lao J, Pang M, Goldberg R, Bui C, et al. Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities. Nat Commun. 2020;11:5794 pubmed publisher
Mabe N, Garcia N, Wolery S, Newcomb R, Meingasner R, Vilona B, et al. G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program. Cell Rep. 2020;33:108341 pubmed publisher
Schilke R, Blackburn C, Rao S, Krzywanski D, Finck B, Woolard M. Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli. Immunohorizons. 2020;4:659-669 pubmed publisher
Fan C, Feng J, Tang C, Zhang Z, Feng Y, Duan W, et al. Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage. Stem Cell Res Ther. 2020;11:442 pubmed publisher
Ray H, Corliss B, Bruce A, Kesting S, Dey P, Mansour J, et al. Myh11+ microvascular mural cells and derived mesenchymal stem cells promote retinal fibrosis. Sci Rep. 2020;10:15808 pubmed publisher
Konishi H, Okamoto T, Hara Y, Komine O, Tamada H, Maeda M, et al. Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction. EMBO J. 2020;39:e104464 pubmed publisher
Jackson Thompson B, Torrero M, Mitre B, Long J, Packiam M, Mitre E. Axenic Caenorhabditis elegans antigen protects against development of type-1 diabetes in NOD mice. J Transl Autoimmun. 2020;3:100065 pubmed publisher
Hassan A, Kafai N, Dmitriev I, Fox J, Smith B, Harvey I, et al. A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2. Cell. 2020;183:169-184.e13 pubmed publisher
Chamberlin T, Clack M, Silvers C, Kuziel G, Thompson V, Johnson H, et al. Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation. Cancer Res. 2020;80:4465-4475 pubmed publisher
Iske J, Seyda M, Heinbokel T, Maenosono R, Minami K, Nian Y, et al. Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation. Nat Commun. 2020;11:4289 pubmed publisher
Mao M, Xu Y, Zhang X, Yang L, An X, Qu Y, et al. MicroRNA-195 prevents hippocampal microglial/macrophage polarization towards the M1 phenotype induced by chronic brain hypoperfusion through regulating CX3CL1/CX3CR1 signaling. J Neuroinflammation. 2020;17:244 pubmed publisher
Kaya B, Doñas C, Wuggenig P, Diaz O, Morales R, Melhem H, et al. Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis. Cell Rep. 2020;32:107979 pubmed publisher
Markworth J, Brown L, Lim E, Floyd C, Larouche J, Castor Macias J, et al. Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells. JCI Insight. 2020;5: pubmed publisher
Li W, Chen S, Luo Y, Xia Y, Ma Q, Yao Q, et al. Interaction between ICAM1 in endothelial cells and LFA1 in T cells during the pathogenesis of experimental Parkinson's disease. Exp Ther Med. 2020;20:1021-1029 pubmed publisher
Kuziel G, Thompson V, D Amato J, Arendt L. Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells. Cancers (Basel). 2020;12: pubmed publisher
Spenlé C, Loustau T, Murdamoothoo D, Erne W, Beghelli de la Forest Divonne S, Veber R, et al. Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma. Cancer Immunol Res. 2020;8:1122-1138 pubmed publisher
Lau A, Li Z, Danai L, Westermark A, Darnell A, Ferreira R, et al. Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma. elife. 2020;9: pubmed publisher
Wang Z, Ji N, Chen Z, Sun Z, Wu C, Yu W, et al. MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation. Allergy Asthma Immunol Res. 2020;12:859-876 pubmed publisher
Ben Baruch B, Mantsur E, Franco Barraza J, Blacher E, Cukierman E, Stein R. CD38 in cancer-associated fibroblasts promotes pro-tumoral activity. Lab Invest. 2020;100:1517-1531 pubmed publisher
Rogers L, Wang Z, Mott S, Dupuy A, Weiner G. A Genetic Screen to Identify Gain- and Loss-of-Function Modifications that Enhance T-cell Infiltration into Tumors. Cancer Immunol Res. 2020;8:1206-1214 pubmed publisher
Wang Y, Chaffee T, LaRue R, Huggins D, Witschen P, Ibrahim A, et al. Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice. elife. 2020;9: pubmed publisher
Chandran S, Schilke R, Blackburn C, Yurochko A, Mirza R, Scott R, et al. Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization. Front Immunol. 2020;11:787 pubmed publisher
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Liu W, Dai E, Liu Z, Ma C, Guo Z, Bartlett D. In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2. Mol Ther Oncolytics. 2020;17:350-360 pubmed publisher
Kopf A, Renkawitz J, Hauschild R, Girkontaite I, Tedford K, Merrin J, et al. Microtubules control cellular shape and coherence in amoeboid migrating cells. J Cell Biol. 2020;219: pubmed publisher
Yacov N, Kafri P, Salem Y, Propheta Meiran O, Feldman B, Breitbart E, et al. MOSPD2 is a therapeutic target for the treatment of CNS inflammation. Clin Exp Immunol. 2020;201:105-120 pubmed publisher
Lakins M, Koers A, Giambalvo R, Munoz Olaya J, Hughes R, Goodman E, et al. FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models. Clin Cancer Res. 2020;26:4154-4167 pubmed publisher
Zhou J, Li Z, Wu T, Zhao Q, Zhao Q, Cao Y. LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3. J Neuroinflammation. 2020;17:134 pubmed publisher
Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed publisher
Shimokawa C, Kato T, Takeuchi T, Ohshima N, Furuki T, Ohtsu Y, et al. CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes. Nat Commun. 2020;11:1922 pubmed publisher
Han S, Chung D, St Paul M, Liu Z, Garcia Batres C, Elford A, et al. Overproduction of IL-2 by Cbl-b deficient CD4+ T cells provides resistance against regulatory T cells. Oncoimmunology. 2020;9:1737368 pubmed publisher
Huetter J, Gritzan U, Gutcher I, Doecke W, Luetke Eversloh M, Golfier S, et al. Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2). Cancer Immunol Res. 2020;8:895-911 pubmed publisher
Johnson A, Bullock B, Neuwelt A, Poczobutt J, Kaspar R, Li H, et al. Cancer Cell-Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma. J Immunol. 2020;204:2295-2307 pubmed publisher
Li Y, Deng S, Wang X, Huang W, Chen J, Robbins N, et al. Sectm1a Deficiency Aggravates Inflammation-Triggered Cardiac Dysfunction through Disruption of LXRα Signaling in Macrophages. Cardiovasc Res. 2020;: pubmed publisher
Kim E, Ner Gaon H, Varon J, Cullen A, Guo J, Choi J, et al. Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells. J Clin Invest. 2020;130:3238-3252 pubmed publisher
Lin C, Ren W, Luo Y, Li S, Chang Y, Li L, et al. Intratumoral Delivery of a PD-1-Blocking scFv Encoded in Oncolytic HSV-1 Promotes Antitumor Immunity and Synergizes with TIGIT Blockade. Cancer Immunol Res. 2020;8:632-647 pubmed publisher
Brykczynska U, Geigges M, Wiedemann S, Dror E, Böni Schnetzler M, Hess C, et al. Distinct Transcriptional Responses across Tissue-Resident Macrophages to Short-Term and Long-Term Metabolic Challenge. Cell Rep. 2020;30:1627-1643.e7 pubmed publisher
Piao W, Xiong Y, Li L, Saxena V, Smith K, Hippen K, et al. Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration. Cell Rep. 2020;30:1052-1062.e5 pubmed publisher
Yao M, Ventura P, Jiang Y, Rodriguez F, Wang L, Perry J, et al. Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth. Cell. 2020;180:502-520.e19 pubmed publisher
Isobe Y, Sato K, Nishinaga Y, Takahashi K, Taki S, Yasui H, et al. Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer. EBioMedicine. 2020;52:102632 pubmed publisher
Reed Geaghan E, Croxford A, Becher B, Landreth G. Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model. J Exp Med. 2020;217: pubmed publisher
Nguyen T, d Aigle J, Chinea L, Niaz Z, Hunter R, Hwang S, et al. Mycobacterial Trehalose 6,6'-Dimycolate-Induced M1-Type Inflammation. Am J Pathol. 2020;190:286-294 pubmed publisher
Mau T, O Brien M, Ghosh A, Miller R, Yung R. Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging. J Gerontol A Biol Sci Med Sci. 2020;75:89-98 pubmed publisher
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Amer L, Saleh L, WALKER C, Thomas S, Janssen W, Alper S, et al. Inflammation via myeloid differentiation primary response gene 88 signaling mediates the fibrotic response to implantable synthetic poly(ethylene glycol) hydrogels. Acta Biomater. 2019;100:105-117 pubmed publisher
Zeng H, He H, Guo L, Li J, Lee M, Han W, et al. Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies. Cancer Lett. 2019;467:1-8 pubmed publisher
Kim J, Yoon N, Jin S, Diano S. Microglial UCP2 Mediates Inflammation and Obesity Induced by High-Fat Feeding. Cell Metab. 2019;30:952-962.e5 pubmed publisher
Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed publisher
McKenzie M, Ghisi M, Oxley E, Ngo S, Cimmino L, Esnault C, et al. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. Cell Stem Cell. 2019;25:258-272.e9 pubmed publisher
Blomberg R, Beiting D, Wabitsch M, Pure E. Fibroblast activation protein restrains adipogenic differentiation and regulates matrix-mediated mTOR signaling. Matrix Biol. 2019;83:60-76 pubmed publisher
Calvente C, Tameda M, Johnson C, Del Pilar H, Lin Y, Adronikou N, et al. Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223. J Clin Invest. 2019;129:4091-4109 pubmed publisher
Kacherovsky N, Cardle I, Cheng E, Yu J, Baldwin M, Salipante S, et al. Traceless aptamer-mediated isolation of CD8+ T cells for chimeric antigen receptor T-cell therapy. Nat Biomed Eng. 2019;: pubmed publisher
Kolter J, Feuerstein R, Zeis P, Hagemeyer N, Paterson N, d Errico P, et al. A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves. Immunity. 2019;50:1482-1497.e7 pubmed publisher
Kataru R, Ly C, Shin J, Park H, Baik J, Rehal S, et al. Tumor lymphatic function regulates tumor inflammatory and immunosuppressive microenvironments. Cancer Immunol Res. 2019;: pubmed publisher
Gu A, Li D, Wei D, Liu Y, Ji W, Yang Y, et al. Cytochrome P450 26A1 modulates uterine dendritic cells in mice early pregnancy. J Cell Mol Med. 2019;23:5403-5414 pubmed publisher
Li Y, Yang Y, Gan T, Zhou J, Hu F, Hao N, et al. Extracellular RNAs from lung cancer cells activate epithelial cells and induce neutrophil extracellular traps. Int J Oncol. 2019;55:69-80 pubmed publisher
Duan X, Chan C, Han W, Guo N, Weichselbaum R, Lin W. Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors. Nat Commun. 2019;10:1899 pubmed publisher
Meln I, Wolff G, Gajek T, Koddebusch J, Lerch S, Harbrecht L, et al. Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth. Mol Metab. 2019;24:139-148 pubmed publisher
Eisemann T, Costa B, Peterziel H, Angel P. Podoplanin Positive Myeloid Cells Promote Glioma Development by Immune Suppression. Front Oncol. 2019;9:187 pubmed publisher
Reidy P, McKenzie A, Mahmassani Z, Petrocelli J, Nelson D, Lindsay C, et al. Aging impairs mouse skeletal muscle macrophage polarization and muscle-specific abundance during recovery from disuse. Am J Physiol Endocrinol Metab. 2019;317:E85-E98 pubmed publisher
Pionnier N, Sjoberg H, Chunda V, Fombad F, Chounna P, Njouendou A, et al. Mouse models of Loa loa. Nat Commun. 2019;10:1429 pubmed publisher
Palmer B, Jatana S, Phelan Dickinson S, Delouise L. Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis. Sci Rep. 2019;9:5085 pubmed publisher
Li H, Petersen S, García Mariscal A, Brakebusch C. Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. Cancer Res. 2019;79:2167-2181 pubmed publisher
Li H, Fan C, Feng C, Wu Y, Lu H, He P, et al. Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity. Br J Pharmacol. 2019;176:2209-2226 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
CD16/CD32 Monoclonal Antibody (93), eBioscience
Catalog # :
14-0161-85
Quantity :
500 µg
Price :
US 250
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
Species :
Mouse
Clone :
93
Isotype :
IgG2a, lambda
Storage :
4° C
Description :
CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
Aliases :
AI528646; CD16; CD16a; CD16a antigen; CD16B; CD32; CD32 receptor 2; CD32B; CDw32; F630109E10Rik; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIIa; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16a); fc gamma receptor IIB; Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor RII; Fc gamma RIIB; Fc gamma RIIIa; Fc receptor, IgG, low affinity IIb; Fc receptor, IgG, low affinity III; Fc[g]RII; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD16); fc-gamma RII; Fc-gamma RII-b; Fc-gamma RII-c; Fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; Fc-gamma-RII; FcgammaRIIB; fc-gamma-RIIB; Fc-gamma-RIIc; FcgammaRIII; FcgammaRIIIA; Fcgr2; Fcgr2a; Fcgr2b; FCGR2C; Fcgr3; FCGR3A; FCGR3B; FcgRII; FCGRIII; FCR-10; Fcr-2; Fcr-3; fcRII; FcRII-b; FcRII-c; FCRIII; FCRIIIA; FGFR2B; IGFR3; IgG Fc receptor II beta; IgG Fc receptor III; IgG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; low affinity immunoglobulin gamma Fc region receptor III; Low affinity immunoglobulin gamma Fc region receptor III-A; Ly-17; Lym-1; Ly-m20; lymphocyte antigen 17; neutrophil-specific antigen NA; RP11-5K23.1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA