CD15 Monoclonal Antibody (HI98), eBioscience™ | Invitrogen 14-0159-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD15 Monoclonal Antibody (HI98), eBioscience™

catalog :

14-0159-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HI98

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Mandl M, Schmitz S, Weber C, Hristov M. Characterization of the CD14++CD16+ monocyte population in human bone marrow. PLoS ONE. 2014;9:e112140 pubmed publisher
	Gong C, Valduga J, Chateau A, Richard M, Pellegrini Moïse N, Barberi Heyob M, et al. Stimulation of medulloblastoma stem cells differentiation by a peptidomimetic targeting neuropilin-1. Oncotarget. 2018;9:15312-15325 pubmed publisher
	McKenney A, Lau A, Somasundara A, Spitzer B, Intlekofer A, Ahn J, et al. JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. J Clin Invest. 2018;128:789-804 pubmed publisher
	Schwartz J, Ma J, Lamprecht T, Walsh M, Wang S, Bryant V, et al. The genomic landscape of pediatric myelodysplastic syndromes. Nat Commun. 2017;8:1557 pubmed publisher
	Ding L, Hayes M, Photenhauer A, Eaton K, Li Q, Ocadiz Ruiz R, et al. Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia. J Clin Invest. 2016;126:2867-80 pubmed publisher
	Melief J, Schuurman K, van de Garde M, Smolders J, van Eijk M, Hamann J, et al. Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed. Glia. 2013;61:1848-61 pubmed publisher
	Tadzić R, Mihalj M, Vcev A, Ennen J, Tadzic A, Drenjancevic I. The effects of arterial blood pressure reduction on endocan and soluble endothelial cell adhesion molecules (CAMs) and CAMs ligands expression in hypertensive patients on Ca-channel blocker therapy. Kidney Blood Press Res. 2013;37:103-15 pubmed publisher
	Melief J, Koning N, Schuurman K, van de Garde M, Smolders J, Hoek R, et al. Phenotyping primary human microglia: tight regulation of LPS responsiveness. Glia. 2012;60:1506-17 pubmed publisher
	Hamilton E, Pearce L, Morgan L, Robinson S, Ware V, Brennan P, et al. Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells. Br J Haematol. 2012;158:589-99 pubmed publisher
	Koleva R, Ficarro S, Radomska H, Carrasco Alfonso M, Alberta J, Webber J, et al. C/EBP? and DEK coordinately regulate myeloid differentiation. Blood. 2012;119:4878-88 pubmed publisher
	van de Laar L, van den Bosch A, Wierenga A, Janssen H, Coffer P, Woltman A. Tight control of STAT5 activity determines human CD34-derived interstitial dendritic cell and langerhans cell development. J Immunol. 2011;186:7016-24 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD15 Monoclonal Antibody (HI98), eBioscience™

Catalog # :

14-0159-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL

Species :

Human

Clone :

HI98

Isotype :

IgM, kappa

Storage :

4° C

Description :

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL

more info or order :

Invitrogen product webpage