CD10 Monoclonal Antibody (eBioCB-CALLA (CB-CALLA)), eBioscience™ | Invitrogen 14-0106-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD10 Monoclonal Antibody (eBioCB-CALLA (CB-CALLA)), eBioscience™

catalog :

14-0106-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eBioCB-CALLA (CB-CALLA)

reactivity :

human, mouse

application :

immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 7	Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Hayashi T, Nakachi K, et al. Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. J Immunol. 2017;199:2777-2793 pubmed publisher
flow cytometry; human; loading ...; fig st9	Ferre E, Rose S, Rosenzweig S, Burbelo P, Romito K, Niemela J, et al. Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. JCI Insight. 2016;1: pubmed
flow cytometry; mouse; loading ...	Okoye Okafor U, Bartholdy B, Cartier J, Gao E, Pietrak B, Rendina A, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015;11:878-86 pubmed publisher
flow cytometry; human	Grieco A, Billett H, Green N, Driscoll M, Bouhassira E. Variation in Gamma-Globin Expression before and after Induction with Hydroxyurea Associated with BCL11A, KLF1 and TAL1. PLoS ONE. 2015;10:e0129431 pubmed publisher
flow cytometry; human	ZinÃ¶cker S, Schindler C, Skinner J, Rogosch T, Waisberg M, Schickel J, et al. The V gene repertoires of classical and atypical memory B cells in malaria-susceptible West African children. J Immunol. 2015;194:929-39 pubmed publisher
	Hu X, Song C, Fang M, Li C. Simvastatin inhibits the apoptosis of hippocampal cells in a mouse model of Alzheimer's disease. Exp Ther Med. 2018;15:1795-1802 pubmed publisher
	Paik D, Janzen D, Schafenacker A, Velasco V, Shung M, Cheng D, et al. Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation. Stem Cells. 2012;30:2487-97 pubmed publisher
	Biswas S, Chang H, Sarkis P, Fikrig E, Zhu Q, Marasco W. Humoral immune responses in humanized BLT mice immunized with West Nile virus and HIV-1 envelope proteins are largely mediated via human CD5+ B cells. Immunology. 2011;134:419-33 pubmed publisher
	De Gobbi M, Garrick D, Lynch M, Vernimmen D, Hughes J, Goardon N, et al. Generation of bivalent chromatin domains during cell fate decisions. Epigenetics Chromatin. 2011;4:9 pubmed publisher
	Gladkikh A, Potashnikova D, Korneva E, Khudoleeva O, Vorobjev I. Cyclin D1 expression in B-cell lymphomas. Exp Hematol. 2010;38:1047-57 pubmed publisher
	Ritz J, Pesando J, Notis McConarty J, Lazarus H, Schlossman S. A monoclonal antibody to human acute lymphoblastic leukaemia antigen. Nature. 1980;283:583-5 pubmed

product information

Product Type :

Antibody

Product Name :

CD10 Monoclonal Antibody (eBioCB-CALLA (CB-CALLA)), eBioscience™

Catalog # :

14-0106-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 5 µg/mL

Species :

Human

Clone :

eBioCB-CALLA (CB-CALLA)

Isotype :

IgG2b, kappa

Storage :

4° C

Description :

CD10 (Common Acute Lymphocytic Leukemia Antigen, CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. CD10 is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. Further, CD10 is a 100 kDa type II transmembrane glycoprotein that exists in a single copy of greater than 45 kb. The 5' untranslated region of the CD10 gene is alternatively spliced, resulting in four separate mRNA transcripts and the coding region is not affected by alternative splicing. Diseases associated with CD10 dysfunction include spinocerebellar ataxia 43 and Charcot-Marie tooth Disease.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 5 µg/mL

Aliases :

6030454K05Rik; Atriopeptidase; C85356; CALLA; CD10; CMT2T; common acute lymphoblastic leukemia antigen; common acute lymphocytic leukemia antigen; Enkephalinase; EPN; membrane metallo endopeptidase; membrane metalloendopeptidase; membrane metallo-endopeptidase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; MME; NEP; neprilysin; neprilysin-390; neprilysin-411; neutral endopeptidase 24.11; SFE; Skin fibroblast elastase

more info or order :

Invitrogen product webpage