CD9 Monoclonal Antibody (eBioSN4 (SN4 C3-3A2)), eBioscience | Invitrogen 14-0098-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD9 Monoclonal Antibody (eBioSN4 (SN4 C3-3A2)), eBioscience

catalog :

14-0098-37

quantity :

2 mg

price :

US 1492.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eBioSN4 (SN4 C3-3A2)

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

citations: 10

Reference
Lapin M, Tjensvoll K, Nedreb xf8 K, Taksdal E, Janssen H, Gilje B, et al. Extracellular vesicles as a potential source of tumor-derived DNA in advanced pancreatic cancer. PLoS ONE. 2023;18:e0291623 pubmed publisher
Sunartvanichkul T, Arayapisit T, Sangkhamanee S, Chaweewannakorn C, Iwasaki K, Klaihmon P, et al. Stem cell-derived exosomes from human exfoliated deciduous teeth promote angiogenesis in hyperglycemic-induced human umbilical vein endothelial cells. J Appl Oral Sci. 2023;31:e20220427 pubmed publisher
Dash S, Wu C, Wu C, Chiang S, Lu Y, Yeh C, et al. Extracellular Vesicle Membrane Protein Profiling and Targeted Mass Spectrometry Unveil CD59 and Tetraspanin 9 as Novel Plasma Biomarkers for Detection of Colorectal Cancer. Cancers (Basel). 2022;15: pubmed publisher
Santos M, Rappa G, Fontana S, Karbanov xe1 J, Aalam F, Tai D, et al. Anti-Human CD9 Fab Fragment Antibody Blocks the Extracellular Vesicle-Mediated Increase in Malignancy of Colon Cancer Cells. Cells. 2022;11: pubmed publisher
Xing C, Xu W, Shi Y, Zhou B, Wu D, Liang B, et al. CD9 knockdown suppresses cell proliferation, adhesion, migration and invasion, while promoting apoptosis and the efficacy of chemotherapeutic drugs and imatinib in Ph+ ALL SUP‑B15 cells. Mol Med Rep. 2020;22:2791-2800 pubmed publisher
Rodriguez L, Pekkarinen P, Lakshmikanth T, Tan Z, Consiglio C, Pou C, et al. Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19. Cell Rep Med. 2020;1:100078 pubmed publisher
Olin A, Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, et al. Stereotypic Immune System Development in Newborn Children. Cell. 2018;174:1277-1292.e14 pubmed publisher
Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, et al. Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis. Nat Commun. 2018;9:17 pubmed publisher
Dorrell C, Schug J, Canaday P, Russ H, Tarlow B, Grompe M, et al. Human islets contain four distinct subtypes of ? cells. Nat Commun. 2016;7:11756 pubmed publisher
Wu S, Ju G, Du T, Zhu Y, Liu G. Microvesicles derived from human umbilical cord Wharton's jelly mesenchymal stem cells attenuate bladder tumor cell growth in vitro and in vivo. PLoS ONE. 2013;8:e61366 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD9 Monoclonal Antibody (eBioSN4 (SN4 C3-3A2)), eBioscience

Catalog # :

14-0098-37

Quantity :

2 mg

Price :

US 1492.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 ug/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Human

Clone :

eBioSN4 (SN4 C3-3A2)

Isotype :

IgG1, kappa

Storage :

4 C

Description :

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

5H9; 5H9 antigen; antigen CD9; BA2; BA-2/p24 antigen; BTCC-1; CD9; CD9 antigen; CD9 antigen (p24); CD9 molecule; cell growth-inhibiting gene 2 protein; DRAP-27; GIG2; Leukocyte antigen MIC3; MIC3; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin29; Tetraspanin-29; transmembrane protein CD9; TSPAN29; Tspan-29