CD274 (PD-L1, B7-H1) Monoclonal Antibody (1-111A), Biotin, eBioscience | Invitrogen 13-9971-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD274 (PD-L1, B7-H1) Monoclonal Antibody (1-111A), Biotin, eBioscience

catalog :

13-9971-81

quantity :

50 µg

price :

US 156

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

1-111A

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 1f	Tan S, Chowdhury S, Polak N, Gorrell M, Weninger W. Fibroblast activation protein is dispensable in the anti-influenza immune response in mice. PLoS ONE. 2017;12:e0171194 pubmed publisher
	Drees J, Augustin L, Mertensotto M, Schottel J, Leonard A, Saltzman D. Soluble production of a biologically active single-chain antibody against murine PD-L1 in Escherichia coli. Protein Expr Purif. 2014;94:60-6 pubmed publisher
	van der Merwe M, Abdelsamed H, Seth A, Ong T, Vogel P, Pillai A. Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation. J Immunol. 2013;191:5764-76 pubmed publisher
	Huber S, Hoffmann R, Muskens F, Voehringer D. Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2. Blood. 2010;116:3311-20 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD274 (PD-L1, B7-H1) Monoclonal Antibody (1-111A), Biotin, eBioscience

Catalog # :

13-9971-81

Quantity :

50 µg

Price :

US 156

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

1-111A

Isotype :

IgG2a, kappa

Storage :

4° C, do not freeze

Description :

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1

more info or order :

Invitrogen product webpage