This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD338 (ABCG2) Monoclonal Antibody (5D3), Biotin, eBioscience
catalog :
13-8888-82
quantity :
100 ug
price :
US 292.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
5D3

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 8
Reference
Feng D, Yan K, Liang H, Liang J, Wang W, Yu H, et al. CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2. Neoplasia. 2021;23:1-11 pubmed publisher
Feng D, Yan K, Zhou Y, Liang H, Liang J, Zhao W, et al. Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis. Oncotarget. 2016;7:64575-64588 pubmed publisher
Marriott S, Baskir R, Gaskill C, Menon S, Carrier E, Williams J, et al. ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Am J Physiol Cell Physiol. 2014;307:C684-98 pubmed publisher
Foster B, Gangavarapu K, Mathew G, Azabdaftari G, Morrison C, Miller A, et al. Human prostate side population cells demonstrate stem cell properties in recombination with urogenital sinus mesenchyme. PLoS ONE. 2013;8:e55062 pubmed publisher
Padmanabhan R, Chen K, Gillet J, Handley M, Mallon B, Hamilton R, et al. Regulation and expression of the ATP-binding cassette transporter ABCG2 in human embryonic stem cells. Stem Cells. 2012;30:2175-87 pubmed publisher
Basseville A, Tamaki A, Ierano C, Trostel S, Ward Y, Robey R, et al. Histone deacetylase inhibitors influence chemotherapy transport by modulating expression and trafficking of a common polymorphic variant of the ABCG2 efflux transporter. Cancer Res. 2012;72:3642-51 pubmed publisher
Imai Y, Yoshimori M, Fukuda K, Yamagishi H, Ueda Y. The PI3K/Akt inhibitor LY294002 reverses BCRP-mediated drug resistance without affecting BCRP translocation. Oncol Rep. 2012;27:1703-9 pubmed publisher
Ni Z, Bikadi Z, Shuster D, Zhao C, Rosenberg M, Mao Q. Identification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity. Biochemistry. 2011;50:8057-66 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD338 (ABCG2) Monoclonal Antibody (5D3), Biotin, eBioscience
Catalog # :
13-8888-82
Quantity :
100 ug
Price :
US 292.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1 ug/test
Species :
Human
Clone :
5D3
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/test
Aliases :
ABC transporter; ABC15; Abcg2; ABCP; AI428558; ATP binding cassette subfamily G member 2 (Junior blood group); ATP-binding cassette sub-family G member 2; ATP-binding cassette transporter G2; ATP-binding cassette, sub-family G (WHITE), member 2; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group); BCRP; Bcrp1; BMDP; Breast cancer resistance protein; breast cancer resistance protein 1 homolog; Broad substrate specificity ATP-binding cassette transporter ABCG2; CD338; CDw338; EST157481; GOUT1; mitoxantrone resistance protein 1; mitoxantrone resistance-associated protein; MRX; multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2; MXR; MXR1; MXR-1; placenta specific MDR protein; placenta-specific ATP-binding cassette transporter; UAQTL1; Urate exporter
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA