gamma Catenin Monoclonal Antibody (PG-11E4) | Invitrogen 13-8500 product information

product summary

company name :

Invitrogen

other brands :

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product type :

antibody

product name :

gamma Catenin Monoclonal Antibody (PG-11E4)

catalog :

13-8500

quantity :

100 µg

price :

US 449.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PG-11E4

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:500; fig 3a western blot; mouse; 1:1000; fig 3b	Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
western blot; mouse; fig 6	Val S, Burgett K, Brown K, Preciado D. SuperSILAC Quantitative Proteome Profiling of Murine Middle Ear Epithelial Cell Remodeling with NTHi. PLoS ONE. 2016;11:e0148612 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:300	Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, et al. EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol. 2012;371:136-45 pubmed publisher
immunocytochemistry; human western blot; human	Law M, Corsino P, Jahn S, Davis B, Chen S, Patel B, et al. Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms. Oncogene. 2013;32:1316-29 pubmed publisher
immunohistochemistry; human; 1:150; fig 1	Wex T, Kuester D, Monkemuller K, Stahr A, Fry L, Kandulski A, et al. Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection. Hum Pathol. 2012;43:1745-54 pubmed publisher
immunohistochemistry; human; 1:150; fig 1	Wex T, Monkemuller K, Stahr A, Kuester D, Fry L, Völkel S, et al. Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa. Histopathology. 2012;60:405-15 pubmed publisher
immunoprecipitation; human; fig 1	Lai Y, Cheng J, Cheng D, Feasel M, Beste K, Peng J, et al. SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. BMC Cell Biol. 2011;12:50 pubmed publisher
immunocytochemistry; human; fig 4	Akat K, Bleck C, Lee Y, Haselmann Weiss U, Kartenbeck J. Characterization of a novel type of adherens junction in meningiomas and the derived cell line HBL-52. Cell Tissue Res. 2008;331:401-12 pubmed
western blot; human	Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 2008;111:142-9 pubmed
immunoprecipitation; rat; tbl 1 western blot; rat; tbl 1	Sarkar O, Xia W, Mruk D. Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions. J Cell Physiol. 2006;208:175-87 pubmed
immunocytochemistry; mouse; fig 4 western blot; mouse	Kim Y, Sauer C, Testa K, Wahl J, Svoboda R, Johnson K, et al. Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex. J Cell Sci. 2005;118:3883-94 pubmed
western blot; mouse	Grooteclaes M, Deveraux Q, Hildebrand J, Zhang Q, Goodman R, Frisch S. C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. Proc Natl Acad Sci U S A. 2003;100:4568-73 pubmed
western blot; human; fig 3	Luber B, Candidus S, Handschuh G, Mentele E, Hutzler P, Feller S, et al. Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate. Cell Adhes Commun. 2000;7:391-408 pubmed
	Bastida Ruiz D, Yart L, Wuillemin C, Ribaux P, Morris N, Epiney M, et al. The fine-tuning of endoplasmic reticulum stress response and autophagy activation during trophoblast syncytialization. Cell Death Dis. 2019;10:651 pubmed publisher
	Price A, Cost A, Ungewiß H, Waschke J, Dunn A, Grashoff C. Mechanical loading of desmosomes depends on the magnitude and orientation of external stress. Nat Commun. 2018;9:5284 pubmed publisher
	Rajkumar R, Sembrat J, McDonough B, Seidman C, Ahmad F. Functional effects of the TMEM43 Ser358Leu mutation in the pathogenesis of arrhythmogenic right ventricular cardiomyopathy. BMC Med Genet. 2012;13:21 pubmed publisher
	Lombardi R, da Graça Cabreira Hansen M, Bell A, Fromm R, Willerson J, Marian A. Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res. 2011;109:1342-53 pubmed publisher
	Lombardi R, Dong J, Rodriguez G, Bell A, Leung T, Schwartz R, et al. Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res. 2009;104:1076-84 pubmed publisher
	Mruk D, Lau A, Sarkar O, Xia W. Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis. J Androl. 2007;28:742-54 pubmed
	Smith A, Miller L, Song N, Taketo M, Lang R. The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Dev Biol. 2005;285:477-89 pubmed
	Silberberg M, Charron A, Bacallao R, Wandinger Ness A. Mispolarization of desmosomal proteins and altered intercellular adhesion in autosomal dominant polycystic kidney disease. Am J Physiol Renal Physiol. 2005;288:F1153-63 pubmed
	Descargues P, Deraison C, Bonnart C, Kreft M, Kishibe M, Ishida Yamamoto A, et al. Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity. Nat Genet. 2005;37:56-65 pubmed
	Kaplan D, Meigs T, Kelly P, Casey P. Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle. J Biol Chem. 2004;279:10829-32 pubmed
	Chidgey M, Brakebusch C, Gustafsson E, Cruchley A, Hail C, Kirk S, et al. Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation. J Cell Biol. 2001;155:821-32 pubmed
	Sundstrom J, McMullan L, Spiropoulou C, Hooper W, Ansari A, Peters C, et al. Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells. J Virol. 2001;75:6070-85 pubmed

product information

Product Type :

Antibody

Product Name :

gamma Catenin Monoclonal Antibody (PG-11E4)

Catalog # :

13-8500

Quantity :

100 µg

Price :

US 449.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:250

Species :

Human, Mouse

Clone :

PG-11E4

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

Immunogen :

Fusion protein consisting of the maltose binding protein fused to full length human plakoglobin protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:250

Aliases :

ARVD12; catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; cb80; cell-adhesion protein plakoglobin; Ctnng; D930025P04Rik; danPG; Desmoplakin III; desmoplakin-3; desmosomal protein; DP3; DPIII; fb11b06; gama-catenin; gamma-catenin; gamma-catenin (plakoglobin); junction plakoglobin; junction plakoglobin a; Jup; jup protein; jupa; OTTHUMP00000164735; PDGB; PG; PKGB; plakoglobin; wu:fb11b06

more info or order :

Invitrogen product webpage